“of borderline significance”

In multivariable analyses, a lower risk of death remained following adjustment for socioeconomic factors and comorbidity, albeit of borderline significance in men.

Identification of intermediate-risk patients based on RVD and/or laboratory biomarkers was performed in three studies 10 , 13 , 19 with a trend towards reduced mortality of borderline significance.

The review by Free et al [ 24 ] which achieved the highest AMSTAR score (9) found that mobile technology-based interventions improve glycemic control, but the effects were small and of borderline significance (MD -0.27% (95% CI:-0.48, -0.06), 5 trials, I 2 = 8.5%).

Previous TBI hospitalisation was significantly associated with all causes of SEN except for learning difficulty, autism spectrum disorder, and mental health problems, and the association with SEN attributable to communication problems was of borderline significance.

The SIR for concordant rectal cancer in offspring and parents was 1.77 and that among siblings was 1.96, of borderline significance.

Mixed multilevel multivariate logistic regression showed that relative to non-use, covert use was associated with higher odds of having at least 2 births [AOR (95%CI): 1.78 (1.11–2.86), 2.56 (1.43–4.57) for women with 2–4 and ≥4 births respectively]; and being Catholic versus Protestant [1.55 (0.99–2.42)], though the latter was only of borderline significance.

Although of borderline significance, we also observed a survival benefit with ever use of oestrogen-containing HRT.

Five SNPs were significantly associated with adverse events; three in the DHFR gene (rs12517451, rs10072026, and rs1643657) and two of borderline significance in the FPGS gene.

After adjustment for income, ethnicity, and pest-control mea- sures (Model I), degree of housing deterio- ration was of borderline significance Environmental Justice * Housing and cockroach allergens Environmental Health Perspectives * VOLUME 110 | SUPPLEMENT 2 | April 2002 325 Table 1.

Exposure to whole-body vibration was of borderline significance at L5-S1 (OR 1.05; 95% CI 0.99–1.12).

LVH, Biomarkers, and All‐Cause Death Compared with no/mild LVH with a KM‐estimated 5‐year mortality of 58.1%, moderate/severe LVH with a KM‐estimated 5‐year mortality of 69.6% was associated with increased mortality risk, although this was of borderline significance (Figure 3A ).

Vigorous physical activity showed a weak but deleterious association with medial tibiofemoral BMLs (PR: 1.02, 95 % CI: 1.01, 1.03) and the association with any knee BMLs was of borderline significance.

Several small differences in performance of the treatments were only of borderline significance as the study was underpowered.

Expiry at date of analysis was of borderline significance.

After adjustment for deprivation, however, the estimate of trend in 5-year survival was an increase of 3.3% every 5 years between 1986–1990 and 1996–1999, a trend of borderline significance (95% confidence interval 0.0–6.7%).

This was not entirely unprecedented; a large clinical trial comparing IB with placebo in mild COPD noted increased cardiovascular morbidity and mortality of borderline significance in the group assigned IB, and a particularly suggestive increase in the incidence of SVT ( Anthonisen et al 2002 ).

For participants with the wild-type G allele at the tagging SNP rs2761016, we observed an increase in RCC risk among participants exposed to lead ( GG genotype: OR = 2.68, 95%CI = 1.17–6.12; GA genotype: OR = 1.79, 95%CI = 1.06–3.04; AA genotype OR = 0.82, 95%CI = 0.29–2.35) with an interaction of borderline significance (p-value for interaction = 0.06).

Of note, the proportion of rejection was high in the single-centre study; however, a large proportion of the rejection episodes represented rejections of borderline significance.

When these three groups were analysed together, the difference was of borderline significance (RR 1.4, 95% CI 1.0–1.8).

Notably, we found a direct association of MD adherence with apoA-1 concentration, but this was of borderline significance after Bonferroni correction for multiple comparisons, though it could be of potential clinical significance.

Prandial insulin was also associated with a greater weight increase of borderline significance.

In our study, the knowledge that the Lombardy region offers HPV vaccination to 12 years-old adolescents for free positively influences parents’ willingness to have their sons vaccinated, but the OR is of borderline significance.

In the subgroup of geographic area, a decreased risk of borderline significance was observed for oral contraceptive users in European studies (RR=0.79, 95% CI=0.62–1.01), but this association did not emerge in the North American studies group (RR=0.99, 95% CI=0.81–1.21).

In the testing set, Snail (OR, 4.286; 95% CI, 1.692–10.858; P =0.002) and SVM model (OR, 9.231; 95% CI, 3.588–23.751; P <0.0001) showed significantly high power in predicting RLNM status; whereas age (OR, 1.970; 95% CI, 0.895–4.334; P =0.092) and nuclear β -catenin (OR, 2.981; 95% CI, 0.847–10.486; P =0.089) were of borderline significance.

The sentence has been amended by pointing out that numbers are small and the aOR from the sensitivity analysis have been added so that the readers can see the association for hypertension is of borderline significance: Line 222-223: “In the sensitivity analysis, there was some evidence that asthma and hypertension specifically increased the risk of admission, although the numbers in some groups were small (aOR 2.12, 95% CI 1.25-3.58 and aOR 3.63, 95% CI 0.99 – 13.30 respectively, Table S3).” line 255 when noting symptomatic SARS and pregnancy loss less than 24 weeks , if the authors do not wish to add the historical comparison can they explain why that is not used.