Regarding the morbidity site, intestinal toxicity was present in 38% of the patients, while 46% of the 37 patients presented irritable bowel as comorbidity; although in the multivariate analysis, no statistical significance was observed between the association of the irritable bowel and chronic toxicity, it showed a trend.
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In contrast, the combined group showed a trend of reduced bone marrow suppression, which may be related to elemene's role in enhancing the immune function of the body.
Supplementation of BMP-2 through saline injections into the bone tunnel showed a trend towards reduced cross sectional area.
Similarly, sensory-evoked gamma power increased with pre-stimulus auditory cortical desynchronization and showed a trend to saturate at intermediate levels.
Patients treated with a shorter prosthesis-free interval showed a trend towards lower reinfection rate (6%) compared with patients with a longer one (14%).
In detail, at one-month post vitrectomy, VLD and VT significantly changed in parafoveal region ( p = 0.043; p = 0.045), while PD and VDI showed a trend of increase in both parafoveal and perifoveal region.
Also, male IBD patients showed a trend toward lower BMD [ 12 ].
In three remaining ROIs (the entorhinal cortex, the gray matter in the frontal lobe, and the caudate nucleus), the APTw values in the aMCI group showed a trend toward higher levels, but the increases were not statistically significant, compared to the normal control group ( P > 0.05).
The intervention also showed a trend towards reducing HIV or HSV-2 prevalence among males with a high-level exposure to the intervention.
HDAC10 −/− CD4 + CD25 − T cells showed a trend towards reduced Foxp3 + iTreg polarization upon CD3ε/CD28 mAb co-stimulation in the presence of TGF-β and IL-2 (Fig. 2C,D ).
Instead of rapid ATP depletion, these mice showed a trend toward normalization after P34 (Fig. 1f ).
Lasmiditan only showed a trend to decrease blood pressure at the highest (supratherapeutic dose), which, based on the affinity of lasmiditan (see Table 1 ), could be due to a non‐selective activation of prejunctional 5‐HT 1D receptors and subsequent inhibition of sympathetic perivascular nerves (Villalón et al., 1998 ).
Expression of MGMT was higher in CH2879 cells as compared to JJ012 and SW1353 cells and Spearman correlation analysis showed a trend towards an association between expression and temozolomide GR 50 values in these cell lines, although sample size was small ( Figure 4 D,F).
In pancreatic cancer, systemic levels of IL-1β and IL-6 showed a trend towards the development of future thrombosis [ 44 ].
With the extension of cold stress time, the transcript abundance of all CsC5 - MTase genes showed a trend of continuous decline and reached the lowest point of transcript abundance at 48 h.
In fact, the CABG group showed a trend of lower mortality and MACE after 5 years in our follow-up.
The MBC data ( Table 3 ) showed a trend similar to that of the MIC data ( Table 2 ).
DISCUSSION This study showed a trend of increasing colorectal cancer in Korea.
Removal of PLX3397 by 18DIV showed a trend that by 21DIV had recovered microglial Iba-1+ cells to 30% of control levels.
Another study in AUD showed a trend ( 27 ), while two studies in AUD ( 29 , 30 ), and one in binge drinkers ( 36 ) found no effects.
However, the aGH group only showed a trend toward lower p-Stat5 count, not statistically significant from control rats.
Secondary analyses of food intake in relation to gastrointestinal symptoms were underpowered but mostly trended in the anticipated direction; FODMAPs consumed at a meal showed a trend for a greater percentage of symptoms arising after the meal for participants with IBS-D, and fiber intake was correlated with symptom duration in participants with IBS-C.
The PEBBLES pilot study showed a trend towards reduced food sensitization with regular emollient therapy. 30 Larger and robust studies on skin barrier preservation and food allergy prevention are underway.
Quantification of CNS infiltrating CD4 + T cells ( Figure 6K ) showed a trend toward reduction of the numbers of CD4 + T cells in the brain of ICAM-1/-2 −/− mice suffering from either typical and atypical EAE.
Analysis of LFS and OS in t(8; 21) AML With a median follow-up of 12.7 (range 1–44) months, the inv(16) cohort showed a trend towards superior LFS versus the t(8; 21) cohort, but it did not reach statistical significance ( P = 0.066).