Although bone marrow Topo-IIa showed a trend of being higher among good responders, it did not reach significance.
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Analysis of sarcomere assembly showed a trend, albeit non-significant, toward increased disarray in E99K-expressing hiPSC-CMs ( Figure S7 ).
Relative to the non-targeting control (NTC), stable knockdown of DVL-1 in MCF7 cells showed a trend of higher E 2 production, although this did not reach statistical significance.
The spherical equivalent power of patients who were prescribed spherical CLs showed a trend of being shifted to be slightly weaker in minus power than for patients prescribed toric CLs ( Figure 5 ).
PAD4 levels in lysates of human liver metastases showed a trend to be increased compared to the adjacent liver based on ELISA measurements and were significantly increased based on immunoblotting (Fig. 3a, b , Supplementary Fig. 6A, B).
However, this group still showed a trend towards an increase of the OB volume over time which can also be seen in healthy controls at this age in other studies (Yousem et al., 1998 ; Buschhüter et al., 2008 ).
The exploratory analyses within the double-wild-type population suggest longer PFS in bevacizumab maintenance is associated with higher AREG levels whereas in the watch- and wait-arm higher AREG levels showed a trend toward shorter PFS (Figure 4 ).
In the pain group, these procedures consisted of 12 ulnar nerve decompressions/transpositions, 6 elbow arthroscopies, 1 removal of medial heterotopic ossification, 1 excision of medial antebrachial nerve neuroma, and 8 revision UCLR, compared with 3 ulnar nerve transpositions, 6 elbow arthroscopies, and 3 revision UCLR in the no-pain group. Medial elbow pain showed a trend toward a higher rate of subsequent revision UCLR (5.6% vs 1.7%), but the trend was not significant ( P = .06) ( Table 3 ).
Moreover, the polar value analyses in this study showed a trend toward against-the-rule astigmatism with increasing age in both refractive and keratometric astigmatism.
Fluvastatin also showed a trend towards down‐regulation of mRNA specific for sST2 in HACM in five donors tested (to 85% ± 24% after 24 h and to 62% ± 38% after 48 h as compared to the respective controls), but had no influence on the levels of ST2L mRNA (data not shown). 3.2 Statin‐induced IL‐33 expression is inhibited by the com
Looking more closely at those primary studies it became clear that one was misclassified ( Melartin et al., 2004 , OR(95%CI) = 2.14(1.06–4.31), the second was a cohort in which only five participants had residual symptoms so the effect could not be adequately assessed ( Ilardi, Craighead, & Evans, 1997 ), and the third showed a trend towards an effect but had a very small sample in which just 19 had residual symptoms ( Kennedy & Paykel, 2004 , n = 59).
In addition, the percent of trapped CD8+ CTL showed a trend towards decreases in the 1D11-treated group with a concurrent increase in infiltrated CD8+ CTL.
MiR-21-5p mimic transfected DCs also showed a trend toward a reduction in CCR7 expression compared to the controls, although a statistical significance was not achieved (Figure 7C ).
The Diuretic Optimization Strategies Evaluation (DOSE) trial showed a trend toward greater improvement in patients’ symptom when using a high-dose diuretic strategy in the first 72 h of hospitalization than when using a low-dose strategy; however, a significantly higher incidence of creatinine level increases was also observed in the high-dose group ( 2 ).
The study showed a trend of improvement in HE in the MARS group compared to that of the control group, but this was without statistical significance.
Except for the strain from Karacay, these strains showed a trend toward dispersing later and less with increasing time in culture, suggesting that there was some selection toward more Killer‐like behavior (Supporting Information Figure S3 ).
From this clustering, 24 proteins showed a trend with higher levels in malaria patients compared to controls (Fig. 2 a).
In our study, the EOFOG had a later AAO of motor symptoms, earlier age at presentation, and shorter disease duration which showed a trend toward significance when compared to the LOFOG group.
Evaluation of transcripts corresponding to the 20 proteins with the highest number of identified spectra ( Supplemental Figure 9 ) and those significantly changing in the secretome ( Supplemental Figure 10 ) showed a trend toward higher expression of periostin and the transcript encoding LG3BP ( Lgals3bp ) after miR-21 mimic and inhibitor transfection, respectively.
The lower oxy-Hb activation in the right DLPFC showed a trend to accentuate gradually with an increase in the severity of psychotic symptoms.
Although the qPCR-based arrays provided a rather limited number of targets, the data showed a trend of alterations to key enzymes involved in GLY, PPP, FAS, and FAO, despite only a few displaying significant changes between the cystic and the control samples ( P in the range 0.0002–0.03), (Supplementary Fig. 5c and Supplementary Data 6 , 7 ).
C-FCM using both FLAER and CD66b also showed a trend for smaller granulocyte PNH clone size than HS-FCM, with a mean difference of 0.7% and 0.9%, respectively ( Fig. 2D-F ).
Additionally, CD160 + cells showed a trend to produce higher amounts of IFNγ compared to the control cells.
(3) The change character of S parameter in candidate steels with increasing irradiation doses was not obvious as the Fe + showed a trend towards a clear saturation.
Among women, the fully adjusted risk among higher occupational class workers was not significantly elevated (Figure 3 ); however, the odds in the service and sales industries showed a trend suggesting a positive occupational gradient pattern (ie, higher risk with higher occupational class; model 5; Table 2 ).