Effects of VNS on behavioral responses (detection thresholds and intensity of perception) Changes in skin temperature showed a weakly significant positive correlation to changes in heat-sensitive C-fibers detection threshold (p < .000, R 2 = 0.135), a moderately significant positive correlation with the detection threshold of cool-sensitive free nerve endings (p < .000, R 2 = 0.545), and a weakly significant negative correlation with mechano-sensitive Aβ-fiber detection threshold (p < .000, R 2 = 0.163).
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In the literature
[ 45 ], in the meta-analysis based on 26 RCTs (2652 women), showed a moderately significant effect of isoflavones on bone loss in estrogen-deficient women (WMD (g/cm 2 ) in LS 0.01 (95% CI: 0.01, 0.02), p < 0.000 and in TH 0.001 (95%: CI 0.00, 0.02), p < 0.01).
A moderately significant relationship existed between the PCL-5 total score and pessimism schema (r = 0.463, p = 0.000) ( Table 2 ).
A noticeable, moderately significant lead (cross-correlation: r (10) = 0.65, SE = 0.24, P < 0.00) was found between flowering and rainfall at position 1 in Table 3 , suggesting that flowers increased approximately one month before rainfall increased.
Specifically, the calculation results of the meta-analysis revealed a moderately significant relationship between motivation and loyalty (r = 0.420, 95%CI = [0.321–0.505], p<0.000) with 16 observations.
The most significant positive association was found between FEC and IgA measured in the nasal secretions of young ewes using both antigens (Rho = 0.5; p = 0.00); the correlation of FEC with IgA in serum was moderately significant (Rho = 0.306; p = 0.00).
A moderately significant association of smoking with PCSK-9 use was determined ( p = 0.00).
After controlling for the two factors of bone grafting and RBH, partial correlation analysis showed a moderately significant correlation between the ESBG and IPL, with a partial correlation coefficient of 0.560 (P=0.000).
VAS and DHS L4-L5 MRI findings were evaluated according to physical activity level, and a moderately significant result was determined only for sedentary individuals ( r = 0.45, p = 0.00).
There was even a moderately significant correlation between parental economic distress and the BAS ( r = .44, P = .00).
Within these 47 regions, we also assessed whether the traits that did not have a variant with p < 5 x 10 − 8 , had a moderately significant variant with p < 1 x 10 − 6 ; signals from such traits were also included in our fine-mapping.
Twenty-five additional independent loci showed moderately significant ( P < 1 × 10 −6 ) associations, nine with endometrial cancer overall, nine specifically with endometrioid histology, and seven with non-endometrioid histology (Supplementary Data 2 ).
Finally, GWAS from the CARDIOGRAM Plus consortium 23 identified a moderately significant association between a SNP overlapping the TCONS00016111 transcript and human coronary artery disease (P=4.78E–6) ( Fig. 6g ).
The identification of moderately significant (10 −2 >p>10 −5 ) SNPs offers a novel method for detecting the “missing heritability” of hypertension.
Recently, a meta-analysis study of our group examined the effect size of depressive symptom in 1,159 schizophrenic patients, which showed that patients showed moderately significant effects in favor of mind-body exercise intervention to improve depression (SMD = 0.88; 95% CI 0.63–1.13; p < 0.00001) [ 24 ]. 2.2.
The next 2 genes (low density lipoprotein receptor ( LDLR ) and tissue inhibitor of metalloproteinases metallopeptidase inhibitor 1 ( TIMP1 ) showed moderately significant upregulation (p < 1 × 10 −5 ) in gene expression between D20+ TGF-β and D20 samples, as detected by RNASeq analysis and a significant upregulation at D20+ TGF-β vs D20 by real-time PCR (Fig. 4H,I ).
After correcting for age at recruitment, population structure, and study site, we identified 266 moderately significant associations, 51 of which were independent ( p < 10 −5 , r 2 < 0.2).
Linkage disequilibrium and haplotype analysis The LD test revealed that LD was moderately significant between T182C and A3081T (|D'|=0.702, r 2 =0.275, p-value=<10 -5 ) but not between A3081T and G1287A or between T182C and G1287A ( Table 5 ).
Additionally, the Arg460Gly variant independently showed a moderately significant protective association with the heavy smoker phenotype (OR = 0.56; CI = 0.43–0.72; P = 1.1 × 10 −5 ).
(iii) Most of the disease LD blocks (67 %) included a single moderately significant disease-trait-associated marker (3E-08 < P < 3.3E-05).
Moreover, 138 and 176 SNPs were found to have suggestive (moderately significant) association with RFI1 and RFI2 at p < 5 × 10 -5 , of which 124 SNPs have been found to be associated with both traits.
The association findings for these three genes using other methods (O’Brien with GATES and TATES with GATES) are also moderately significant ( P < 7.0 × 10 −5 ), except for MultiPhen with GATES ( P < 0.01).
One study reported a significant difference (MD: 25; 95% CI: 18.16–31.83; P = 0.0001), 27 , 30 and another found a moderately significant benefit (MD: 10.2; 95% CI: 5.91–14.48; P = 0.0001). 27 , 30 Two studies showed no significant differences ( P = 0.1622 and P = 0.2223, respectively). 26 , 36 Physical Well-being of the Chest The results were heterogeneous.
In addition, Spearman’s correlation analysis showed a moderately significant association between 2-methylbutyric acid and CHD development ( r = 0.5037, p = 0.0001).
There were moderately significant positive correlations between VF and MAF [right eye (r s = 0.631, p = 0.0001), left eye (r s = 0.633, p = 0.0001)] and BAF (r s = 0.580, p = 0.0001). 4.