“reached borderline significance”

This reached borderline significance from age 75 onwards, with heterozygotes displaying a 32% lower risk of incident AD dementia compared to homozygotes for the major allele (HR = 0.68, 95% CI [0.47, 1.00], p = 0.049, n = 551, incident cases = 35).

In addition, 10 μ g sunitinib + 2 Gy IR was significantly more effective then sunitinib alone and reached borderline significance with 2 Gy IR (Fig. 6C ).

After adjustment for multiple testing, the difference was statistically significant on Earth but only reached borderline significance in space, Table 2 .

In our fully adjusted model, the effect of spring and summer temperature on mortality reached borderline significance, although in opposing directions.

However, the discrimination of IDI for prognostic value at 3 years only reached borderline significance.

Similarly, on the basis of the comments and after further discussion of the working group on results that reached borderline significance based on predefined thresholds, the domains were expanded with variables, such as new symptoms, for 45 items ( appendix pp 38–42 ).

Global budgeting did not significantly impact overall utilization of reconstructive procedures amongst Medicaid beneficiaries, though there was an increase in utilization of emergent/urgent reconstructive procedures that reached borderline significance (0.03% per quarter; 95% CI, 0.0%–0.05%).

The patients were inconsecutive and the sample size was small; therefore, some of the values only reached borderline significance.

Although all large HFpEF trials addressing renin-angiotensin-aldosterone system (RAAS) inhibitors failed to reach statistical significance for the primary outcome, many of them reached borderline significance for a primary endpoint or statistical significance for secondary endpoints, subgroups or post-hoc analyses [ 3 – 5 , 7 , 45 , 46 ].

Given that this finding reached borderline significance in the multivariable model, and that there was no prior belief that ceramic-on-polyethylene revision bearings would be associated with a higher re-revision risk, we cannot exclude a type I error.

In accordance, PAI-1, which increases coagulation system activation, was significantly higher in the evening measurements in the shift workers as compared with day workers and reached borderline significance in the morning measurement.

Restricted cubic spline analysis demonstrated a nonlinear relationship between serum 25(OH)D and risk of all-cause dementia ( P nonlinearity < 0.001) and VD ( P nonlinearity = 0.007), and the nonlinear association reached borderline significance for AD ( P nonlinearity = 0.06), with a threshold at around a serum 25(OH)D value of 50 nmol/L for all the outcomes.

5 The Shariff score was tested in a retrospective large cohort of patients with a median follow-up of 48 months: a score >3 at first implantation was an independent predictor of CIED infection while a score = 3 reached borderline significance. 6 Systemic antibiotic prophylaxis is recommended by international consensus and represents the standard of care. 7 The recommendations from the major heart rhythm societies clearly indicate to administer antibiotics 1 h prior to skin incision and suggest to prefer drugs that coverage Staphylococcus aureus species such as beta-lactams and glycopeptides. 7 Post-operative antibiotics administration has weak evidence, and its administration varies according to centre and operator practice.

It was significant in the discovery phase, reached borderline significance in replication and was significant in the meta-analysis.

AURKA reached borderline significance (P 0.073) in a similar analysis.

However, separated analysis of HR-positive and HR-negative cells after incubation with angiotensin II only reached borderline significance ( Fig. 3 ).

In addition, other female genital cancer reached borderline significance (95%CI 0.98–1.96).

Only the measured exercise capacity was proven as a significant predictor of survival in this cohort treated with palliative intent, whereas the self-reported exercise behaviour just reached borderline significance [ 30 ].

This BMI-methylation interaction reached borderline significance in formal tests for effect modification (p for interaction = 0.085).

At multivariate analysis (adjusting for the individual factors considered in the model reported in Table 1 ), history of blue-collar work reached borderline significance as a predictor of surgically treated CTS (OR, 4.2; 95% CI, 1.0-17.5).

Remarkably, the meta-analysis showed that the association between IL-10 and NAFLD reached borderline significance.