Furthermore, a significant group effect and the interaction effect of group by time with a trend toward significance were detected in epinephrine levels: The KRG group showed a trend to decreasing epinephrine after treatment, whereas the placebo group showed increased epinephrine.
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Gene expression of Ddit4 showed a trend toward downregulation ( Figure S3 B).
Interestingly, HbA1c levels showed a trend toward increase in the control group, and this could be explained by the fact that pharmacological antidiabetic treatment is not adequate to maintain fluctuations in HbA 1c , and other aspects, including stress and sleep, should be considered. 37 , 38 In addition, previous case reports suggested that increasing HbA 1c despite antidiabetic medication could be due to hereditary persistence of hemoglobin F.
In comparison with the inconsistent glycemic effects observed in the rodent studies, a clinical weight loss study with chronic nasal OXT treatment showed a trend toward improvement of postprandial glucose and insulin [ 22 ].
Other genera such as Lactobacillus and Bifidobacterium also showed a trend in reduction, though without a statistic difference.
The two ratios that were known for this patient were higher than the cut-off values and, thus, showed a trend to be classified as an HNSCC-CP.
38 Two-month treatment with paroxetine showed a trend toward a higher percentage of patients without PAs (50%) than citalopram (24%), suggesting higher antipanic efficacy of paroxetine, possibly related to its adjunctive anticholinergic properties. 50 Considering that paroxetine showed direct effects on respiration in animal studies and capability of decreasing respiratory irregularity in Is-PD, 51 this compound may be particularly suitable for Is-PD with respiratory profile.
In addition, the DM group showed a trend toward a higher total in-hospital mortality rate than the non-DM group, although without statistical significance (30.6% vs. 23.1%, P = 0.112).
The analysis using a Scale of Magnitudes for Effect Statistics showed a trend toward a decrease in angiogenesis [0.58 (1.79/-0.63)] and injury [0.55 (1.76/-0.66)] and an increase in inflammation [0.67 (1.89/-0.55)] with threshold moderate effects.
However, when looking at individual studies, all studies, except the third smallest study of Godfrey et al, 14 showed a trend toward decreased mortality in the partially/noncompliant subgroup.
Studies looking at whether three doses (at week 0, week 4, and week 24) of vaccine could increase rates of seroconversion as compared to the two-dose schedule showed a trend toward higher rates of seroconversion (84.2% vs. 78.1%) but did not reach statistical significance [ 1 , 5 ].
Attending a continuous professional development (CPD) course on OC showed a trend with satisfactory clinical knowledge, although it was not statistically significant.
With the increase of driving duration, both indicators and their variances showed a trend of increasing continuously.
This analysis revealed a decrease in the phosphorylation levels of Mek1 and p90 RSK in iron-loaded livers, and only marginally in case of Stat3 ( p < 0.0571); similarly, the levels of pErk1/2 showed a trend towards a decrease however the data were under the level of statistical significance ( Figure 1 ).
In addition, in the case of women, the relationship between caregiving status of family members requiring ADL assistance and depressive symptoms showed a trend of increasing depressive symptoms in older age, and higher depression scores were obtained in the 65–74 years old group and the 75 years-or-older group ( β 0.226, P = 0.0010 and β 0.082, P < 0.0001, respectively).
This study showed a trend for leaf length difference that favors the cultivar Toe Jam Creek by 4.5 cm over the wildland population from Grass Valley.
This finding was robust to adjustment for psychological well-being constructs and also showed a trend with decreasing life purpose.
Based on RT-qPCR, our data showed a trend towards increased vegfaa expression at 1 dpci, although this was not statistically significant, unlike the concomitant changes in nrp1 .
Individuals in the fittest group showed a trend towards lower BMI and WC than those in the middle and unfit group.
As expected from previous studies ( 7 , 11 ), 4 h LPS stimulation upregulated the expression of Il-1 β, Il-6 , and iNos mRNA and iNos protein, whereas Dex treatment during LPS stimulation significantly reduced their expression, and Il-6 protein showed a trend in reduction ( Figures 1A–E ).
NY‐ESO‐1‐positive cases showed a trend towards a poorer outcome (Figure 3 B), but there was no difference after accounting for TN status (Figure 3 D).
Finally, the TIME cells showed a trend of increasing AuNPs-PAA-Ctxb content after 12 h (0.38±0.07 pg Au/cell) ( Figure 3E ).
In contrast, Senegalese sole juveniles fed tryptophan supplemented diets showed a trend to decrease plasma cortisol levels when reared at high stocking densities (i.e., 31 kg/m 2 ), which translated in enhanced disease resistance after 39 days of feeding.
Recovery (d15–d28) of peak torque and TTP torque was also not different between groups, but showed a trend for better recovery in the AXA2678 group.
Only one of the characteristics–life satisfaction–showed a trend in the predicted direction such that residents from the small and isolated Palmerston tended to have more positive views of life-satisfaction in later life than inhabitants of the two larger islands.