However, there are several SNVs more significantly associated with PPP2R2B expression in eQTLGen, and these have only modest significance in the GeM-GWAS ( p -values of ~0.07, see Supplementary Data).
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“modest significance”
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p=0.082
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Among them, Cluster-3 is of our special interest because ∼95% of patients in this group have mutated TP53 gene and its survival profile is poorer than that of the other clusters with a modest significance ( P = 0.07, logRank test).
In addition, the humidity of indoor air was lower in houses with AD children than in houses without AD children, with modest significance ( p < 0.1).
A second measure of demand generation—exposure to family planning messages in the media at the community level—did not have the expected relationship in the multivariate model, only reaching modest significance (p < .10) in Burkina Faso, Uganda, and Kenya with regard to short-acting contraceptive use and Ghana with regard to long-acting method use.
Correlations between RF-predicted and real patient survival on held-out samples were in the range of 0.12 to 0.35 for six TCGA cohorts (Additional file 1 : Figure S9) with corresponding modest significance ( p <0.1) for acute myeloid leukemia (AML) and skin cutaneous melanoma (SKCM), and stronger significance ( p <0.013) for head and neck squamous cell carcinoma (HNSC), glioblastoma multiforme (GBM), lung adenocarcinoma (LUAD), and ovarian serous cystadenocarcinoma (OV).
The cluster with higher expression had a better overall survival rate however with a modest significance ( p = 0.14 for METABRIC, p = 0.13 for GSE58812 ).
Variables that were associated with either sleepiness or breastfeeding at a modest significance level ( p < 0.2) were included as covariates in subsequent multivariate analyses.
Modest significance was identified during sensitivity analyses for the Parker mobility score and the Harris hip score favoring the IMN.
The updated interactomes, integrating the latest genetic findings of PD and SZ, recapitulated the groups of genes following the temporal profiles and disease affiliations of DGN2 and DGN3 with high significance and that of DGN1 with modest significance (Supplementary Note S 7 and Supplementary Fig.
Same way the test results for patient background yielded a P value of .04 (2-tailed) with U of 1732 and a mean rank of 64.18 for novices and 76.42 for experts, suggesting a statistically significant difference between the 2 groups, albeit with a modest significance level.
The role of structural variables exerts a constructive impact on bridging the financial depth gap, albeit with modest significance.
A modest significance in sex was observed with the males having longer colon lengths than females.
Correlation Analysis A correlation analysis was first developed using all metabolites to bring up relationships; however, those between hydrosoluble and liposoluble fractions were of modest significance.
The significant increase in mice eliminated the modest significance seen in our previous publication ( 8 ).
Furthermore, compared with SSCVs identified by juncmut, the variant chosen by SpliceAI 23 , a machine learning-based splicing effect predictor, showed modest significance (Fig. 1e , see “Methods” section for details).
However, it should be noted that the interaction effects of interest were of modest significance (i.e., just below the 0.05 threshold).
Moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions With regards to the moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions (see Table 7 ), eight moderations were observed – in line with theory – albeit mostly with modest significance levels, except for that of perceived competence strengthening the negative relationship between future time perspective and implemental delay.
The results show modest significance, with AUC values ranging from 0.6 to 0.7, and accuracy ranging from 70% to 72%.
Power to detect true association for disease prevalence of 11%, risk allele frequency of 20% and relative risk of 1.5 at a modest significance level of 0.05 was 0.9 ( http://csg.sph.umich.edu/abecasis/gas_power_calculator/index.html ).
Motivations: Professional versus Jury-Determined Standards Before delving into those specifics, I step back to reflect on why Stewart and Peck appear this concerned about a provision that, by most accounts, addresses a technical issue of only modest significance.
2013 ), which may explain the modest significance level for some of our results.
Notably, our small sample size may lead to modest significance levels, thus large-scale prospective studies are needed to better assess potential associations between clinical characteristics and trends in HbA1c and DEB among adolescents with T1D following the implementation of insulin pump therapy.
Across the three comparisons, we observed downregulation of processes related to ‘extracellular matrix organization’ and ‘cell adhesion’, although these terms reached only modest significance in our cohort, likely due to the narrower focus on DT-G1 meningiomas.
In practice, this can be interpreted as FOC having modest significance in explaining the association to life satisfaction or health-related quality of life in older adults.
Therefore, our results, especially for factors with modest significance levels, should be considered hypothesis-generating rather than definitive.