“nearly significant”

The injured gastrocnemius–plantaris complex in the UCHL1 smKO mice had a nearly significant increase in contractile force ( Figure 7 A) when subjected to several different preloads.

In addition, the between-group analysis on craving score difference was nearly significant, and the effect size was 0.58, in favor for a larger effect in the real tDCS group when compared to sham-tDCS.

When separated by treatment, the control groups showed a nearly significant difference in adolescents (p control_7W vs. control_5W = 0.055) and adults (p control_12W vs. control_10W = 0.088), while significant differences were observed in alcohol-exposed adolescents (p Ethanol_7W vs.

In all patients, baseline BCL2 (unfavorable), baseline and Cycle 2 CD8/CNT (favorable), Cycle 2 CD8/INV (favorable; limited sample size), and increases in either CD8/CNT or CD8/INV (favorable; limited sample size) all had significant or nearly significant impacts on pCR.

25 Pizzi and associates observed mixed but largely negative effects of SSRIs on cardiac markers in the UPBEAT study, with nearly significant increases in heart rate variability with sertraline compared with exercise or placebo in the 3‐arm trial, but no change in other markers of inflammation, endothelial and platelet function, or baroreflex sensitivity. 29 Three studies have examined longer‐term effects on major cardiac events.

The fact that IL-5 is involved in fibrosis regulation, coupled with our analyses revealing a nearly significant impact of parasite population on fibrosis, supports this notion [ 65 ].

Interestingly, we found that primiparous mothers seemed to have a nearly significant 2-fold higher risk of seropositivity compared with multiparas, further implicating an underlying autoimmune mechanism as a primary driver of poorer fetal growth.

However, it is not clear whether this region should be considered to include one or two QTL; while it does appear that a valley separates two distinct regions (bp 169,299-1,714,039; bp 11,628,191-15,682,389), the allele frequency differences in this valley are still nearly significant themselves.

Our sensitivity analysis showed, however, that when restricting to population-based controls only, the effect size of heavy alcohol consumption remained similar and nearly significant even with a smaller sample size.

Moreover, these effects are nearly significant throughout an adult's life cycle, although the magnitude is different.

The three ages groups spanning 45-75 yield qik (P) appreciably greater than one and each yields a normal deviate test which is nearly significant.

When a significant ( p < 0.05) or nearly significant (statistically insignificant but with a p value below 0.15) result was found from the full model, it is noted, and results from the simplified models are used to describe the specific effects of the interaction.

Silicate and ammonium had nearly significant p ‐values in different seasons (winter/spring and summer for silicate, fall for ammonium, see Table S5 ).

Significant or nearly significant sex-dependent effects of BC supplementation were found for Klf6 , Vegf , Rora , and Bco1 , as BC supplementation upregulated the expression of these genes in the liver of females but not males.

BDI ( F 1,51 =7.4, P =0.009) and VAS ability to concentrate ( F 1,51 =7.5, P =0.008) were nearly significant ( Figure 2 ).

The negative correlation between the expression levels of CsMYB4a and total catechins was nearly significant ( P -value, 0.08).

The fixed effect of CRP on CCECAI score was nearly significant at Pr > F = 0.06.

15 , 16 Significant (or nearly significant) differences were reported in four studies ( Supplementary Table 3 ). 15 , 17 – 19 Several studies reported burning and taste alteration in CPC patients, 11 , 13 – 15 , 17 , 20 , 21 and only two 15 , 20 reported these side effects in placebo groups.

None of the risk factors significantly contributed to surgical or clinical failure, although female gender and number of concomitant procedures were nearly significant.

Other nearly significant DAPs included potassium voltage-gated channel subfamily C member 1 (KCNC1) with 50% increased abundance and Ras-related C3 botulinum toxin substrate 1 (RAC1) and catenin beta-1 (CTNNB1), each with 12% decreased abundance ( p = 0.021, FDR = 0.6).

On the levels of superfamilies and suborders, these differences were nearly significant (Table 1 , Supplementary Fig.

After removing the two clearly divergent individuals FCant5 and FNZ1, and despite small sample sizes, the difference between FCant and the other two samples was nearly significant for the Mann-Whitney test, although not for the post-hoc Tukey’s test ( Table 2 ).

Age and cardiac status showed a nearly significant impact on GI toxicity ( Table 3 ).

This approach revealed a significant decrease in the CD3 + T-cell population in the lungs of DM mice as compared with their euglycemic cohort and a nearly significant decrease specifically in CD8 + T-cells ( Fig. 3 C ), consistent with the results of the whole lung bulk-RNA seq experiment.

No significant correlation was detected for water- or physiological-based NP size and the cell barrier interactions ( File S3—Figure S1 and File S4—Figures S4–S7 ), although nearly significant correlations were seen between NP size and the 1 and 24 h Caco-2 viability ( Figure 4 f,i).