“modest significance”

Among them, Cluster-3 is of our special interest because ∼95% of patients in this group have mutated TP53 gene and its survival profile is poorer than that of the other clusters with a modest significance ( P = 0.07, logRank test).

Correlations between RF-predicted and real patient survival on held-out samples were in the range of 0.12 to 0.35 for six TCGA cohorts (Additional file 1 : Figure S9) with corresponding modest significance ( p <0.1) for acute myeloid leukemia (AML) and skin cutaneous melanoma (SKCM), and stronger significance ( p <0.013) for head and neck squamous cell carcinoma (HNSC), glioblastoma multiforme (GBM), lung adenocarcinoma (LUAD), and ovarian serous cystadenocarcinoma (OV).

A second measure of demand generation—exposure to family planning messages in the media at the community level—did not have the expected relationship in the multivariate model, only reaching modest significance (p < .10) in Burkina Faso, Uganda, and Kenya with regard to short-acting contraceptive use and Ghana with regard to long-acting method use.

In addition, the humidity of indoor air was lower in houses with AD children than in houses without AD children, with modest significance ( p < 0.1).

The cluster with higher expression had a better overall survival rate however with a modest significance ( p = 0.14 for METABRIC, p = 0.13 for GSE58812 ).

Variables that were associated with either sleepiness or breastfeeding at a modest significance level ( p < 0.2) were included as covariates in subsequent multivariate analyses.

19.1%; P < 0.050; adjusted OR, 1.47; 95% CI, 0.99–2.16), with modest significance, and with a significance in the 26–28w GA subgroup.

Only modest significance was found in the acquisition of health information for the health literacy dimension, and possible explanations did not have sufficient statistical power to identify any health literacy effects in this cross-sectional survey or imply that other factors or pathways need to be explored in further research.

Significant inverse association was observed between total plasma carotenoid concentrations and oxidative stress measured by urinary 8-hydroxy-2’-deoxyguanosine (8-OHdG) while only modest significance was shown for 8-iso-prostaglandin F2α (8-iso-PGF2α).

The pro-inflammatory skewed cytokines (IL-10, IL-1β, IL-6, and KC/GRO) indicated modest significance between groups in favor of high dose PfCSP mRNA-LNP1 formulation (Supplementary Fig. 2 ).

However, it is important to point out the modest significance of the results, especially in view of the small number of cases.

They found that there was no significant relationship between BMI and orthorexia for physiotherapy students, whilst the dietetic students demonstrated modest significance, with higher BMIs being associated with a higher degree of orthorexia prevalence.

In BRCA, clustering on all variables yields no significant separation ( P = 0.28), while SPLS and the CCA‐based methods achieve modest significance only when using all 5 components (SPLS: P = ; PMDCCA: P = ; RGCCA: P = ) but fail when restricted to their selected features.

However, CD2 co-stimulation could increase CD16-triggered responses also in the NKG2C − CD57 + subset (both FcεRγ + and FcεRγ neg ) although a modest significance was reached only in NKG2C − CD57 + FcεRγ pos cells (Figure 6 C), although CD2 expression levels were lower than those found in NKG2C + NK cells (Figure 4 ; Figure S4B in Supplementary Material).

The six LA scores listed at Table 4 show only a modest significance individually, but collectively they are significant with p-value of 0.0064.

Of the 18 novel SNPs, 10 SNPs were replicated, albeit at a more modest significance level, in at least one of the other subtypes.

dataset, we also found that CG-1 and CG-2 tumors were more likely to experience biochemical relapse over a 5-year period relative to A-Low tumors, although at modest significance ( Supplementary Figure S3 ).

Conflicting reports have been published for the association of telomere length with renal disease, however, most publications, albeit in relatively small sample sizes with modest significance values, report that shorter telomere length is associated with renal dysfunction.

Tumors with loss of the other miRNAs showed a modest significance for this region (hsa-mir-137; Fig. 6 B ) or no significance (hsa-mir-23b; data not shown).

Across the three comparisons, we observed downregulation of processes related to ‘extracellular matrix organization’ and ‘cell adhesion’, although these terms reached only modest significance in our cohort, likely due to the narrower focus on DT-G1 meningiomas.

Correlation Analysis A correlation analysis was first developed using all metabolites to bring up relationships; however, those between hydrosoluble and liposoluble fractions were of modest significance.

By contrast, 3’SS in general did not appear to play a major role in intronic C/P in the samples analyzed in this study, except for some modest significance for the last introns containing upregulated pAs by siSF3b155 and siU2AF65 ( Fig 3D ).

The Leu7Pro polymorphism correlated inversely with the presence of CAD and the occurrence of myocardial infarction in our cohorts, although these associations were of modest significance.

The modest significance level might be due to the low number of matching groups.

It is possible that several loci of modest significance remain to be discovered due to the complex, syndromic nature of SLE, along with other GWAS limitations.