Interestingly, four of five patients with febrile reactions to ICB belonged to the subset of patients with high levels of T cell infiltration, and high TiL levels showed a trend toward improved PFS (p=0.07, online supplemental figure S5B ).
The LAAO group showed a trend toward having a lower estimated mRS scores at baseline to those of the NOAC group (p=0.07) and scores at 12 months post-stroke were significantly lower in the LAAO group (p<0.01), even after adjusting for several variables, including CHA 2 DS 2- VASc score, HAS-BLED score, age, gender, and other cardiovascular risk factors.
The GWI + VNS sham group showed a trend ( P = .07, NS ) toward a reduced frequency of visits to the novel place object.
Interestingly, 4-months-old Fus ΔNLS/+ mice showed a trend towards longer interaction with the intruder mouse as compared with Fus +/+ mice ( p = 0.07) (Fig. 2a ), that was significant at 10 months of age (Fig. 2b ) and persisted until 22 months of age (Fig. 2c ).
Positive PD-L1 staining determined at a threshold of 1% showed a trend towards improved survival in the entire cohort (70.3% vs. 57.4%, p = 0.07) in univariate analysis ( Figure 2 ).
We found a trend towards an increase in the TNFR1 + classical monocyte cell population [Ctl: 1.87% (1.21–2.52) and IS: 2.54% (2.07–4.27), U = 51.5, p = 0.07] in ischemic stroke patients compared to controls, whereas the TNFR1 + intermediate cell population showed a trend towards a decrease [Ctl: 1.35% (0.44–2.52) and IS: 0.49% (0.13–1.04), U = 52, p = 0.07] ( Figure 3 f).
Differences in IL-6 concentrations were significant for Day ( P < 0.01), and for the Day X SBO interaction ( P < 0.01), and showed a trend in the Treatment X Day interaction ( P = 0.07) ( Table 1 ).
Furthermore, the parameter Conn.D also showed a trend towards a significant main effect of microgravity ( p = 0.07) and a significant TPO × microgravity interaction ( p = 0.008).
IFITM3 rs34481144 A-allele showed a trend ( P = 0.07) for an increased risk of severity of COVID-19 (OR: 1.81, 95% CI: 0.95–3.43). 4.
It is found that the abundance of Bacteroidetes varied most significantly ( p < 0.05), the abundance of Proteobacteria showed a trend of variation ( p < 0.07) between the control group and excessive DR group, and the abundance of Firmicutes and Actinobacteria did not differ significantly among groups ( p > 0.05).
Further, male EAE mice showed a trend towards worse cardiac function at 2 months of recovery compared with at 1 month (LVEF: 49.53 ± 2.063 vs 54.57 ± 1.700, respectively; p = 0.07; LVFS: 24.82 ± 1.263 vs 27.82 ± 1.063, respectively; p = 0.08).
IL-13 and IL-25 were not significantly associated with any specific irAE but showed a trend toward higher fold change for enterocolitis irAEs ( Figure 4, C and D ; P = 0.07 and P = 0.05, respectively).
Undergoing multivariate analysis, the average steady-state colistin concentration showed a trend towards statistical significance for acute kidney injury occurrence (OR 4.36; 95%CI 0.86–20.0; p = 0.07—Sorlí et al., 2019) [ 125 ].
Western blotting showed a band corresponding to the predicted 43‐kDa molecular weight for asporin in rToF‐PVR samples and showed a trend toward increased expression ( P =0.07) compared with RV donor samples.
Consistent with the previous finding, however, and despite the lack of general change in spatial bias highlighted above, improvement in self-ratings showed a trend towards statistical significance in predicting post-intervention bias ( β = -0.18, p = .07) that was absent in the WMT ( β = 0.07, p = .53) and WL ( β = -0.06, p = .55) groups.
Moreover, the presence of >30% TIL was seen only in patients who experienced a clinical benefit (25% vs 0%, p=0.22) and the tumors of patients who experienced a clinical benefit from therapy showed a trend towards greater TIL compared with those who lacked clinical benefit (27% vs 11%, p=0.07), suggesting TIL levels may serve as both a prognostic and possibly predictive biomarker, requiring further validation ( online supplemental figure 2 ).
SP‐11 showed a trend toward attenuating the colonic hyperpermeability induced by PRS (0.95 ± 0.05 vs 0.71 ± 0.11 nmol/cm 2 /h, respectively, P = .07; Figure 3 ). 3.3 Gut transit After stress induction, colonic mean retention time significantly decreased in comparison with non‐stressed animals treated with saline (9.85 ± 0.65 vs 3.75 ± 0.52 hours, respectively, P < .01).
1.3%, p = 0.001) and showed a trend towards fewer major ischemic events (0.4% vs. 0.7%, p = 0.07).
Furthermore, cl‐OPN/FL‐OPN showed a trend ( P =0.07; N=28; Wilcoxon matched‐pairs signed rank test) to be higher in plasma from the coronary sinus versus plasma from the radial artery, indicating that osteopontin might be cleaved locally in the pressure‐overloaded human heart.
When analyzed globally, beta diversity showed a trend towards a change in the microbiota profile between D0 and W6 in the FMT ( p = 0.07) but not the sham ( p = 0.7) group (Fig. 3 b).
In cardiac nerve bundles, %AAT of 8-OHdG-ir showed a trend (p < 0.07, η p 2 = 0.367) toward an overall effect of treatment, which was significant when treatment was considered in combination with region (treatment x region: %AAT, p < 0.04, η p 2 = 0.309; OD, p < 0.03, η p 2 = 0.312).
Furthermore, the highest of the specific IgE values at baseline to any of the foods in the participants’ OIT showed a trend to be important for the study outcome in the placebo arm (P = 0·07, FDR adjusted P = 0·19, appendix p 7), while this was not the case in the omalizumab arm.
Plasma levels of IL-4 were associated with the levels of intact proviral DNA (r=0.37, p=0.009), and the other main Th2 cytokine, IL-13, showed a trend towards a positive association with intact proviral DNA (r=0.26, p=0.07) (Table 1).
Intervention had no effect on time to first exacerbation (HR 0.65, 95% CI 0.21 to 2.07, P = .24), but showed a trend toward a 39% decreased frequency of exacerbations (RR = 0.61, 95% CI 0.35 to 1.03, P = .070) for the adjusted models, respectively.
However, one metabolite, serum N,N-Dimethylglycine, showed a trend (OR = 0.548, p = 0.070) indicating that higher values were associated with an increased chance of being a Non-responder.