GO term analysis demonstrated a significant upregulation of DNA damage repair pathways in the D/KO enhanced reprogramming group including DNA repair, homologous recombination (HR), non-homologous end joining (NHEJ), base excision repair (BER), mismatch repair (MMR), nucleotide excision repair (NER), and alternative end joining (AltEJ), while interstrand crosslink repair (ICR) showed a trend towards upregulation.
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The interaction energy between a water molecule and the surrounding derivative molecules also showed a trend where beyond 325 K there is a steady increment in the value (Fig. 6 e).
The UVMR results showed a trend towards an increased FI in total leukocyte count (β = 0.016, 95% CI, –0.003–0.0035), neutrophil count (β = 0.019, 95% CI, 0.019–0.04), and basophil count (β = 0.009, 95% CI, –0.021–0.039), but this trend was not statistically significant in the IVW and sensitivity analyses.
1 A, the hydrogen production of each test group showed a trend of increasing and then decreasing with time, and there was a significant decrease in gas production after 12 h.
Conversely, behavioral analyses showed a trend for the losartan group versus placebo to be faster at identifying novel images as animals/landscapes, indicating a visual processing rather than a memory encoding advantage, although this was not statistically significant.
Case 3 A 62-year-old man who underwent laparoscopic left nephrectomy for T1b left renal cell carcinoma two years earlier showed a trend toward an enlarged right renal cystic lesion on imaging studies.
Interestingly, in a new Cyberball paradigm using partial exclusion by only one of the two co-players, BPD patients showed a trend towards punishing the excluder, which is in line with a fight-and-flight response.
Regarding changes in depression classification, logistic regression analysis showed a trend towards a significant treatment effect for all the included NSAIDs compared to placebo.
However, those without a diagnosis showed a trend where BDNF levels increased over time [ 63 ], suggesting BDNF is reactive to stress and secretion may increase over time as the initial impact of stressors lessens.
Except for the samples at 110 °C, the leakage current of the samples at other temperature conditions showed a trend of first decreasing and then increasing with the increase in sputtering times.
Under drought stress, the expression of the genes encoding to most enzymes in the TCA cycle of J432 and Z23 showed a trend of first increasing and then decreasing.
Effects of Different Nitrogen and Phosphorus Fertilization Treatments in Ratooning Rice on Greenhouse Gas Emissions During the ratooning season, methane (CH 4 ) emissions showed a trend of initially increasing and then decreasing, with a peak around 25 days after the first season’s harvest ( Figure 2 ).
Furthermore, the ratio between day 7 LSM and baseline showed a trend, although not significant, of increment in ALF patients with poor prognosis (Supplementary Fig. 3 A , http://links.lww.com/CCX/B306 ).
Note also, although not all disease markers that associated with severity also showed a trend against the duration of symptoms, they all showed a remarkable stable distribution when stratified by total disease days ( S2 Fig ).
It was found that GRA and RAE, the most abundant glucosinolate in broccoli and radish sprouts, respectively; showed a trend of increasing, then decreasing with the increasing of UV-A intensity, and it reached the highest level at 12 W UV-A intensity, which was 2.99 and 2.84 times that of the control.
While there were no significant differences in the phylum composition among the different brain regions, Proteobacteria showed a trend of being more abundant in the frontal cortex and hippocampus compared to the hypothalamus (statistically insignificant).
95 Interestingly, shTDP-43 showed a trend of genome-wide loss of interactions, and enhancer R-loop/5hmC depletion resulted in the downregulation of targeting genes.
The B&A plot also showed a trend towards a higher difference in SDM-Q scores (Q-9 minus Q-Doc) with increasing mean scores.
The present results showed a trend of increased mucosal inflammation within the mucosa of the ET in MEE cases.
Low femoral neck cut showed a trend toward statistical significance.
In addition, we considered the history of EET as a predictor of future EET and showed a trend toward higher future willingness to undergo EET, but this was not significant in multivariable regression analysis.
Total vessel density of small and total vessels (TVDs, TVDt), De Backer score showed a trend towards an increase that was not statistically significant at the Friedman test for repeated measures (Fig. 1 , Additional file 2 ).
In summary, the analysis of particular subgroups according to different criteria led to the conclusion that (1) studies using the PTS technique reported significant improvements in all 3DGA parameters compared with no-PLS, while studies using the PTA technique showed a trend toward improvement that was not statistically significant; (2) as in the overall analysis, high-quality studies showed more improvement in stance-phase gait parameters, but not in KFC; and (3) studies with longer follow-up revealed no significantly superior improvement in KFIC, KFC, and GDI, no significant increase in APT, but a significant improvement in mKFSt and reduction in pKFSw for in the PLS group.
The MONARCH-3 trial showed a trend towards longer OS by adding abemaciclib to an AI (67 months versus 55 months, HR 0.75, 95% CI: 0.58-0.97) [ 21 ].
In clustering analysis, STS associated with the MDM2 (amp)/ TP53 (WT)/ RB1 (WT) cluster (#6), which generally corresponds to DDLPS, showed a trend toward lower eribulin efficacy.