Barely Significant
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“showed a trend”

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showed a trendP = 0.0591.2× alpha
Similar data on medication overuse were unavailable from the US trial, but a secondary analysis was performed and showed a trend towards significant group differences ( P = 0.059). 56 In the European trial the responder rate of at least 50% in reduction of migraine days was significant for topiramate (22% vs 0% P = 0.012), but not in the US trial in which only the under 25% reduction in migraine/migrainous days responder rates showed significance. 57 Patients’ disability and quality of life evaluation results were different in both trials.
showed a trendp = 0.0591.2× alpha
11 C-deuterium-L-deprenyl PET region of interest analysis Comparisons of four groups (presymptomatic ADAD carriers, MCI PIB+, sAD and ADAD non-carriers) using Kruskal-Wallis tests in each of 11 ROIs (except for the cerebellum), showed a trend toward statistical significance for the anterior cingulate cortex, the thalamus and the hippocampus (p = 0.059–0.069) ( Supplementary Table S1b ).