also reported significant differences in SUVs as a function of breast tissue density and showed a trend of negative correlation between age and SUVs with a decrease over time [ 37 ].
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In the literature
The small number of cases examined do not establish an evident correlation with Gleason grade or tumour extension (evaluated as n° and percentage of tumour involvement on at least 12 diagnostic biopsies), although showed a trend for increased percentage of CD44v8-10 positive tumours with higher Gleason grade group (Table 1 ).
Our study determined the utilization of an incremental number of imaging modalities ordered (echocardiography, cranial CT scan, and carotid ultrasound) and its impact on the hospital LOS which showed a trend towards a prolonged course although it was not statistically considerable.
At 6 months of age, male mice also had significant reductions in the maximum load force and bending stiffness, while the μCT data only showed a trend toward reduction in cortical bone mass.
The difference in movement accuracy between the physical abacus and hands-free spontaneous gesture conditions showed a trend in increased movement accuracy following skill level; beginning learners had low movement and gesture accuracy while intermediate and advanced learners had high accuracy.
Our results also showed a trend for prolonged median PFS (gefitinib group, 7.1 months vs. 4.9 months; erlotinib group, 7.7 months vs. 3.4 months) and OS (gefitinib group, 19.1 months vs. 14.0 months; erlotinib group, 15.5 months vs. 12.7 months) in patients with adenocarcinoma as compared with squamous-included NSCLC.
Enzymes involved in fatty acid beta-oxidation, including ACAA2 and HADHA, also showed a trend of lower abundance in the livers from older individuals (Additional file 10 : Figure S3A).
However, within the UK the rate of hospitalisations prior to IOS compared to the IOS observation period showed a trend to improvement but this did not reach statistical significance (p = 0.098).
Furthermore, we assigned a one-star recommendation to formulations that showed a trend supported by two or more studies, including Saccharomyces boulardii (minimal daily dose: 10 billion CFU) [ 65 , 66 , 68 , 70 , 75 ] and Bifidobacterium bifidum , Bifidobacterium lactis , Enterococcus faecium , Lactobacillus acidophilus , Lactobacillus paracasei , Lactobacillus plantarum , Lactobacillus rhamnosus , Lactobacillus salivarium (minimal daily dose: 10 billion CFU) [ 63 , 64 ].
In a multicenter study, self-aggression in migraine patients compared to healthy controls showed a trend towards higher scores due to a small sample size [ 30 ].
The CD spectra of Luc–B 4 C mixture with 10:1 and 1:1 ratio showed remarkably lower ellipticity values as compared with untreated Luc, and the corresponding secondary structure distribution showed a trend similar to that of Luc–Cu mixture.
The incidence of CSs showed a trend towards an increase with stimulus intensity but became saturated or decreased at higher intensity.
In the present study, we found that riluzole treatment showed a trend towards reduction in human APP mRNA levels and a significant decrease in APP protein levels in 5XFAD mice.
GmIPT3 is expressed at levels twice that of both GmIPT15 and GmIPT4 , which showed a trend of upregulation in the rhizobia inoculated roots.
This is also reflected in the VAS scores of patients' satisfaction that showed a trend towards improvement.
In addition, the dose of 50 mg/kg also showed a trend in the inability to stay on the rotarod in females.
Second, the only body segment that showed a trend for positive parameter estimator rather than negative (though not significant above baseline) in response to unilateral stimulation was the shoulder and upper trunk.
Although MES results showed a trend of attenuating seizure intensity in mice but none of the tested compounds at the dose of 40mg/kg produced significant protection against seizure compared with the control group.
However, piglets supplemented with FOS did not significantly differ from the control group at either time point, but only showed a trend for a difference on day 14.
However, the polynomial regression model showed a trend for an increasing probability for surgery to fail with increasing of age.
All outcome measures showed a trend towards poorer quality of life with greater doses of OCS, except for the comparison between those on no prednisolone versus those prescribed 1–9 mg·day −1 .
On the other hand, although only two channels with significant correlation coefficients (i.e., channel 12 and 16 for oxy-Hb) were identified for the social- & self-help score, we could observe that most channels in left hemisphere showed a trend of negative correlation (panels e and f of Fig. 4 ).
Results (as presented in Figure 2 ) showed a trend such that participants thought that their peers would describe the ideal man as less communal than they on average actually described themselves, paired samples t (63) = –1.98, p = 0.052, d = –0.25, yet this effect did not reach significance.
Studies that used 20 mg of citalopram or escitalopram for 7 days showed a trend towards higher accuracy than studies that administered a single dose of antidepressant.
Interestingly, the combination treatment of ALX148 and anti-PD-1 showed a trend towards reduced CD4 + Treg infiltrates and decreased proliferative potential as evidenced by reduced Ki67 staining ( Fig 8A and 8B ).