“showed a trend”

Although gene expression showed a trend toward concordance with copy-number changes in general, each single-cell DNA sequencing result showed greater concordance with bulk or other single-cell DNA results than with its own RNA sequencing pair when unsupervised hierarchical clustering was performed for CNVs ( Supplemental Fig.

This post hoc analysis showed a trend towards an increase in the average number of minutes on days of CPAP use with SensAwake in the initial four weeks on their first treatment with SensAwake ON ( n = 18) compared to SensAwake OFF ( n = 12), which did not reach statistical significance (SensAwake ON 322.89 ± 26.46 versus SensAwake OFF 282.25 ± 30.58).

Infants with an IL-10 high-producer allele showed a trend (albeit not significant) towards a lower prevalence of severe ROP [ 60 ].

When comparing between the normal group and each Ludwig stage, the frontal and the occipital areas showed a trend toward decreasing non-vellus hair diameter, but with no statistical significance.

Comparison of the phenotype of the Adamts5 -/- -J mice of the present study with that of the Adamts5 -/- -P mice reveals some similarities supporting specificity of the phenotype, but also some quantitative and qualitative differences: (i) with respect to WAT mass: in Adamts5 -/- -J mice lower sWAT and GON fat mass was found, which was significant after 2 weeks of cold exposure, but only showed a trend in the DIO model; (ii) with respect to BAT mass: in Adamts5 -/- -J mice no significant difference with WT mice was observed after 2 weeks of cold exposure nor in the DIO model; (iii) with respect to browning of WAT: in Adamts5 -/- -J mice higher expression of UCP-1 mRNA and protein was found after 2 weeks of cold exposure (mRNA: 1.5- to 2-fold as compared to 5-fold for Adamts5 -/- -P mice).

Adipocytes treated with IGFBP-2 for 24 h followed by 30 min stimulation with IGF-1 showed a trend increase in glucose uptake.

Moreover, the chronic treatment for 15 days with trolox showed a trend toward a reduction of oxidative stress induced from Aβ plaque and toward a reversal of the structural changes in dystrophic neurites associated with Aβ plaque [ 59 ].

In a study of therapeutic effects of ipilimumab (monoclonal antibody targeting CTLA-4), an increased secretion of IL-1β, IL-2, IL-4, IL-5, IL-7, IL-8, IL-10, IL-13, IL-17, Granulocyte-colony stimulating factor (G-CSF), Granulocyte-macrophage colony-stimulating factor (GM-CSF), HGF, IFNγ, Monocyte chemoattractant protein 1 (MCP-1, CCL2) and VEGF from peripheral blood mononuclear cells (PBMCs) showed a trend towards better recurrence free survival in melanoma [ 69 ].

2009-2012) showed a trend not related to VC (Fig. 3), especially in the province of Messina, where to a low VC corresponded a relevant increase in intussusception hospitalization rate.

Our results showed a trend similar to adults or adolescents, suggesting that vitamin D may play important roles in the development of MS even in earlier aged children.

Furthermore, Runx2, OPN and OCN expression was investigated by western blot analysis, and the results showed a trend similar to that observed by RT-qPCR (Figure 2B ).

Moreover, molecular nonresponder patients showed a trend towards increased frequency of Tregs compared to responder patients, but no changes were observed in terms of absolute numbers of Tregs.

One study showed a trend for whole blood to be more sensitive (85% versus 79%) and to yield an earlier positive result (36 days versus 15 days) than for serum [ 85 ].

Pretreatment with TRO40303 inhibited depolarization, although 3 μM showed a trend to be more effective than 1 μM TRO40303 .

This study showed a trend toward a protective effect of 5μM nBR in insulinoma cell line (INS-R3) cells exposed to hypoxic stress ( Fig. 6 ), but protective effects were less apparent than those seen in intact murine islets ( Figs. 8 and 9 ).

The results of the present meta‐analysis showed a trend toward a lower risk of all‐cause mortality for obese patients as compared with normal weight patients, but it did not attain statistical significance (HR 0.87, 95% CI: 0.75–1.01, P = 0.058, I 2 = 91.8%; Figure 2 a).

Analysis of the correlation between HbA1c level and blood glucose fluctuations in drug‐naïve Japanese patients with type 2 diabetes showed a trend towards larger swings in blood glucose levels with high HbA1c levels. 8 Diabetes patients seen in clinical practice represent a wide range of patients and include drug‐naïve patients.

Interestingly, post hoc analyses showed a trend toward longer survival with CA4P–CP–bevacizumab compared with CP–bevacizumab in patients with tumors >10 cm (median OS 14.2 vs 11.0 months; HR = 0.67 [95% CI, 0.26–1.70]).

However, in patients with T2DM, those treated with volixibat showed a trend towards increased levels of serum HDL-C, decreased levels of serum triglycerides and reductions in fasting glucose levels, suggesting improvements in both lipid and glucose homeostasis.

The treatment of water showed a trend towards a protective effect but this was not statistically significant (OR 0.31 (0.09–1.04), p = 0.06).

Another study showed a trend in favor of ST at five days after surgery (UC 3.1 ± 2.4 vs ST 1.6 2.6; P 0.0752) using urinary pads [ 11 ].

The protein expression of TLR5 was significantly increased in amnions with HCA ( p <0.05) and showed a trend toward an increase in chorions with HCA, whereas no significant difference was detected in the villi and decidua.

ILD showed a trend toward greater frequency in antisynthetase antibody-negative IMPP compared with DM-VP (26% and 10%, respectively), but the difference was not statistically significant.

Notably, the clinical whole-blood signature showed a trend toward decreased inferred abundance in monocytes and M2-polarized macrophages, and as expected, no strong representation of pneumocytes.

Our results showed a trend of longer time-to-antibiotic administration in handover group, however this was not clinically nor statistically significant.