In some European studies, colorectal cancer showed a trend of increasing incidence from 1984 to 2007 [ 27 , 28 ].
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[ 23 ] who compared the two methods and showed a trend towards higher values in the range between 0 and 20% DNA methylation.
The proliferation showed a trend to correlation with patch test score (Figure 1 B) although there was substantial variability in the proliferation observed in patients with high score, such that the correlation did not reach statistical significance with this number of patients.
However, unlike the results of our study, another study also indicated that colonic paracellular permeability was not significantly altered by DSS exposure, and DSS mice only showed a trend of increased expressions of claudin-1 and claudin-2[ 27 ].
Subjects experiencing baseline suicidal thoughts, assessed by MADRS item 10 score ⩾2, also showed a trend for a numerically superior response to lanicemine over placebo.
In addition, the rise of Ca 2+ influx caused by the aggregated peptides showed a trend and time dependency similar to that observed for the MTT reduction assay.
We analyzed the BE, ED and EA scorings of those five cases for which the entire pathology progression was available: hERG1 positive BE samples showed a trend to increase hERG1 expression during progression (Figure 1K and Supplementary Table S1 ).
Accordingly, we could show that short intercellular distances in the epithelial compartment showed a trend towards a favourable prognosis, whereas in the stromal compartment long distances predicted an improved prognosis.
Kaplan-Meier survival analysis showed a trend toward even shorter overall survival in the patient group with Barx2-negative tumors, independent of advanced UICC stage and tumor relapse.
Transformations of ZnO–NPs had been previously reported in other species including some desert plants [ 43 ], where seed treatment with ZnO–NPs (8 nm) did not affect germination but the seedling roots showed a trend of reduced length and to transform the NPs into Zn-nitrate, Zn-phosphate, and Zn-citrate.
( 12 ) involving 68 men who underwent nerve-sparing radical prostatectomy, 30 men who received PVS to the frenulum daily for 6 weeks, using the Ferticare ® vibrator, showed a trend towards better erections.
Additionally, FGFRL1 (cg25932599; r = −0.27; p = 0.059) and PIPK1A (cg06936779; r = −0.26; p = 0.067) showed a trend for statistical correlation with BMI.
A study of 118 autopsies of subjects age 20 to 100, demonstrated increasing proportions of GM3 with age[ 40 ], and two neuropathological studies showed a trend of higher GM3 in basal ganglia of PD brains compared to controls[ 41 , 42 ].
Other markers such as vascular endothelial growth factor ( VEGF ), catechol O-methyl transferase ( COMT ), and tissue factor ( TF, a coagulation factor) were not significantly different from control although showed a trend toward a decreased expression.
In HC, this relation showed a trend towards the opposite direction (i.e. a higher DMN connectivity was related to a lower connectivity in the sensorimotor network), although this effect was not significant.
The extent of exposure, as indicated by area under the drug plasma concentration–time curve from time zero to the time of the last quantifiable data point (AUC last ) and C max , was generally similar between the matched treatment groups (Table 5 ), with the exception of the gMean ratio of AUC last for subjects with severe renal impairment, which showed a trend towards a higher value compared with matched healthy subjects.
The temporal variation of the depth of the siphon showed a trend similar to that of the distance between the end points of the lobes.
Exploratory analyses conducted to assess the impact of dilmapimod on CRP showed a trend of lower levels of CRP present at later time points (e.g. 72 h post dose) at all dilmapimod dose levels, relative to placebo [ 10 ].
In our analysis, there was a trend for group differences for the variables Loudness recruitment for 1 and 4 kHz (loudness scaling) ( p < 0.05), as well as for the variables Medium loudness level for 1 and 4 kHz (loudness scaling) ( p < 0.05), such that HAU showed a trend for higher values.
WT mice also showed a trend for increased GluN2B expression in the BLA but this was also not statistically significant [ F (1, 675) = 3.41, p = 0.065].
At the same time, the level of COL19A1 in HDFs was gradually increasing with the extension of time treated by BoNTA at the dosage of 5 U/10 6 cells ( Figure 6 ), and its level showed a trend of increasing when the dosage of BoNTA ranges from 2.5 U/10 6 cells to 7.5 U/10 6 cells ( Figure 6 ). 4.
Likewise, these people had significant higher non-fasting glucose levels and showed a trend toward higher levels of HbA1c and fasting glucose ( Table 1 ).
For the continental soccer confederations of South America (CONMEBOL) and North-Central America (CONCACAF), results showed a trend toward an expected relative age distribution, but results were not significant, South America, χ 2 (3, n = 115) = 4.03, p = 0.26, North and Central America, χ 2 (3, n = 92) = 0.96, p = 0.81.
Survival analysis showed a trend for better OS in patients treated for primary advanced ovarian cancer than in those treated for recurrence, but significantly better PFS.
All six groups, except for the low BMI group that did not develop diabetes, showed a trend of decreasing HOMA-β over time.