Those cHL patients possessing a high TAM content, identified using CD68 or CSF1R, showed a trend toward reduced progression free survival and a significantly shorter OS in this study.
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Neuroticism, living situation, disorganized and negative symptoms, and passive coping style all showed a trend for significance.
Although our TD infants demonstrated differential looking in the Configural condition (as expected), it is unclear why they showed a trend toward the familiarized face in the Featural condition and a significant bias toward the novel face in the Configural condition.
Analysis of the data showed no significant differences between agreement and intensity [ Figure 5 ], but showed a trend toward higher intensities being rejected by the pathologist (unsure category).
When looking closer at the single gene level, several genes encoding cyclin dependent kinase inhibitors showed a trend for overexpression in the high LC50/GI50 group and of these CDKN1A was more highly expressed in the high LC50/GI50 group than in the low LC50/GI50 group, suggesting that high basal expression of CDKN1A might protect cells from HDACi-mediated cytotoxicity.
The same analysis was repeated for the Meta-Clinical dataset and the differential expression of 6 of the 7 RTKs was validated (FDR < 0.05, Supplementary Table 3 ), except for EPHA2 , which however showed a trend of differential expression (FDR = 0.052).
This finding is consistent with that of an earlier study [ 22 ] that showed a trend of higher expenditure for younger children.
Importantly, LPS was significantly increased after 49 weeks of HF–HC–HFD although it showed a trend of increase even at the earlier time points (Figure 3 p).
Interestingly, although no evidence of lag-1-sparing following an emotional distractor emerged in the group analysis, roughly half of the participants showed a trend towards better performance at lag-1 than at lag-2.
While expression of Lhb and Cga showed a trend toward being reduced in Foxm1 null embryos, this was not statistically significant.
However, AKT1 or AKT2 increases correlated with, or showed a trend towards correlation with tumor size, suggesting their involvement in advanced stage.
Interestingly, patients with tumors showing more than 50% of p53-positive cells showed a trend of worse survival rate than those with tumors lacking or expressing p53 in <50% of neoplastic cells ( 4 ).
The exploratory analyses on the first pieces of information provided for each trial showed a trend-level effect of the addressee’s likely knowledge, with more descriptions and less characters’ names as first pieces of information for likely unknown movies.
Regarding histomorphometry (Table 4 ; Figures 6 and 7 ), there was no statistical significance among groups in any of the parameters measured, although the superficial fibrillation index (FI) showed a trend to approximate to the control group values.
Calcium; vitamin D; and multivitamin ingestion were significantly associated with the diagnosis ( p values < 0.0001; 0.014; and 0.045 respectively); while the presence of hypertension; diabetes; and renal insufficiency showed a trend towards statistical significance.
When EGFR expression was evaluated at the same time-points, it was shown that more patients harbored EGFR-positive CTCs on disease progression compared to the pre-treatment sample and this difference showed a trend for statistical significance.
This result was also reflected at the level of cytokines, where IPDPF showed a trend towards increasing the levels of some pro-inflammatory cytokines in DSS-treated animals.
CDK6, the kinase responsible for the activation of cyclin D, showed a trend similar to its cyclin in wounds treated with vehicle (Figures 3(b) and 3(c) ).
Accelerated NSCLC development in K-ras LA1/+ ; Msh2 − / − mice Tumor diameters, measured as an indicator of tumor growth and development, revealed that 90–120 days old K-ras LA1/+ ; Msh2 −/− mice showed a trend toward increased tumor size (although no statistical linear trend was observed), compared with K-ras LA1/+ mice, indicative of accelerated NSCLC growth (Fig. 1C ).
Similarly, IQ score was directly proportional to size of the left subcallosal, anterior cingulate and suborbital cluster (ROI F , β = 14.1, t = 3.27, p Bonferroni = 0.034) and also showed a trend towards association with the left temporal inferior gyrus (ROI E , β = 13.5, t = 2.79, p Bonferroni = 0.099) (see Fig 1 ).
Among patients treated with allogeneic stem cell transplantation those with SLLP1 expression showed a trend towards a reduced overall survival.
68 A clinical trial in otherwise healthy RSV-infected adults showed a trend towards reduced mean viral titres and clinical severity scores, although neither reached statistical significance. 69 ALN-RSV01 has also been tested in a small cohort of RSV-infected lung transplant recipients ( n = 24; ALN-RSV01 = 16, placebo = 8).
Lungs infected with the ADPRT-deficient strains PA99S(E379A/E381A)bla or PA99S(R146A/E379A/E381A)bla showed a trend towards smaller FOCI within the lungs (Fig 4B and 4C ), suggesting that FOCI development and expansion was delayed during infection caused by these strains.
However, PIK3CA mutation showed a trend toward a significant adverse effect on OS with a pooled HR of 1.83 (95% CI, 1.05-3.20) in NSCLC patients treated with EGFR-TKIs ( Figure 5C ).
When ifferentiated into the different sample areas, all the litter materials showed a trend to having the highest moisture values in the drinking areas.