Compared with adults, children generally showed a trend toward better complete responses ( Introna et al., 2014 ; Chen et al., 2015 ).
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Another recent study comparing ICI efficacy with or without KRAS mutations showed a trend toward a better ORR and prolonged PFS in KRAS -mutated NSCLC, with increased benefits for a high rate of PD-L1-positive tumor cells ( 6 ).
Renin showed a trend towards a positive association with incident type 2 diabetes.
Based on the experimental peritoneal cancer index (EPCI) algorithm, six major immune cells showed a trend: the scores of the G1 group with high expression were higher than the scores of the G2 group with low gene expression, interestingly, in the undefined cells, the scores of the G1 group with high gene expression were relatively lower than those of the G2 group with low gene expression (Fig. 6 a).
In addition, pregestational BMI showed a trend to be negatively associated with GWG in the underweight category, although this did not reach statistical significance.
Within the LCNEC subgroup, BRAF mutations (p=0.34, Figure 3C ), but not RB1 mutations (p=0.56, Figure 3D ), still showed a trend of increased survival.
Our meta‐analysis showed a trend of greater reduction of the negative effects of oiling with increasing taxonomic diversity but was more limited for genetic diversity.
The change in the categorized insomnia diagnosis (worse, unchanged, improved) showed a trend toward improvement of insomnia status in the BB-group from baseline to posttreatment, whereas the opposite was the case for the control group, though not significant.
However, the LGR5 expression only showed a trend associated with larger tumor size, lymph node metastasis, and higher TNM stage because of the small sample size.
Results The data from TCGA indicated that let-7d was down-regulated in rectum adenocarcinoma samples, whilst ABCC2 was showed a trend of high expression and its overexpression hinted to worse overall survival of rectum adenocarcinoma patients.
Recent studies found that following TCR activation upon engagement of the associated ligands, this protein network showed a trend for triggering phase separates, which was dependent on the formation of membrane-bound clusters, including Grb2 and SOS proteins, involved in intracellular domains of TCR ( 31 ).
Of note, while AChRγ mRNA showed a trend toward upregulation (Fig. 3 a), histological NMJ denervation was not observed in fast-twitch EDL muscles (Fig. 3 d,e), suggesting that denervation of NMJs occurs predominantly in slow fibers as a consequence of TFG deletion in the innervating nerves.
50.9 ± 68.7 for 18 F-rhPSMA-7.3) showed a trend towards higher tumour uptake values for 18 F-rhPSMA-7.3 but without statistical significance ( p > 0.05, Fig. 1 , Table 3 ).
The median time for progression was 11.9 and 11.0 months, respectively in patients received combined chemotherapy with pyrotinib and standalone pyrotinib therapy, which showed a trend for longer PFS with patient group receiving combined with chemotherapy, however, there was no statistical significance ( p = 0.4989) (Figure 5 ).
We showed a trend to reduce HRV‐induced gene expression in epithelial cells, but only in fibroblasts, these changes were significant.
In addition, a recent meta-analysis compared the studies with an interval of > 2 weeks versus < 2 weeks and showed a trend towards lower leakage percentages for > 2 weeks, whereas no reduction in leakages was seen for < 2 weeks [ 22 ].
Although interferon related signatures showed a trend to be enriched in MTDH KO tumorspheres, the overall enrichment scores are much lower as compared to that from in vivo tumor samples ( Extended Data Fig. 1h ), indicating that the enriched interferon-related signatures are mostly caused by changes in the tumor microenvironment.
Similarly, CD4 + and CD8 + T cell subsets showed a trend toward increase during disease progression, with a significant increase of IFN-γ + CD4 + T cells in an age-dependent manner (Fig. 4 C to E).
identified a 42.4% incidence of vasospasm using transcranial Doppler following cranial gunshot wounds in patients aged 15–50 years [ 6 ], and showed a trend towards favorable neurological outcome in patients without vasospasm.
The low-dose fosfomycin group showed a trend of a reduction in the kidney index, but the difference was not statistically significant ( p > 0.05). 3.4.2.
The correlation coefficients for the groups with a less close relationship (in comparison with partners) or having a different address/living in a different town (compared with sharing the same address with the patient) showed a trend towards higher correlation coefficients.
The only placebo-controlled, randomized trial also showed a trend towards more efficient inflammation resolution with adjunctive NSAID treatment [13] .
We found that bacterial richness and alpha-diversity showed a trend toward increasing as disease severity increased; however, alpha-diversity dropped in those patients who had the most severe COVID-19 disease.
Discussion The patients in the present study with nonfibrotic HP who did CAA did not experience recurrence or develop fibrosis and sustained their clinical improvement, whereas those with fibrotic HP not doing CAA showed a trend towards poor prognosis.
Trametinib was also associated with a four-fold increase in the probability of response to therapy, and showed a trend toward an overall survival benefit, despite the 68% of patients in the standard-of care group who crossed over to trametinib.