While ABCG2 (12M/141Q) conferred the highest resistance among the tested variants, the ABCG2 (12M/141K) haplotype showed a trend toward higher mitoxantrone resistance than the ABCG2 (12V/141Q) (WT) ( p = 0.066), suggesting a haplotype-specific effect.
Group-level statistics performed on the MMN time window (i.e., 70–185 ms, based on CTR and OFC group condition contrasts) showed a trend-level reduced MMN for OFC patients compared to controls in a time window between 81 and 106 ms [positive cluster: t (25) = 588.31, p=0.066, 34/64 channels].
Plasma levels of glucose, fructose, pyruvate, and lactate were significantly lower in septic versus control mice, while circulating sucrose levels showed a trend toward lower concentrations ( P = 0.066) ( Figure 1, B–F ).
At 6-month follow-up, patients with signs of metabolic syndrome showed a trend towards lower PHES compared to patients without these manifestations (− 6.3 ± 1.2 vs. − 3.6 ± 0.6; 95CI = − 0.2–5.6; p = 0.066).
Our interaction analysis also showed a trend ( P = 0.066) suggesting arthralgia might modify the TNFi vs nbUVB treatment effect.
CMR and discrepancies between iFM Krakau -CO and TD-CO Reduced LV and RV stroke indexes were the only variables that showed a trend toward a deviation of > 20% between iFM Krakau -CO and TD-CO ( p = 0.066 and p = 0.052 in patients with no deviation vs. a ratio > 1.2, respectively).
Results Pilot Study and Power Calculation In the pilot study, comprised of tissue samples from Stanford and Rush, B-cell density in younger subjects (mean = 0.9 cells/cm 2 ± 1.5.) versus older subjects (mean = 3.0 cells/cm 2 ± 2.6) showed a trend (p = 0.066) indicating that B-cells might increase with age.
Finally, the piglets from supplemented mothers showed a trend for a higher weaning weight ( p = 0.066) and, specifically, piglets with birth weights above 1 kg showed a 7.4% higher weaning weight ( p = 0.024).
Univariate analysis showed a trend toward higher recurrence rates in females ( p = 0.066), advanced pN stage ( p = 0.1) and in cases with perineural invasion ( p = 0.095), without reaching statistical significance (Table 4 ).
Corn-based SFD showed a trend towards a dose-response, with Corn20 having slightly higher breath hydrogen response when compared to Corn10 and Tapioca10 ( p = 0.066 and 0.052, respectively). 3.3.
The MRS data showed a trend of NAD + remaining stable or decreasing slightly in Young hearts with higher workload but increasing in Old Control hearts ( p = 0.066) (Figure 4e ).
Univariate analyses showed a trend for H3K9Ac, when LINE-1 methylation was high, with local recurrence-free survival ( P =0.066) ( Table 3 ).
Patients receiving factor XIII substitution showed a trend toward a decreased need for transfusions after substitution (0 [0, 5] vs. 3 [1, 6], p = 0.066).
Clinicopathological Comparison Between nPD-L1 Positivity and Negativity In our study, the nPD-L1-positive group showed a trend toward an older median age (48 y vs 42 y, p=0.066) and higher PINK score (45.4% vs 37.8%, p=0.071) and a trend toward a lower CR rate after initial treatment (47.7% vs 67.6%, p=0.073) ( Table 2 ).
Our results showed that none of these genes showed expression changes at a significance level of 0.05 even though BDNF and CRHR1 showed a trend toward a decrease (both at P = 0.066; Supplementary Figure S7 ).
The hypermetabolic group had a shorter survival time in normal-weight patients ( p = 0.009) but showed a trend of longer survival time in the malnutrition group ( p = 0.066) (Fig. 1 ), which was also seen in the log-rank test for time since this admission (Supplemental Fig. 1 ).
Only reduced renal function showed a trend toward an impact on OS ( P = 0.066) but not on DSS ( P = 0.334) survival in the subgroup of patients with non-muscle-invasive BC (MIBC).
Changes of total lymphocytes during the study period after the administration of SBRT showed a trend towards statistical significance using Friedman one-way ANOVA ( p = 0.066).
Univariate analyses also showed a trend to confirm this effect for PD‐L1 ( p = 0.066) but not for the other markers on lEVs (Suppl.
B -Tlr7 –/– mice aged for 25 weeks after chimerization showed a trend toward reduced glomerulonephritis ( P = 0.066) ( Supplemental Figure 4 and Supplemental Table 3 ).
rate control in the primary endpoint of all-cause death or HF event but showed a trend in a similar direction as the other trials [23% vs. 33%, HR (95% CI) 0.71 (0.49–1.03), P = 0.066; n = 411].
The interaction of condition*order had no effect on NREM sleep (F 1,42 = 0.006, p = 0.939) but showed a trend-level effect on REM sleep (F 1,42 = 3.562, p = 0.066).
The CRRT ≥7 days group showed a trend toward more long-term dialysis when they were compared with patients who suffered AKI but did not receive CRRT (aHR 2.72 [0.94–7.87], p = 0.066, Additional file 1 : Figure S1).
The effect of the experimental week on blood insulin and glucagon in dairy cows was extremely significant ( p < 0.01), and the effect on blood amylase content showed a trend ( p = 0.066).
pBD2 showed a trend of an increased IL-2 content compared with the control group ( p = 0.066) but had no significant impact on the levels of pro-inflammatory cytokines TNF-α and IL-6 ( p > 0.05).