“highly significant”

For risk groups, a highly significant (likelihood ratio test p = 0.0002) Cox proportional-hazards model included statistically significant covariates age (HR 1.1 (1.0 − 1.2) p = 0.004), stage IV (HR 173.8 (9.1 − 3325.5) p = 0.0006), and invasive ductal (ICD-0-3 code 8500/3) histologic type (HR 0.06 (0.006 − 0.68) p = 0.023).

Regression analysis confirmed a highly significant correlation between expression of CXCL11 and TBET (p=0.0002), or Granzyme B (p=0.0055), respectively (Figure 4C ), but not between CXCL11 and GATA3, RORC or FOXP3 (not shown).

Upon quantification (Figure 6B ), this increase in mortality was highly significant ( p = 0.0002 as compared with TFN; p = 0.0089 as compared with PF477736 and p = 0.0245 as compared with camptothecin).

Substantial and highly significant levels of correlation between initial attainment rate and neutral zone were found for left (Rho = 0.75, P = 0.0002) and combined left-right bending (Rho = 0.72, P = 0.0001) and moderate ones for right alone (Rho = 0.55, P = 0.0012).

It was found that 90% of patients had a highly significant decrease in MO on immediate postoperative period ( P = 0.0002).

This difference was highly significant (GROUP effect: F = 21.18; P = 0.0002; Fig. 3a ) and was apparent during both the ramp and hold phases, and at both force levels (P = 0.01).

The gender difference is highly significant (t(62) = 3.83, p < 0.0002, two-tailed, with an effect size Cohen’s d = 1.025).

As expected, a highly significant correlation was observed between the number of Gag escape mutants associated with the protective HLA alleles and decreasing VRC (r = -0.33, p = 0.0002, Fig 4A ).

Furthermore, the interaction between baseline FS and treatment arm is highly significant ( P =0.0002; Table 2 ).

Moreover, a statistically significant ( P < 0.004) interaction between the organ sampling-time and the SNP treatment was revealed in kidney regardless of the dosing time, whereas a highly significant ( P < 0.0002) interaction was validated in liver only in animals injected at 13 HALO. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

miR-125a-5p showed a highly significant association, with a genetically predicted increase in expression associated with a 26% reduction in AD risk (OR = 0.74, 95% CI: 0.64–0.87, P=2.05e−4).

We found that FoxC1-induced genes were enriched among native SGCs relative to ECs, and that this enrichment was highly significant ( P = 2.1 × 10 –4 ).

Instead, there was a highly significant relationship between serum IFN-α and LRRC20 genotype in a joint analysis of European- and Hispanic-American subjects ( P = 2.1 × 10 -4 ), in whom the serologic association with anti-La antibodies was not present (Supplemental figure S2 in Additional file 1 ).

Overall, the Leu372Val substitution had a highly significant effect on surface expression (ANOVA, p = 0.00021), while there was no effect ascribable to the Thr357Ala replacement (p = 0.579).

As discussed in Results , the identification of 10 of 54 genes with a link to HIV-1 replication is a highly significant over-representation (p value<0.00021) over the expected number (2.4) in randomly generated lists of 54 genes that are expressed in both Jurkat and MM6 cells.

For Model 1, the fit was highly significant (t(54) = 3.98, p = .00021), whereas the fit for Model 2 only bordered significance (t(54) = 1.88, p = .066).

The findings demonstrate significant variances between stage I and II ( P = 0.027), highly significant variances between stage I and III ( P = 0.00021), and extremely significant variances between stage I and IV ( P = 0.0054).

Since duration apparently influenced the success of mountings, we tested for an effect of location and found a highly significant male species × female species × location interaction (χ 2 = 18.89, df = 1, P = 0.00022), driven mainly by short interspecific matings in the sympatric, but not in the allopatric combinations (Fig. 1 A).

The difference between the two groups was highly significant ( p = 0.00022), with a mean difference (−1.801 kcal/mol) substantially exceeding the inherent noise level of the scoring protocol.

For example, the protective effect of CCBs on dental caries risk in the FinnGen cohort remained highly significant in the MR‐PRESSO analysis (OR: 0.9709; 95% CI: 0.9503–0.9837; p = 2.23 × 10 −4 ) reinforcing the validity of our primary findings. 3.3.

Moreover, highly significant differences were identified for the eraser FTO ( P =2.257x10 -4 ), the strongest obesity candidate gene identified in genetic studies ( 19 ).

The fit of the log–logistic model ( eq 2 ) was highly significant ( p -value = 2.27 × 10 –4 ) and resulted in a EC 50 value of 3.57% sediment dw (±3.22) and an EC 10 value of 1.07% ( SI Figure S3 ).

6 expected), supported by a highly significant PPI enrichment value ( p = 0.000228).

the threshold of 0.44 is highly significant (p-value = 2.3 × 10 -4 ).

Water regime under salt stress and QuitoMax application The differences in the water potentials of the varieties in the different treatments were highly significant [F = 108.5; p = 0.00023, F = 112.46; p = 0.000321 for Amalia and Claudia, respectively (Fig. 2 a and b)], and a similar response was found for the osmotic potential (F = 207.32; p = 0.00461, F = 201.31; p = 0.00117 for Amalia and Claudia, respectively).