In patients with RMS, an incomplete B-cell depletion or higher B-cell counts in blood before the next infusion showed a trend toward elevated risk of disease progression [ 77 ].
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Similar observations have been made across products and indications: in patients treated with tisagenlecleucel, for example, CD19-dim B-ALL cases showed a trend toward a higher rate of failure to achieve deep remission (Pillai et al, 2019 ).
Total parathyroidectomy showed a trend toward fewer failures than subtotal parathyroidectomy.
INR (OR 5.23; 95% CI: 0.99, 27.62; p = 0.051) and hsTrop-I (OR 1.49; 95% CI: 0.99, 2.24; p = 0.053) also showed a trend towards predicting 30-day mortality.
Kellgren–Lawrence grade showed a trend toward higher odds of lympho-myeloid infiltration (OR 1.54, 95% CI 0.96–2.51) but did not reach statistical significance ( p = 0.074).
AF Classification: In the paroxysmal AF subgroup, the combined approach showed a trend toward higher procedural success (OR 0.75, 95% CI 0.36–1.57) and lower event-free survival (OR 0.60, 95% CI 0.34–1.05).
Notably, the trial showed a trend for greater benefit with an increasing number of previous miscarriages, generating the hypothesis that a subgroup effect existed with a biological gradient related to the increasing number of previous miscarriages. 20 2.2.
Behavioral testing at 2 months revealed that Kir2.1-expressing mice (injection of AAVs with Kir2.1 at P7) showed a trend toward decreased distance traveled and percentage time spent in center ( Figure 7L–N ).
Conclusion Compared with wideband PSIR, wideband SPOT showed a trend towards enhanced scar detection, identifying additional scarred segments while maintaining similar overall scar burden.
Alpha diversity for each individual sample, calculated using Chao1 index at genus level, showed a trend toward higher richness in black samples, although this difference was not statistically significant (Wilcoxon t ‐test, p = 0.4; Figure 3I,J ).
Atezolizumab combined with Entinostat and chemotherapy (Atezo-Entino-chemo) showed a trend toward improved OS (HR = 0.49, 95% CI: 0.22-1.12) and ORR (OR = 5.14, 95% CI: 0.70-37.94).
In the VKA/LMWH group without prior VKA treatment, protein C showed a trend toward decrease from baseline at week 2 and a statistically significant decrease at month 6 ( P =0.004).
Compared with alirocumab, statins showed a trend toward reduced risk of the primary composite outcome, which included cardiovascular death, MI, HF, stroke, and coronary revascularization.
Gene Set Enrichment Analysis (GSEA) of TCGA-EAC database, comparing PRDX2-high and PRDX2-low groups, showed a trend for enrichment of the deubiquitination pathway in the PRDX2-high group, despite a non-significant p-value.
In this sense, patients with hypocomplementemia showed a trend towards a lower number of pregnancies, as well as a higher frequency of early abortions and PE.
Regarding clinical outcomes, the ESPB group showed a trend towards shorter hospital length of stay.
Relative to control cells, exposure to CTK-2 showed a trend toward reduced complexity in the peak/early-decay region but did not reach significance in this dataset when tested per radius ( Figures 6E,F ).
Although not significant, the Ta/Tp MIS group also showed a trend toward fewer intraoperative complications than the non-Ta/Tp MIS group.
Repositioning times showed a trend towards improvement in first-to-best transfer attempts, median ∼35 s (sitting to supine) and ∼30 s (prone to supine).
Notably, the low dose of 5 mg/kg in mice gives an HED of approximately 0.4 mg/kg/day (24 mg/day for a 60 kg adult), which also showed a trend of alleviating intestinal injury and significantly prolonged the median survival time of irradiated mice.
Country of origin showed a trend toward an association with IGRA positivity, with non-Irish subjects demonstrating a higher prevalence of TB infection compared to Irish-born individuals (23.8% vs. 8.2%, Fisher’s exact test, p = .054).
Chemotherapy (CTx) only group Among patients treated with CTx alone, CS showed a trend toward inferior outcomes, though this did not reach statistical significance.
Conversely, ALA exhibits the lowest crystal purity under identical feed purity and recovery yield conditions. CIT showed a trend between those of HIS and ALA.
3.2.2 Accuracy In terms of accuracy, results showed a trend toward group differences.
However, baseline measures showed a trend toward the LIV, though somewhat weaker than for the derived network indices.