“modest significance”

Also, noting at least once that such results yielded modest significance would give a transparent and clear image of the present work. 2) The manuscript's discussion section, similar to the introduction and results in the earlier version, suffers from a disordered flow of ideas.

Although no associations with genome-wide significance were detected, two associations with modest significance were reported. rs500766 (g.6508628C>T) in protein kinase C theta ( PRKCQ ) was found to decrease the risk of ACEIs-AE if the patient carries at least one copy of the alternative allele.

Moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions With regards to the moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions (see Table 7 ), eight moderations were observed – in line with theory – albeit mostly with modest significance levels, except for that of perceived competence strengthening the negative relationship between future time perspective and implemental delay.

The significant increase in mice eliminated the modest significance seen in our previous publication ( 8 ).

The updated interactomes, integrating the latest genetic findings of PD and SZ, recapitulated the groups of genes following the temporal profiles and disease affiliations of DGN2 and DGN3 with high significance and that of DGN1 with modest significance (Supplementary Note S 7 and Supplementary Fig.

Despite the inherent limitations and the modest significance of our findings, we believe that our study provides plausible biological insights that might further the understanding of immune contributions to BP.

Remarkably, these genes exhibit significant importance in PheSeq analysis, despite showing relatively modest significance in sequence analysis.

dataset, we also found that CG-1 and CG-2 tumors were more likely to experience biochemical relapse over a 5-year period relative to A-Low tumors, although at modest significance ( Supplementary Figure S3 ).

In contrast, it showed modest significance in 3-month period (RR = 1.37, 95%CI = 1.06–1.75, I 2 = 98%, 5 studies, 4058 studies) ( S7 Fig ), 6-months (RR = 1.37, 95%CI = 1.03–1.83, I 2 = 99%, 9 studies, 8303 participants) ( S8 Fig ), 12 months (RR = 1.46, 95%CI = 1.17–1.82, I 2 = 98%, 10 studies, 8438 participants) ( S9 Fig ).

Betweenness centrality derived from AECs also shows marked increases within the SOZ in the gamma frequency band, but corresponding Z-scores relative to permutation test distributions only reach modest significance in the gamma band.

They found that there was no significant relationship between BMI and orthorexia for physiotherapy students, whilst the dietetic students demonstrated modest significance, with higher BMIs being associated with a higher degree of orthorexia prevalence.

However, it should be noted that the interaction effects of interest were of modest significance (i.e., just below the 0.05 threshold).

Furthermore, compared with SSCVs identified by juncmut, the variant chosen by SpliceAI 23 , a machine learning-based splicing effect predictor, showed modest significance (Fig. 1e , see “Methods” section for details).

Correlation Analysis A correlation analysis was first developed using all metabolites to bring up relationships; however, those between hydrosoluble and liposoluble fractions were of modest significance.

A modest significance in sex was observed with the males having longer colon lengths than females.

Same way the test results for patient background yielded a P value of .04 (2-tailed) with U of 1732 and a mean rank of 64.18 for novices and 76.42 for experts, suggesting a statistically significant difference between the 2 groups, albeit with a modest significance level.

Modest significance was identified during sensitivity analyses for the Parker mobility score and the Harris hip score favoring the IMN.

Interestingly, however, G114E did rescue docking with modest significance, and notably, D184W elicited a highly significant rescue of BB depth compared to knockdown (Fig. 4F–H ).

Given these limitations, as well as the modest significance of our findings, the implications of the mentalization network in subclinical participants warrant further investigation in future studies. 4.3 The central execution network While the IC7 mostly overlaps with the DMN, some portions of the dlPFC and IFG, are usually ascribed to the CEN.

Prior studies examining HSP90α in plasma of patients with COPD ( 35 ) demonstrated an increase with disease severity of modest significance, suggesting that HSP90 levels may not be as sensitive and specific for disease.

In BRCA, clustering on all variables yields no significant separation ( P = 0.28), while SPLS and the CCA‐based methods achieve modest significance only when using all 5 components (SPLS: P = ; PMDCCA: P = ; RGCCA: P = ) but fail when restricted to their selected features.

IL4-Beva significantly increased the number of B cells that took up VEGF-647 (mean 19.4%), of modest significance above all other treatments.

For instance, we utilized GWAS p -values or fine mapping posterior probabilities: a gene with a very significant association or high causal probability would receive a larger weight α G than a gene with modest significance.

In addition, the strength of association is characterized by large coefficient interval and modest significance.

Heart disease (14.3% vs 4.9%, p = 0.063) and pneumonia noted by the admitting clinician (9.7% vs 4.1%, p = 0.054) modest significance.