“highly significant”

The CCDR Score demonstrated moderate negative correlations with VSMT (r = −0.347, p = 0.008) and GFC_VSMT (r = −0.368, p = 0.005), as well as stronger negative correlations with GFC_CCDR (Regression) (r = −0.628), GFC_CCDR (Discriminant) (r = −0.504), and the GFC_Health Problems Score (r = −0.471), all of which were highly significant ( p < 0.0002).

Given the fraction of total axis length that was asynapsed in these syp-1 RNAi mnT12 nuclei, the observed restriction of GFP::COSA-1 foci to synapsed segments (where homologs are closely juxtaposed) represents a highly significant (χ 2 test; p = 0.0002) departure from the distribution expected if GFP::COSA-1 foci were equally likely to occur on synapsed segments and asynapsed segments (where homologs are separated), consistent with the interpretation that these GFP::COSA-1 foci correspond to interhomolog recombination events. 6 Extended Data Figure 4.

Biological process annotations of these genes showed highly significant enrichment for lipid metabolism genes (P = 0.0002).

There were pathogenic deletion variants in 5.26% of females and 3.69% of males, and this difference was highly significant (P < 0.0002) ( Fig. 2B ).

Glucose demonstrated highly significant treatment ( P = 0.0002) and day ( P < 0.0001) effects, with a sharp decline by day 30 in all groups to hypoglycemic levels of 1.30, 2.10, and 1.70 mmol/L in NE0, NE20, and NE40, respectively; initial values were higher in supplemented ewes.

This analysis showed a highly significant difference ( p = 0.0002), highlighting that fistulectomy improves the quality of postoperative evacuations by promoting more formed and regular stools than fistulotomy.

All the correlations were highly significant ( p = 0.0002, p < 0.0001, and p < 0.0001, respectively).

Both the power law and the exponential models fitted well, with high R 2 values (0.999077 and 0.99942, respectively) and being highly significant ( p < .0002).

The enrichment for Cys-proximal N-linked glycosylation at the bases of the hyper-variable loops is highly significant (6/8 vs 0/16, p = 0.0002).

A highly significant correlation existed between K i values and IC 50 values ( r = 0.82, P = 0.0002).

For instance, nine of our candidate cancer genes were also contained in the Cancer Gene Census list, which comprises 487 genes causally linked to cancer [ 11 ], representing a highly significant enrichment ( Abl2 , Braf , Fbxw7 , Foxp1 , Ipo11 , Mllt3 , Fas , Pten , and Nf1 ; p<0.0002, Fisher’s exact test).

The difference in numbers of the competitors between the two time periods at the 1900 m site was highly significant ( Χ 3 2 = 20.1, P = 0.0002).

At 6 months, both groups differed in a highly significant way: While ingrowth index in the CPC group was only 0.33%, it was 3.79% in the SPC group ( p = 0.0002) (Figure 6 ), indicating that after 6 months, a higher percentage of more than ten times in intra-implant bone formation occurred within the SPC implants.

In sensitivity analysis, after excluding one study, the analysis revealed a highly significant effect in favor of PRP with a homogenous effect (MD = 0.83, 95% CI: 0.39, 1.26, P = 0.0002, I2 = 0%) (Figure 10 ).

For females, this resulted in highly significant subspecies divergence in contact (t 55 = −4.19, P = 0.0002) but not allopatric samples (t 18 = −0.14, P = 0.89).

In the female subsample, the effects of DDSS and age were both highly significant (Q = 14.7; p = 0.0002, Q = 23.8; p < 0.0001, respectively), but the effect of DDSS on usability ratings was different for younger patients than it was for older participants (Q = 7.9; p = 0.005), suggesting that younger women (<52 years) showed greater usability rating differences between Ada and Rheport.

In contrast, the reduction in leukocyte counts was highly significant (P = 0.0002, F = 6.11) at the 0.05 level.

To reduce the bias of time to HSCT2 we analyzed only patients having HSCT2 within 6 months of relapse and found that having HSCT2 was a highly significant predictive factor in this univariate analysis ( P =0.0002).

However, subtle recovery differences in RPS between treatments were observed at distinct recovery times after the first values taken 12 hours after the eccentric exercise: the RPS differences between 12 and 36 hours post eccentric exercise were highly significant ( p = 0.0002) with blueberries, whereas only a slight difference was observed between these two time points in the control condition ( p = 0.031).

However, we did find a highly significant increase in the rare/common CNV ratio in the LFS patients carrying mutations in the TP53 DBD when compared to both controls (p=0.0002) and to patients carrying the p.R337H mutation (p=0.0156; Fisher-exact test) (Figure 1B ).

Moreover, multiple comparison analysis showed highly significant levels of β-III tubulin ( P = 0.0002), Nf-L ( P = 0.0403) and GFAP ( P < 0.015) in the subgroup of CSZ clozapine-treated.

However BSO has a highly significant (p = 0.0002) effect in these cells when used in combination with 8 μM ATO.

Highly significant association was seen between breast cancer and carrying either of the mutations (OR 1.86, 95% CI 1.32–2.49, P = 0.0002).

Highly significant differences in overjet: - Both condyles Δ x ≥ 2 mm → p = 0.0002; - Δz ≥ 2 mm → p = 0.001 (left), p = 0.007 (right).

An unexpected finding is that gender also had a highly significant effect ( F = 14.66, p = 0.0002).