Interestingly, we observed that rs4979223 ( P = 0.007), rs4978536 ( P = 0.063, with marginal significance), rs2233914 ( P = 0.039), rs10817464 ( P = 0.006) and rs10759637 ( P = 0.006) showed significantly divergent genotypic distribution between groups with mild or severe thrombocytopenia, some of which remained statistically significant after multiple test correction.
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Impact of RT dose on survival outcomes As for disease-free survival (DFS), multivariate analysis revealed that preoperative CA 19-9 value was the only factor significantly associated with DFS ( p = 0.040, Supplementary Table 1 ), whereas pathologic N stage showed marginal significance ( p = 0.063).
However, there was no significant difference in the age group of < 65 years (1.6%, P -value = .500), and the age group of ≥75 years showed a marginal significance (1.6%, P -value = .063), indicating a possible but not conclusive association.
CD8-C1 also exhibited a reduction with marginal significance ( p = 0.063).
There was also an association in the homozygous CC women’s group, but with marginal significance ( p = 0.063).
Compared with HRW group, the BW of rats in HI group was lower with a marginal significance (p = 0.063) during the four weeks (Fig. 1 B).
Conversely, maltreatment's effect on internalizing problems reached only marginal significance ( b = 0.424, p = .063), with associations primarily reflected in correlated random intercepts ( b = 0.783, p = .025), suggesting stable trait differences rather than causal processes.
In contrast, there was no statistically significant difference between the rapid PAP and black rice extract staining methods ( p =0.974), and marginal significance was found for the difference between black rice extract and SpermBlue ( p =0.063).
No significant difference of CTLA-4 -138 genotypic distribution between subject groups was identified ( P =0.119), while marginal significance was observed in the CTLA-4 -318 allelic distribution ( P= 0.063).
Although some correlations approached marginal significance (e.g., CHEQ Grip Efficiency and community participation frequency, ρ = − 0.23, p = 0.063; CHEQ Feeling Bothered and community participation frequency, ρ = − 0.21, p = 0.097), none reached the conventional threshold for statistical significance ( p ≤ 0.05).
Moderating effects of genetic variants on stage of illness development for gene expression and protein levels As indicated in Table 2 , for log mRNA expression levels, there was marginal significance of an interaction between the BDNF genotype and illness development stage after adjustments ( p = 0.063).
Finally, when Factor 2 of perfectionism, or maladaptive perfectionism, is introduced into the model, its explanatory power increases, reaching 29.5% but maintaining a marginal significance level ( p = 0.063).
At the same time, the SNV rate of ASXL1 varied among three CPS groups with marginal significance, with the PD-L1-M group not exhibiting SNV of ASXL1 (p=0.063) ( Figure 6B ).
Also, PD-L1 expression tended to correlate with improved survival, but multivariate analysis showed marginal significance (HR = 0.684, 95% CI [0.4581.021], P =0.063, Table 2 ).
There were significant differences in the levels of the virus RNA between titrated virus at 10 -1 TCID 50 and at 10 -2 TCID 50 ( P = 0.001), between titrated virus at 10 -3 TCID 50 and at 10 -4 TCID 50 ( P = 0.046), between titrated virus at 10 -4 TCID 50 and at 10 -5 TCID 50 ( P = 0.014) except those between titrated virus at 10 -2 TCID 50 and at 10 -3 TCID 50 which showed a marginal significance ( P = 0.063).
In the stroke cohort, the interaction patterns were similar, with statistical significance achieved in Models 1 and 3 (Model 1 p=0.043; Model 3 p=0.047) and marginal significance in Model 2 (p=0.063).
The marginal significance at M3 ( p = 0.063), though not strong, may indicate a trend worthy of further investigation and could have clinical implications for the management of transplant patients concerning SARS-CoV-2 infection.
5.8, p = 0.03) and marginal significance for the Anhui strain (21.6 vs. 8.3, p = 0.063).
The overall CVAE in a group of female patients with breast cancer who had exposure to CDK4/6 inhibitors was slightly higher than for those treated with anthracyclines, with marginal significance (35.9 versus 28.5 per 100 person‐years; P =0.063; Table 2 ); however, there was no statistical difference between these 2 groups in the competing risk analysis (Figure 2A ).
~46–50%), but at the marginal significance ( p = 0.063) (when we consider the US recommendations of 0.80 g/kg body mass, it was, respectively, ~60% vs. ~45%, p = 0.045).
For miR-150-5p, this tendency was noted with marginal significance (27.3% vs. 13.5%; P = 0.063).
Two studies demonstrated improved response times on Go/No-Go ( Ando et al., 2013 ) or ANT tasks ( Huertas et al., 2011 [marginal significance: p < 0.063]).
Multivariate analysis adjusted for age, sex, race, and surgery severity showed that before surgery blood glucose may be an independent predictor of mortality with marginal significance ( P = 0.063) and likewise with postoperative blood glucose concentration ( P = 0.087).
showed a trendp = 0.063
Similarly, the Radiation Therapy Oncology Group (RTOG) #9501 trial showed a trend toward improved OS rates, albeit with marginal significance (OS rate of 42% with adjuvant CRT, compared to 31% with RT alone, p = 0.063).
It was estimated that the disease-free survival was different according to the preoperative PNI with a marginal significance [≤48.85: 21.75 months (95% CI, 19.03−24.4) vs. >48.85: 51.88 months (95% CI, 43.10−60.66), p = 0.0633, Fig 2A ].