increased exon inclusion) in heat call-treated embryos, with the enrichment analysis showing a nominally significant difference (proportion of gains=0.24, P =0.049, q =0.34; total exon skipping events=17) ( Table S5 ).
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The only nominally significant between‐group difference was for FNAE ( p = .049), but this was in the opposite direction to that expected under a simple dosage‐effect expectation, with greater improvement observed in the lower‐engagement group.
In addition, the pregnant women carrying the T allele of LPIN1 rs1050800 had a nominally significant 1.169‐fold risk of GDM (95% CI 1.000–1.354, P = 0.049) after adjustment for age compared with the women harboring the C allele.
UPPS‐Lack of Premeditation with an optimal cut‐off of >8 was nominally significant ( P = 0.049), but was associated with exceedingly low sensitivity and NPV (0.24, 0.52, respectively) and classified AUD status with only 56% accuracy.
We identified nominally significant positive GxE effects in the full cohort ( R 2 = 0.08%, p = 0.049) and in women ( R 2 = 0.19%, p = 0.017), but not in men ( R 2 = 0.15%, p = 0.07).
A nominally significant association of DCTN1 PDVs with PD was found in the EoPD & FPD cohort (20 vs. 7, p = 0.049), which did not remain significant after correction (FDR p * = 0.098).
A nominally significant difference in the direction of the preterm preadolescents outperforming the term preadolescents was detected only on Block Construction (F (1,37) = 4.131, p = 0.049), not surviving correction for multiple comparisons.
We identified seven outliers in the analysis of SmkInit and CD risk using the MR-PRESSO approach and the causal association became nominally significant after removing these outliers (beta=0.13, P = 0.049, Supplementary Table 3 ).
In the skull EEG, there was an insignificant decrease in ITC at 40 Hz (t (10) =2.108, P =.061) and a nominally significant increase in ITC at 20-Hz stimulation (t (10) =2.237, P =.049).
The comparison of allele frequencies between the responder and nonresponder groups revealed a nominally significant difference for the rs235770 polymorphism ( p = 0.049).
Only the Body and Scar domain in the 8–17 year child self-report showed a nominally significant difference (0.72 vs. 0.42, p = 0.049, Cohen's d = 0.56), but this did not survive Bonferroni correction for five simultaneous comparisons (adjusted threshold p < 0.01).
However, this difference was only nominally significant (p = 0.049).
Interaction analysis indicated a nominally significant interaction between αT/(TCH+TG) and sex in relation to TgAb levels ( p = 0.049).
MSH3 expression was not significantly associated with somatic expansion ( P = 0.625), whereas the association of DHFR expression, while nominally significant ( P = 0.049), did not survive correction for the number of phenotypes tested.
Unadjusted means favored both support groups (control: 5.79; call: 6.57; SMS: 6.80); the prespecified SMS-vs-control contrast was nominally significant ( P =.049, small effect).
Results A nominally significant association with breast cancer risk was observed for MTHFR C677T polymorphism heterozygous genotype in the codominant model (OR: 0.57, 95% CI: 0.32–1.00, p = 0.049) and for Cys/Cys genotype of the OGG1 Ser326Cys polymorphism in the recessive model (OR: 0.23, 95% CI: 0.05–1.11, p = 0.0465).
Among 21 candidate variants including genes in the interferon response pathway, APOE , TMPRSS2 , TLR3 , the HLA complex and the ABO blood group, only rs1205, a 3’ untranslated region variant in the CRP gene, showed nominally significant association in T-dominant model analyses (odds ratio 1.859, 95%CI 1.001–3.453, p = 0.049) after adjustment for age, sex, center, body mass index, and a history of cardiovascular disease.
1 C); with a nominally significant increase in the non-delirious group (median increase of 11.4%, 95% CI: 0.0%–23.5%, p = 0.0491).
There was a nominally significant association between the s allele of the 5-HTTLPR polymorphism and TEM (odds ratio, 1.434; 95% confidence interval, 1.001–2.055; P = 0.0493; I 2 = 52%).
In uncorrected pairwise comparisons, only the proportion of activated NK cells showed a nominally significant difference between the IDD and control groups (raw P = 0.04949).
Additionally, there was a nonsignificant trend towards multiple repeat mutations (p = 0.5127), as well as, a nominally significant trend towards deletion mutations (p = 0.0495) (Table 6 ).
A nominally significant association with BPD was found for rs1006737 in CACNA1C ( P =0.0498).
Finally, we found significant differences in the frequencies of TAGA ( P = 0.005, OR = 3.187, 95% CI 1.376–7.382) containing rs4570625-rs11178997-rs1386494-rs7305115 between ODD and control groups (Tables 7 , 8 ). However, the further analysis by Haploview revealed the nominally significant finding for rs1386494 ( χ 2 = 3.846, P = 0.0499), and only one haplotypes (TAGA, χ 2 = 4.366, P = 0.0367) remained significant.
As most results were nominally significant (P < 0.05) but did not meet the stringent corrected threshold (P < 0.005), they are cautiously interpreted as indicating potential trends in the discussion of our findings.
There was a nominally significant three-way interaction term ( p = 0.05).