“showed a trend”

Unfortunately, a CT scan showed a trend of progressive disease (PD) after a month, and the patient was switched to afatinib (40 mg, taken orally, daily).

The results of our study showed a trend of more severe postoperative fatty infiltration in both the multifidus and erector spinae muscle in the COS group than in the MIS group.

Previous US data showed a trend towards higher time to discontinuation of anti-PD-1 agents (pembrolizumab or nivolumab monotherapies) compared to combination therapy 7 , 9 .

DL0410 showed a trend of increasing the number of crosses, search time and distance traveled in the target quadrant.

Hup A-treated ob/ob mice showed a trend toward an improvement in spatial memory (Fig. 3e ).

The women also showed a trend of significantly increased GC risk as the DII increased (p-value for trend = 0.007, 0.004 in Model 1, Model 2, respectively).

Among the other prominent bacterial phyla, we found that the average relative richness of Patescibacteria , Bacteroidetes , and Actinobacteria showed a trend of gradual increase with increased N fertilizer inputs during the first year of the present study, and Patescibacteria and Actinobacteria showed significant positive correlations with soil NO 3 – .

With the increase in NaCl concentration, the growth of hyphae showed a trend of first strengthening and then weakening.

Moreover, subgroup analysis showed that elevated baseline sST2 levels increased the long-term risk of MACEs in the acute coronary syndrome (ACS) population (HR: 1.74, 95% CI: 1.39–2.09) but only showed a trend toward higher risk of MACEs in the non-ACS population (HR: 1.09, 95% CI: 0.87–1.30).

Interspecific communication The results showed a trend for hearing and vision impaired dogs to produce more barks and growls/grunts than sensory normal ones during interactions with their owners.

47 Briassoulis et al suggested that immunonutrition showed a trend to improve colonisation and infection rates in critically ill children but required some changes in immune enhancing formulae for specific age populations. 46 These overall results appear promising that immunonutrition may benefits for patients with paediatric TBI.

A pre-planned interim analysis of OS after a minimum follow-up of 3 years showed a trend in favor of ERd versus Rd (median OS: ERd, 43.7 months; Rd, 39.6 months; HR, 0.77; 95% CI, 0.61–0.97), although OS curves at that time were not fully mature, limiting full interpretation 16 .

Liu et al., through their research on the fruit quality of goji in Ningxia under different phosphorus application levels, found that the transverse diameter of goji showed a trend of first decreasing and then increasing with the application of increasing amounts of phosphorus 17 .

Although subset analysis showed a trend toward a better DFS in favor of erlotinib in patients with activating mutations of EGFR , the difference was not statistically significant.

With the increase of the graphene doping amount, the bulk density of SiC ceramics showed a trend of gradual decrease.

30 Their overall consensus was that IBD patients showed a trend toward higher risks of developing hematological malignancies, more specifically leukemia in UC and lymphoma in CD based on large population-based cohort studies.

APOE 4 non-carriers showed a trend toward greater CSF DHA levels and significantly greater EPA levels compared with APOE 4 carriers.

Exploratory whole‐brain analysis showed a trend toward a significant positive association between sleep duration and FA in several white matter tracts including the SLF, the corticospinal tract, the thalamic radiation and the internal capsule ( p fwe = .056, for further details see Supplementary Material 10 ).

Conversely, subjects with severe LAP showed a trend towards hypomethylation of upregulating genes when compared to healthy controls and subjects with moderate LAP, suggesting increased expression of pro-inflammatory cytokines that promote further periodontal tissue destruction.

Notably, it also emerged that many “old” drugs targeted already targeted proteins; by contrast, new effective drugs used in combined therapeutic treatments showed a trend toward more functionally different targets.

It was shown that after acute administration of sildenafil or vardenafil (1–100 μg/kg, intravenous) PVP remained unchanged or showed a trend towards a decrease.

Moreover, the flow curve showed a trend of gradually decreasing in each pass.

While the mMCP-6-deficient mice only showed a trend for reduced ear thickness at day 14 ( Figure 6 a), a small but significant difference in ear thickness at day 14 was observed and CPA3 −/− mice as compared with wild type littermate mice ( Figure 6 b).

miR-206 showed a trend with higher levels in OPMD (pFDR 0.06) ( Figure 3 B). miR-206 is also upregulated in other muscular dystrophies [ 9 ]. miR-1, a common muscular dystrophy biomarker [ 9 ], was not significantly deregulated in OPMD ( Figure 3 B).

The PAC group showed a trend for less time per day spent sitting compared to the control group (5.6, 95% CI 4.8, 6.4 vs. 8.0, 95% CI 5.6, 10.4, ES = 0.8; β = −2.4, 95% CI −4.9, 0.1) following 12 weeks of intervention.