“showed a trend”

By contrast, prior colic surgery showed a trend towards improved survival and fewer complications, but this apparently counterintuitive direction should be interpreted cautiously because it may reflect case selection and management factors rather than a true protective effect (for example, a healthy survivor effect, closer veterinary follow-up, or earlier escalation to definitive management).

The PEGR score showed a trend toward a reduction (improvement) from the first injection baseline in patient-assessed blepharospasm symptoms throughout the study period ( Table S5 ).

A high calcium diet habit showed a trend towards lower consumption in the HIV group.

Multiple stones (≥ 3 stones) showed a trend toward a higher symptomatic rate but did not reach statistical significance (85.7% vs. 71.4%, p = 0.089).

As shown in Table 3 , participants with high non‐ APOE PRS (above the second tertile) showed a trend toward benefit from statins use (aRD: −5.9‰, 95% CI: −8.1‰ to 1.2‰), while those with low non‐ APOE PRS showed no benefit (aRD: 0.8‰, 95% CI: −1.5‰ to 3.8‰).

1 A, on the one hand, as the soaking temperature gradually increased, the germination rate showed a trend of rapid rise at first and then a slow decline.

Importantly, albumin levels showed a trend increase, although without statistical significance, consistent with the fact that our included populations primarily consisted of non-cirrhotic MASLD patients, in whom hepatic synthetic function is typically preserved ( 29 , 30 ).

Larger PFO diameter (≥ 2.5 mm) showed a trend toward lower LA volume indices and E/e′, although differences were not statistically significant.

Expression of hypothalamic rx3 was low at this developmental stage, and showed a trend towards a reduction in star:bPAC+ compared with wild type (Fig. 4a, c ).

Social interactions with family and friends (AOR = 1.80, 95% CI: 0.94–3.45, p = 0.08) also showed a trend toward increased likelihood, though not statistically significant.

Its power generation output increased monotonically with a relatively slow growth rate, while the power generation efficiency showed a trend of rising first and then falling.

In this transition cohort, TaTME and R-TME achieved comparable short-term oncologic and survival outcomes; R-TME offered perioperative advantages, while TaTME showed a trend toward a longer distal margin that warrants cautious interpretation.

H2a showed a trend of increased interaction with OS-9 in the presence of ARF1[T31N], although the effect was not statistically significant.

Renal function, assessed by eGFR, showed a trend toward improvement, which is encouraging in a population at increased risk for chronic kidney disease due to metabolic comorbidities.

Knowledge of HBV infection showed a trend toward increased uptake, but the association was not statistically significant (adjusted OR = 1.38, 95% CI: 0.96–2.00).

In contrast, the expression of MYC_3 showed a trend of first increasing and then decreasing (Figure 4g ).

As the promoter fragment was progressively truncated, the LUC/REN ratio showed a trend of increasing–decreasing–increasing, indicating the presence of suppressor elements during the −665 bp to −1422 bp region (Figure S8C ).

Indeed, when the analysis was adjusted for MSA phenotype values only showed a trend, not statistically significant.

In these zebrafish, tardbp A379T/− showed a trend in lower Tdp‐43 expression levels and expression was significantly reduced in tardbp G347C/− with concomitant increased expression of Tdp‐43‐like V1.

As for the intermediate of 6H-DBT, its concentration showed a trend of first increasing and then decreasing with the advancement of the reaction time in different reaction temperature ranges.

Equivalent results were observed with lomitapide treatment in the Pan-European Lomitapide Study [ 24 ], which also showed a trend toward a greater reduction in LDL-C in HoFH female compared with males after 6 months of lomitapide treatment.

The intensity of these absorption peaks showed a trend of first decreasing and then increasing before glycine leaching, after leaching, and after CO 2 mineralization.

Two randomized Phase II trials in non–small cell lung cancer [ 18 , 19 ] demonstrated that RT administered before or concurrently with anti–PD‐1 antibody prolonged PFS and showed a trend toward improved OS compared with ICI alone, with pooled analyses reporting a hazard ratio of 0.67 for both PFS and OS [ 20 ].

Neither FIGO stage at diagnosis nor number of received NACT cycles appeared to affect perioperative outcomes, even if women submitted to > 4 cycles of NACT showed a trend toward a more deranged postoperative creatinine serum level and longer median hospital stay, which can be explained by (i) the higher rate of small/large bowel resection perfomed in this popualtion, (ii) by the cumulative toxicity from chemotherapy, and/or (iii) by the usual higher rate of comorbid

Egr3 also showed a trend of upregulation with a log 2 (fold change) value of ∼1, but it was insignificant due to low expression and high variability.