Extreme dippers had a lower pulsatility index compared to dippers but just failed to reach statistical significance with the adjusted alpha value in Model 2 and 3 (p= 0.018) (see supplement Table S8 for non-significant associations with dipping patterns).
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Although, CF covered a higher proportion of their overall distance covered in-possession compared to CB, WD, DM, this just failed to reach statistical significance (40% vs 37–38%; P > 0.05; ES: 0.3–0.4).
When considering self‐reported refusal rates, pharmacists in WA appeared the least likely to refuse supply, though when examined in experimental vignettes, the likelihood was also less compared to Victoria, however, just failed to reach statistical significance ( p = 0.051).
Migration was significantly inhibited by CXCL17 (24–119) and a trend toward inhibition with the SUMO3-CXCL17 construct was observed, although this just failed to reach statistical significance ( p = 0.0518).
Social presence condition just failed to reach statistical significance, p = .052, η 2 p = 0.03.
All but 4/5 (80%) patients ≤2 years of age developed disease progression, compared with 15/32 (46.9%) > 2 years of age, however, this just failed to reach statistical significance (p=0.053).
Lipid intake was higher during each of the first four weeks in the PCHO group compared to the HCHO group ( p < 0.05), while the difference between groups just failed to reach statistical significance in the fifth week ( p = 0.053).
Conversely, children with two or more older siblings (aRRR 2.31; 95% CI 0.98–5.43) were at greater risk of following trajectory 3 compared to children with no older siblings, although this association just failed to reach statistical significance ( p = 0.055).
Discussion In this study, we noted that telomere length in diploid cells was increased in females in childhood when compared to males although the difference for the term group just failed to reach statistical significance (p = 0.056); increased in those with IUGR when compared to those without IUGR; and was increased in those in the least socioeconomically deprived group when compared to the most deprived group.
A higher proportion of male patients had increased troponin levels, although this difference just failed to reach statistical significance ( p = 0.059).
The three-way interaction between frequency, SFOAE method, and age was similar, but just failed to reach statistical significance (estimate = 0.0001 [ SEM = 0.00] , p = 0.06).
Endoscopists with average inspection times of >1 min per centimeter of Barrett’s mucosa had higher detection rates of endoscopically suspicious lesions (54.2% vs 13.3%, P=0.04) but the difference in rates of HGD/early esophageal adenocarcinoma just failed to reach statistical significance (40.2% vs 6.7%, P =0.06).
Males were approximately 1.8 times more likely to use cannabis compared to females although this just failed to reach statistical significance (Males n = 27; Females n = 15, χ 2 = 3.4, df 1, p = 0.06).
In general, CTO cases had higher scores on measures of coercion ( Pridham et al., 2016 ), although this only just failed to reach statistical significance in one meta-analysis of two studies ( p = 0.06) ( Kisely et al., 2017 ).
After three days, for the first CT1 mutant line ( SLC6A8 Δex10-11/y ), we observed a 3.5-fold increase in intracellular creatine although this increase just failed to reach statistical significance ( Fig 4C , 4.2 vs 1.2 nmoles/mg protein relative to empty vector controls, P = 0.061, two-sided t-test).
However, on subgroup analysis when tumours were separated into otherwise low-risk or high-risk PTCs, the presence of TC-PTC by three criteria (2 × and 50%, 3 × and 30%, and 3 × and 50%) was statistically significant in low-risk patients ( p = 0.049, p = 0.004, and p = 0.004, respectively) and the criteria of 2 × and 30% just failed to reach statistical significance ( p = 0.063).
At 6 years after surgery, the estimated freedom from thromboembolic complications was higher in the LAAO group, 96.7 % (95 % CI 95.6–97.9 %) and 95.2 % (95 % CI 93.8–96.6 %) for the LAAO and no LAAO groups, respectively, but the difference just failed to reach statistical significance ( p = 0.063).
On multivariable analysis, the type of implanted mitral valve prosthesis just failed to reach statistical significance (HR, 0.43; 95% CI, 0.18-1.06; P = .067; Supplemental Table 3 ).
TM was associated with a more distal occlusion site in the subgroup of patients with IVT, but this association just failed to reach statistical significance in the total population (aOR 1.68 (0.96 to 2.95), P=0.07).
The difference just failed to reach statistical significance ( t = −1.839; P = 0.071).
From the post hoc tests, there is a trend towards those living with a stoma for one to three years exhibited higher symptoms of psychiatric morbidity symptoms, in comparison to those living with their stoma for over 10 years, these just failed to reach statistical significance ( p = 0.073).
Numerical differences between the two groups that just failed to reach statistical significance were observed for TVF (17.23% vs. 14.66%, p = 0.14) and MACE rates after 5 years (20.11% vs. 16.99%, p = 0.09) (Table 5 and Figs. 3 – 4 ).
Isolation-induced down-regulation of Klf2 just failed to reach statistical significance during our qRT-PCR validation of RNA-Seq data, but Krüppel-like factor 2 (KLF2) activators have anti-inflammatory effects in vascular cells ( Xu et al., 2017 ; Lei et al., 2022 ) and any demonstration of similar properties in brain tissue would still be of potential interest.
One of the most interesting and potentially clinically relevant finding from our study was that lower set‐shifting ability (percentage of perseverative errors) at baseline tended to be associated with a lower reduction in eating disorder pathology (EDE global score) until the 18‐month follow‐up, although this finding just failed to reach statistical significance, which may have been the case due to the low sample size.
Importantly, results were similar between our primary and secondary analyses for associations between MoCA total and RAVLT delayed recall scores and spindle frequency and %-fast; and although the associations between cognitive scores and spindle density and power were no longer significant, similar positive relationships were observed between spindle density and the MoCA total and DSC scores which just failed to reach statistical significance after correcting for the false discovery rate ( q = 0.079 and 0.076, respectively).