“showed a trend”

CT) showed a trend toward significance ( p = 0.0544), indicating a potential difference in the pain severity for individuals with the CT genotype compared to those with CC or TT genotypes ( Figure 3 C).

Cohort t -test evaluation showed that RT increased mean ADC significantly in three models (U87 p = 0.0121; HCT116 p = 0.0002; CT26 p = 0.0006) but only showed a trend with Calu6 ( p = 0.0545) and 4T1 ( p = 0.1003).

A multivariate regression analysis with MAO-B area fraction as outcome variable, Aβ+ area fraction, number of pTau+ neurofibrillary tangles, GFAP+ reactive astrocytes, and CD68+ reactive microglia, and cortical thickness as independent variables, and adjusted by age at death, confirmed that MAO-B expression level is independently associated with cortical thickness and number of CD68+ reactive microglia and showed a trend ( p = 0.0546) toward a positive independent association with the number of GFAP+ reactive astrocytes, but no significant association with either total Aβ plaque burden or the number of neurofibrillary tangles (Table 6 ).

In the multivariate analysis, concurrent RT emerged as the only independent factor (adjusted HR = 0.180, 95% CI: 0.051-0.632; P = .0075), while prior locoregional therapy showed a trend toward longer OS (adjusted HR = 0.351 95% CI: 0.121-1.021; P = .0546; Table 3 ).

After mice were exposed to SPS, the level of serum CORT showed a trend toward decrease in the Npffr2 -shRNA-treated group compared to controls ( p = 0.0547, unpaired Student’s t -test) ( Figure 6 B).

Out of the remaining four miRNAs, three miRNAs, miR-423-3p, miR-320a, and miR-99a-5p were significantly differentially expressed between treatment-naive PCa patients and CRPC ( p = 7.3 × 10 −8 , 0.002 and 0.0186, respectively) ( Figure 2A ), while miR-193a-5p showed a trend without a statistically significant difference ( p = 0.0547).

As for OW/MS+ individuals, red meat showed a trend toward a positive relationship (β = 16.16, p = 0.0548), and a negative association was observed with eggs (β = −310.14, p = 0.0272).

Although individual PD-L1 ligand expression status did not significantly influence disease-free survival (DFS) in GBM (data not shown), GBM patients with high PD-L2 expression showed a trend of shorter DFS than patients with low expression (Fig. 5A , left)(log rank test P = 0.0548).

In accordance with previous studies, 5 – 7 CEBPA -dm patients, compared to CEBPA -wt patients, showed a trend toward a higher complete remission rate after the first cycle of treatment (87.5% versus 61.0%, respectively; P =0.0549), longer overall survival (median not reached versus 22.3 months, respectively; P =0.00626; Figure 1A ) and longer disease-free survival (median not reached versus 26.8 months, respectively; P =0.0667; Figure 1B ).

However, in the multi-mutant LRRK2 6xD, kinase activity showed a trend to decrease ( p = 0.0549) ( Figure 4 A).

This effect showed a trend towards being better explained by the cubic function, with z = − 1.922, and p = 0.055, whereas the quadratic function did not yield a comparable decrease in error, z = 0.035, p = 0.972.

Compared with upfront surgery, neoadjuvant therapy showed a trend towards prolonged PFS in matched groups (p=0.055), but not in OS (p=0.81).

SNPs rs10507172 and rs10507173 were associated with IL-2 production ( p = 0.002) while two other SNPs (rs1305392 and rs1920413) showed a trend towards association with IL-2 production ( p = 0.055 and 0.080, respectively) (general linearized model, Fig 2A, 2C, 2E and 2G ).

There was no significant difference as regards gender, ethnicity, age and baseline immune-virological status between the two groups although females showed a trend towards a higher frequency of NVP-induced hepatotoxicity (75.0% vs 35.9%; p = 0.055).

3.02 months; p = 0.0064) and showed a trend toward better OS (p = 0.055).

Although not statistically significant, the TMB-high group showed a trend toward a higher frequency of intrahepatic tumor recurrence (52.6% vs. 27.1%, p = 0.055).

In the multivariate analysis adjusted for clinical variables associated with bleeding risks in the univariate analysis, the SIC score was independently associated with an increased risk of major transfusion (adjusted OR 1.535; 95% CI 1.153–2.045; p = 0.003), whereas serum albumin showed a trend toward a protective effect (adjusted OR 0.524; 95% CI 0.270–1.014; p = 0.055).

In subgroup analyses, in ER + /PR + /HER2 − , lower UNC5A H score showed a trend of poor overall survival ( p = 0.055) (Fig. 2c ).

Leptin levels significantly decreased in the LA group ( p = 0.046), and they also showed a trend in the HA group ( p = 0.055).

The average daily caloric intake also showed a trend to be higher (P = 0.055) in Vgat-Cre; Clk2 loxP/loxP males (13.61 ± 0.602 kcal/d, n = 6) than in control males (12.17 ± 0.394 kcal/d, n = 9).

Positive expression of p65 protein showed a trend of correlation with patient age (p = 0.055), but not with other clinicopathologic factors, including sex, disease stage, LDH level, B symptom, and MYC and BCL-2 expression levels.

Mean CAV-free survival was 47.5 months (95% CI [43.1–51.8]) ( Figure 1 ). Although the sample was substantively smaller and the follow-up time substantively shorter in the group that did not receive statin therapy ( Table 1 ), treatment with a statin after transplantation showed a trend towards improved CAV-free survival compared with those who did not receive statin therapy (p=0.055).

Compared to the B6 mouse, the SPRET mouse showed a trend towards higher levels of total cholesterol (TC) ( Fig. 1 Aa, P = 0.055), carried significantly higher levels of HDL-C (Fig. 1Ab, P = 0.012) ( Fig. 1 A), but similar levels of LDL-C ( Fig. 1 B, P = 0.295), leading to significantly lower LDL-C/HDL-C ratio ( Fig. 1 C, P < 0.001).

However, the TKD group showed a trend of reduction in sway velocity, particularly during double leg stance under unstable surface with eyes closed condition ( P =0.055; ES=0.8).

Correlation between clinical variables and GMV in patients with SCI and between clinical variables and GMV of SCI sub-groups In all patients with SCI, partial correlation analyses showed a trend toward negative correlation between right OFC GMV and the injury duration ( r = −0.448, p = 0.055, uncorrected).