“highly significant”

Peak horizontal force analysis revealed a highly significant group × time interaction (F (3,43) = 19.407, P < 0.001, η 2 p = 0.58 for peak force; F (3,43) = 7.005, P < 0.001, η 2 p = 0.33 for average force; Table 4 ).

The GLM revealed highly significant effects of organic matter duration on TC accumulation ( F = 30.23, p < 0.001), with crop type showing a secondary influence ( F = 6.55, p < 0.05; Supplementary Table S1 ).

The postoperative change in sphere, cylinder, and SE was highly significant in the two groups ( p < 0.001).

The QOS was good in just 1.4%, whereas it was poor in 81.4%, in the presence of any psychiatric disorder, with the difference being highly significant ( P < 0.001).

In a further complete-case sensitivity analysis restricted to patients with complete DEX dosing records ( n = 76), including weight, DEX loading dose, and DEX maintenance dose as covariates, the time ×HR Z -score interaction again remained highly significant [ F (3, 117.3) = 12.16, p < 0.001], while weight, DEX loading dose, and DEX maintenance dose were not significant predictors of the RPP trajectory (all p ≥ 0.63) ( Supplementary Text S2 ).

Highly significant correlations also occurred between MT protein and MT-2 transcript (not shown) in both the liver ( p < 0.001, r = 0.924) and kidney ( p < 0.001, r = 0.883).

Experimental data are presented as ± SEM, with p < 0.05 indicating significant differences, p < 0.01 indicating highly significant differences, and p < 0.001 indicating extremely significant differences.

After rigorously controlling for these significant demographic and clinical variables, the indirect pathway from childhood maltreatment to suicidal ideation through difficulties in emotion regulation remained highly significant ( p < 0.001), providing robust evidence for the stability of this mediating mechanism across different clinical contexts.

This initial association remained highly significant after adjustment for demographic characteristics in Model 2, though the effect size was modestly attenuated to an OR of 1.43 (95% CI: 1.17–1.75, P < 0.001), accompanied by a substantial improvement in model fit as evidenced by AIC reduction from 4523.6 to 3842.5.

Overall, the canonical axes were highly significant for both vertebrates (Monte Carlo permutation test: F (8,21) = 1.50, p < 0.001) and spermatophytes (Monte Carlo permutation test: F (8,21) = 2.04, p < 0.001).

The Friedman test indicated a highly significant overall time effect (χ2 (2) = 43.46, p < 0.001), with a large within-subject effect size (Kendall’s W = 0.639).

This difference between the APOE4 and the APOE3 cells is highly significant ( p < 0.001).

Sentinel-2 exhibited the highest correlation ( r = 0.46) with high statistical significance ( p < 0.001), followed by Landsat-8 which has 0.42 correlation with highly significant value ( p < 0.001).

HMO-induced expansion of Phocaeicola and reductions in Lacrimispora is associated with reduced faecal acetate and butyrate levels A highly significant negative correlation was found between the relative abundance of Phocaeicola and Lacrimispora (Fig. 7A , Rho = −0.614 , P < .001, Spearman's rank correlation).

These changes represented large effect sizes (Cohen's d = 3.43 and 3.36), and both differences were highly significant ( P < .001).

Results Trait analysis Effects of years and locations were highly significant ( p < 0.001) for all traits evaluated in multiple locations (data not shown).

Although the correlations for the individual substrates are mostly not statistically significant due to the small number of samples, the overall correlation for all six substrates is highly significant ( P = 10 -3 ).

Concerning the temperature, highly significant differences (P < 0.001) were observed at 10 weeks and for the whole experimental period (4 to 10 weeks), body weight being higher at the lower temperature.

The 100 μmol/L apigenin treatment led to a substantial and highly significant (P < 0.001) increase in sperm membrane integrity compared to control, improving from 40% integrity in control to 68% integrity with 100 μmol/L apigenin (Fig. 3 a).

The difference was highly significant in both SM→AM and SM→MM comparisons ( p < 0.001).

Two-way ANOVA confirmed highly significant main effects of both sample type (F = 28.4–52.3, p < 0.001) and functional zone type (F = 18.6–35.2, p < 0.001) on all metal concentrations, with significant interactions for Pb, Cu, Zn, and Cr ( p < 0.05) indicating that enrichment patterns varied among functional zones ( Table 3 ).

6 , we can conclude the following: There was a moderate negative correlation between the percentage of opened dentinal tubules and the weight% of F Wt % in groups SDF, SDF diode 1 W, SDF Nd 3 s, and SDF Nd 5 s, and these correlations were statistically significant (P-value < 0.05) in SDF and SDF diode 1 W and highly significant in SDF Nd 3 s and SDF Nd 5 s (P-value < 0.001).

The analysis revealed a highly significant improvement ( p < 0.001), with a mean reduction of 32.8 s and a 95% confidence interval (CI) of [29.0, 36.6] s.

Key population genetic differentiation parameters showed a highly significant genetic differentiation coefficient ( Fst ) of 0.21 ( p < 0.001) among populations, indicating a moderate level of genetic differentiation across geographic origins.

The increase in incidence rate among women was highly significant when comparing the three age groups (p < 0.001).