Representative maps of the pathways that showed modest significance and were included in Table 1 and Supplementary Table S11 , available at Carcinogenesis Online, such as ‘E-cadherin signaling and its regulation in gastric cancer (FDR = 0.004 and P < 0.001 for Cluster B1)’ and ‘Development_Regulation of EMT (FDR = 0.002 and P < 0.001 for Cluster B1)’, are illustrated schematically in Figure 4 using MetaCore software.
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p=0.082
In the literature
Conflicting reports have been published for the association of telomere length with renal disease, however, most publications, albeit in relatively small sample sizes with modest significance values, report that shorter telomere length is associated with renal dysfunction.
The six LA scores listed at Table 4 show only a modest significance individually, but collectively they are significant with p-value of 0.0064.
They found that there was no significant relationship between BMI and orthorexia for physiotherapy students, whilst the dietetic students demonstrated modest significance, with higher BMIs being associated with a higher degree of orthorexia prevalence.
Significant inverse association was observed between total plasma carotenoid concentrations and oxidative stress measured by urinary 8-hydroxy-2’-deoxyguanosine (8-OHdG) while only modest significance was shown for 8-iso-prostaglandin F2α (8-iso-PGF2α).
Despite the inherent limitations and the modest significance of our findings, we believe that our study provides plausible biological insights that might further the understanding of immune contributions to BP.
In contrast, it showed modest significance in 3-month period (RR = 1.37, 95%CI = 1.06–1.75, I 2 = 98%, 5 studies, 4058 studies) ( S7 Fig ), 6-months (RR = 1.37, 95%CI = 1.03–1.83, I 2 = 99%, 9 studies, 8303 participants) ( S8 Fig ), 12 months (RR = 1.46, 95%CI = 1.17–1.82, I 2 = 98%, 10 studies, 8438 participants) ( S9 Fig ).
Moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions With regards to the moderating role of psychological need satisfaction on the relationships between time perspectives and procrastination dimensions (see Table 7 ), eight moderations were observed – in line with theory – albeit mostly with modest significance levels, except for that of perceived competence strengthening the negative relationship between future time perspective and implemental delay.
A follow-up study in another independent sample of schizophrenia cases and controls from the Ashkenazi Jewish population replicated the women-specific association with schizophrenia of rs7341475, although with very modest significance [27] .
In addition, the strength of association is characterized by large coefficient interval and modest significance.
dataset, we also found that CG-1 and CG-2 tumors were more likely to experience biochemical relapse over a 5-year period relative to A-Low tumors, although at modest significance ( Supplementary Figure S3 ).
Of the 18 novel SNPs, 10 SNPs were replicated, albeit at a more modest significance level, in at least one of the other subtypes.
However, CD2 co-stimulation could increase CD16-triggered responses also in the NKG2C − CD57 + subset (both FcεRγ + and FcεRγ neg ) although a modest significance was reached only in NKG2C − CD57 + FcεRγ pos cells (Figure 6 C), although CD2 expression levels were lower than those found in NKG2C + NK cells (Figure 4 ; Figure S4B in Supplementary Material).
However, it is important to point out the modest significance of the results, especially in view of the small number of cases.
The pro-inflammatory skewed cytokines (IL-10, IL-1β, IL-6, and KC/GRO) indicated modest significance between groups in favor of high dose PfCSP mRNA-LNP1 formulation (Supplementary Fig. 2 ).
Only modest significance was found in the acquisition of health information for the health literacy dimension, and possible explanations did not have sufficient statistical power to identify any health literacy effects in this cross-sectional survey or imply that other factors or pathways need to be explored in further research.
19.1%; P < 0.050; adjusted OR, 1.47; 95% CI, 0.99–2.16), with modest significance, and with a significance in the 26–28w GA subgroup.
After adjusting for missing storms, the century-scale decrease in USA-striking HU fraction is weaker and of modest significance, largely reflecting the influence of a maximum in the 1910s (Fig. 3 ).
More modest significance levels were seen at 13q32 (rs7982677) in intron 7 of GPC5 and the non-synonymous substitution Ile733Val in NRP1 [ 33 ].
The updated interactomes, integrating the latest genetic findings of PD and SZ, recapitulated the groups of genes following the temporal profiles and disease affiliations of DGN2 and DGN3 with high significance and that of DGN1 with modest significance (Supplementary Note S 7 and Supplementary Fig.
The first of these came from a small cohort of children, where slight differences in DNA methylation patterns within the protocadherin (PCDH) gene clusters reported with a rather modest significance threshold [ 35 ].
An example of such an analysis is [ 7 ], which showed a highly significant difference in survival with a much more modest significance level for a comparison of 30 day mortality.
Prior studies examining HSP90α in plasma of patients with COPD ( 35 ) demonstrated an increase with disease severity of modest significance, suggesting that HSP90 levels may not be as sensitive and specific for disease.
32 – 33 The variables nominally associated with the MAPK14 variants within the dyslipidemia subgroup need to be interpreted with caution due to the modest significance levels and small number of carriers, but are provided for descriptive purposes.