“near-significant”

We are well aware of the limitation in the study by having investigated the effect of acute exercise in only six subjects, leaving us in some cases with near-significant trends.

However, the titer of just one metabolite, 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), displayed near-significant enrichment in Hamiltonella -positive aphids in both metabolome experiments.

However, there was a near-significant effect in the requests subscale, suggesting a possible trend that could be explored with a larger sample size.

(2010) reported differential effects for the total DQ and the VR subscale, with a near-significant effect for the receptive language scale, and differential effects in other measures (i.e.

Among patients subjected to aortic valve and/or aortic surgery, regression analysis showed significant association of fever, C-reactive protein (CRP) elevation between 5 and 100 mg/L, urgent procedure and postoperative antibiotic use with PPS diagnosis, whereas younger age showed near-significant association.

Although no statistically significant difference was found (P = 0.05), the ≥ 120 s stretching subgroup showed a small, near-significant effect, suggesting the need for further investigation.

The near-significant p -value of 0.06 and the weak correlation (r = 0.143) suggests that with a larger sample size or more refined study design, this association might become clearer.

This near-significant finding may reflect a parallel anatomical aging process that did not reach sufficient statistical strength in the current sample.

They found improved NAS, reduced hepatic stellate cells (HSC) activation, and a near-significant decrease in TG and HOMA-IR in patients with VD plus Ca supplementations ( 10 ).

However, we overcame this by including only factors that showed significant or near-significant associations in preliminary bivariate tests.

Diabetes mellitus, a known immune disorder, was also a near-significant risk factor for adverse effects after the first dose.

While some variables displayed directional or near-significant trends, these patterns do not provide evidence of causal mechanisms nor establish that the CD prompt directly influenced underlying psychological processes [ 64 , 65 ].

In addition, IL-6 (p group =0.089) and IL-10 (p group =0.057 and p time×group =0.077) showed a near-significant increase in postprandial expression in the FDRT group.

This near-significant finding may indicate a true underlying association that could be confirmed in larger, powered studies.

Variables were selected for inclusion in the multivariable model based on clinical relevance, prior evidence, and significant or near-significant associations in univariable analysis.

There was a near-significant association between FMD at baseline and disease severity assessed as mild/moderate versus moderate versus moderate/severe (p for trend = 0.051, Fig 2 , panel A), but no significant correlations between FMD and either SF-36 Physical Function (p = 0.60, panel B) or steps per 24 hours (p = 0.22, panel C).

Among these, hypocapnia and acidemia were significant risk factors for the low VR subgroup, and alkalemia showed a near-significant association with 30-day mortality, while hypercapnia was not a significant risk factor for the low VR subgroup.

The 2015–2019 rise, though less pronounced than among females, suggests challenges in high-risk male groups, such as migrant laborers, with the near-significant decline in 2019–2021 indicating partial mitigation efforts. 4 Forecast Results: Projected Age-Standardized prevalence Rates of Latent Tuberculosis infection in South Asia, 2021–2050 Projections of age-standardized prevalence rates (ASPR per 100,000 population) for latent tuberculosis infection (LTBI) in South Asia and its five constituent countries were generated using auto-ARIMA models fitted to Global Burden of Disease (GBD) 2021 historical data from 1990 to 2021, with forecasts extended to 2050 accompanied by 95% prediction intervals (95% PI).

However, even with this reduced power, the QTL map for pA suggests that the genetic architecture for triglyceride level is different between the two mapping panels, as there is no evidence of near-significant peaks in pA within QTL intervals statistically identified in the pB panel (Figure S15).

Donepezil (0.1–1 mg/kg) showed near-significant enhancements in d ′, and EVP-6124 (0.3–3 mg/kg) exerted no effects in the rCPT paradigm.

Variables demonstrating significant or near-significant associations were considered for inclusion in the multivariable model.

A near-significant TstWt at the same marker for GWAS models, MLM, MLMM, and GLM as PHS resistance on chromosome 1B at 382 million base pairs (MBPs) was observed (data not shown).

The near-significant interaction between water type and period suggests that stress may have selectively reduced the appeal of SYN water.

Interestingly, a marker of autophagic EVs, Sequestosome-1 (SQSTM1), was down-regulated at a near-significant level (q-value: 0.017) in the SCZ cell lysates ( Figure S3e ).

We did note, however, the near-significant survival advantage for DNR-90 and IDA-12, in the younger age group, even after adjusting for age and karyotype ( Figure 1B ).