“near-significant”

HC also shows a near-significant increase in protein intake despite not reaching a daily protein intake of 60 g per day.

Hybridisation was negatively associated with age but positively correlated with the number of listed plants and their reported uses, while multilingualism showed a near-significant positive trend.

Skin temperature was markedly increased in the hot and decreased in the cold environment, and MDMA produced a near-significant increase in skin temperature under both temperature conditions and compared with placebo. 50 Altogether, considering the pooled data analyses from our laboratory and those of the Freedman study, MDMA is well documented to produce an acute and dose-dependent elevation in core body temperature in healthy subjects.

In summary, univariate analysis highlights widowed marital status, certain blood groups, obesity, pregnancy, elevated body temperature, and RBS as significant or near-significant predictors of mortality among COVID-19 patients.

Therefore, we described it as a ‘near-significant’ observation, emphasizing that confirmation requires larger, prospective studies with greater statistical power.

Functional connectivity within DM-SNs In FC analysis with normal ICA / dual-regression procedure, neither significant nor even near-significant group differences were detected on any model order for the DM-SNs.

Specifically, a positive correlation was observed between pain magnification and the neurometabolites Gln and Glx, as well as the near-significant neurometabolites NAA and NAA + NAAG ( Figure 3 and Supplementary Table 3 ).

MRI signal changes showed a near-significant association with prolonged symptom duration, suggesting osseous and soft tissue abnormalities may contribute to symptom persistence.

Follow-up comparisons within the left IFG cluster showed a near-significant priming effect in the higher predictive validity blocks (Z = 2.67, p FWE = 0.054).

The results indicate that CUT significantly influences WSA, WESA, and LSA, with all demonstrating large effect sizes; however, regarding comfort factors, only NLCV (WS) showed near-significant differences.

Greater variance was explained by BRIEF BRI Inhibit in the CYA-SCD-SCI+ (22%, p = 0.058), although near-significant. 4.

This near-significant result points to the complexity of P. polycephalum ’s adaptive mechanisms, where even closely related stress responses may manifest differently at the structural level. 2.3.

However, three supplementation studies reported significant or near-significant reductions in systolic blood pressure [ 76 , 77 , 78 ].

When a stepwise model was run with only significant or near-significant factors entered into the model (SEPP1 was excluded as it was highly associated with treatment: mean 5·13 v . 2·95 mg/l for the Se-treated and placebo groups, respectively, P < 0·0005), baseline DBP (OR 1·10, 95 % CI 1·03, 1·18), BMI (OR 1·13, 95 % CI 1·00, 1·27) and toenail Se concentration (OR 0·38, 95 % CI 0·17, 0·87) remained significant, with treatment again failing to reach significance ( P = 0·067) (adjusted model 1; Table 3 ).

[ 204 ] clearly demonstrated a statistically significant or near-significant reduction in IL-23, TNF-α, and IL-17F, along with a notable decrease in the ESR, CRP, PASI, and DLQI scores, supporting the clinical and immunological efficacy of biologic treatments in moderate-to-severe psoriasis.

Notably, the DST results showed a near-significant impact on histopathological malignancy markers (eg, Ki67 index) and the risk of metastases or recurrence, suggesting potential links to tumor aggressiveness that warrant further investigation.

According to our results, a higher dietary sodium-to-potassium ratio was associated with an increase in Lipid Turnover Index (LTI) at a near-significant level.

Post-hoc analysis revealed a near-significant two-fold decrease in MyoD mRNA expression following CE in the untrained state (post-hoc = 0.05), which was reversed following training, resulting in a significant increase compared with the untrained condition (post-hoc p = 0.01).

STH infection was a significant negative predictor of IgG1 galactosylation, and schistosomiasis and CRP level near-significant predictors.

The near-significant p -value for 3-pts score could warrant further investigation with larger samples or more statistical power. 5.

Significance corrections like Bonferroni may be too strict; some of the near-significant pleiotropic associations may, in fact, represent genuine associations.

The UHT group crossed significantly more area boundaries in an open field arena, spent significantly more time in close proximity to a novel object, and had a near-significant tendency to spend more time on the open arms of an elevated plus maze (EPM), compared to controls.

This biphasic modeling indicated a significant increasing trend (before 7 weeks) of both ERR and EAR ( Table 3 , see γ 1 values) and a near-significant decreasing trend (after 7 weeks) of ERR and EAR, respectively ( Table 3 , see γ 2 values).

Higher age, poor adherence and type of TB (smear 3+, smear-negative, or EPTB) are significantly associated with mortality among TB patients, and HIV infection has a near-significant effect.

Nonetheless, all these conditions were associated with a statistically significant, or near-significant, reduction in progression-free survival (PFS) compared to the control (unaltered) group (Fig. 5 B).