“of borderline significance”

Both manual parental social class and overcrowding in the household at birth were significantly related to reporting a cancer before 50 y, and mother’s education was of borderline significance.

After adjusting for multiple testing, both loci were of borderline significance (p adj = 0.054 and 0.031).

Thrombocytopenia at diagnosis (<50,000 platelets/microliter) was almost associated with higher hospital mortality (OR = 3.37 [0.99–11.39], P = 0.05 which is of borderline significance).

Birth outcomes by trial arm The mean birthweight was 100 g lower in the iron group (95% CI 205:5), P adj = 0.033), with a greater risk of LBW (OR: 1.34 (0.99–1.81) of borderline significance (P = − 0.062) (Table 2 ).

14 , 36 In addition to the differences in use of bleeding avoidance strategies, we saw a numerical decline in the bleeding event rate of borderline significance.

Once the age of the child is controlled for, then the relationship between HPV type and clinical course becomes of borderline significance. 35 None of the patients in our cohort were vaccinated at the time of the study.

The variations were of borderline significance and based on small numbers of cases (21 expected cases in January).

The magnitudes of these associations decreased by 30–47 %, and the association of leg muscle strength became of borderline significance after further adjustment for total tibial bone area (Table 4 ).

The association with BMI was of borderline significance, with obese individuals tending to have lower MeDi adherence.

However, these associations were only of borderline significance, and so need to be interpreted with some caution.

The results were of borderline significance in favour of fluoroquinolones for microbiological failure (0.43 (0.18 to 1.03), n=378, six trials).

MitraClip Iron deficiency Anaemia Functional outcomes At baseline, PCS , MCS, MLWHFQ, and NYHA class were similar by ID status, whereas 6MWD was lower in patients with ID, which was of borderline significance ( Figure 2 A – E ).

However, in the present study the enrichment of miR-93 in exosomes from BC patients was only of borderline significance.

4.7 Publication bias There was evidence of borderline significance for small study effect (p value 0.08, see Fig. 7 ). 5 Discussion Combining an iodinated contrast agent with FFDM (utilising a dual energy exposure undertaken during a single breast compression), CESM may improve diagnostic accuracy in the diagnosis and staging of primary breast cancer, particularly in women with dense breasts, due to its ability to identify breast cancer that might ordinarily be masked by the dense parenchymal background (DPB) patterns on a FFDM [ 13 , 19 , 20 , 27 , 41 , 42 ].

1 a, the increase in LBM from baseline was significantly greater in the 100-mg anamorelin group at weeks 8 and 12 than in the placebo group, although the LS mean change from baseline to week 12 was of borderline significance.

Furthermore, we observed a strong positive enrichment trend for pathways related to DNA synthesis and metabolism, including “Regulation of DNA Replication” (NES = 2.64), “Glycine, Serine and Threonine Metabolism” (NES = 2.64), and “Carbon Metabolism” (NES = 2.92), although the adjusted P -values for these pathways were of borderline significance (Fig. 7 G–I).

TIL levels significantly increased from baseline to matched RD in the overall population and in both A-TCb and AT treatment groups (with an association of borderline significance in the AT cohort), as shown in Fig. 4a .

In men, no variable was significantly associated with ukMI although the odds ratio (OR) for hypercholesterolemia was of borderline significance, 3.2 (95% confidence interval (CI) 0.9 to 11).

Meanwhile, genetic associations with a 5 × 10 −8 < p -value < 0.05 were defined as being of borderline significance in GWAS or meta-analyses of GWAS.

The only significant difference in any group was seen for non-BRCA mutation carriers, where I1307K carriers were significantly more likely to be grade 2 rather than grade 1 (OR 5.0, 95% CI 1.23-21, P = 0.04) but this was only of borderline significance.

reported a higher standardized mortality ratio for hypertension and cerebrovascular disease of borderline significance but no significant excess mortality from cerebrovascular disease in their geographical study [ 28 ].

Moreover, we found that expression of most of the differentially expressed genes (particularly those that were significantly different or of borderline significance) has been linked to TBI pathology ( Table 1 ).

Stratification by smoking status revealed a higher risk of CDW among current smokers with at least six amalgam fillings (HR 1.89, 95% CI 1.09–3.27), while the association was weaker and of borderline significance among nonsmokers (HR 1.28, 95% CI 1.00–1.66) ( Supplementary Table 6 ).

A sensitivity analysis of annual LVEDD change (mm/year <1 mm) also demonstrated the relationship between decreasing LVEDD and increased mortality in all subgroups, although the effect was of borderline significance in men ( Table 6 ).

In the present study, khat users were more likely to be ANA positive than nonusers, however, numbers were small and the increased proportion of ANA positive khat users compared to nonusers was of borderline significance, and hence the observed association is at best dubious.