Treatment of polarized ARPE-19 cells with 100 nM ZK for 3 h showed a trend (p = 0.07) to increase BECN1 expression in low autophagy-/UPR-related gene-expressing cells (Fig. 6 c) but significantly decreased BECN1, MAP1LC3B, mTOR, ATF6, DDIT3, EIF2AK3 and HSPA5 expression (Fig. 6 a,c,d,f,j,k,m) in high autophagy-/UPR-related gene-expressing cells.
The result also showed a trend of significant effects at the Fz ( F (2,36) = 2.861, p = 0.0703) and Cz ( F (2,36) = 3.047, p = 0.06) over the midline.
In addition, the difference in VAS changes from baseline between the FSG and FNG subgroups showed a trend of decreased VAS improvements for FSG ( P = 0.0703).
Of note, CifB showed a trend for reduced w Mel density in the germline compared to that in the control ( N Cont = 27, N CifB = 30, P = 0.0704).
Meta-analysis showed a trend toward an increased risk of PVT in neonates with sepsis ( p = 0.0705).
The age of patients at the study time showed a trend to negative correlations with both average GCIPL thickness (R = −0.15, p = 0.0706) and GCIPL lower thickness (R = −0.15, p = 0.0759).
The distributions of the GSK3B haplotypes (−50T/C and −1727A/T) showed a trend for significant difference between the lithium nonresponders and responders (global P =0.07074).
No difference in UAER was observed between C57BL/6 male and female mice, but the female NTN mice showed a trend towards increased UAER ( P = 0.0708 at 6 weeks and P = 0.0746 at 10 weeks, data not shown).
Group B cases also showed a trend toward less frequent SF3B1 mutation compared with WT ( P = 0.0708) (Table 3 ).
Among CTR and control patients with myopia, while A CCC showed a trend of greater decrease in the control subgroup than in the CTR subgroup from 1 week ( p = 0.0709) to 1 month ( p = 0.0529) postoperatively, it was significantly smaller in the control subgroup than in the CTR subgroup at 3 months ( p = 0.0113) after surgery.
Clinical parameters such as the Charlson Comorbidity Index showed a trend toward higher values in the slow gait speed group (4.0 [3.0–5.0] vs. 2.0 [0.0–4.0], p = 0.071) but did not reach statistical significance.
Although C-peptide levels showed a trend towards reduction (p = 0.071), fasting glucose levels, lipid profiles, and estimated glomerular filtration rates remained unchanged.
However, on incongruent trials with reward distracters, the amygdala response was significantly positively correlated with the right IFG/insula response, r = 0.553, p = 0.050, and showed a trend toward a positive association with the left IFG/insula response, r = 0.516, p = 0.071.
Overall in the 11 NUCs treated patients MiR-B-Index showed a trend to improve [BL vs post-T-FU median values −5.86 (−13.39/6.57) vs 0.12 (−8.41/9.46), p = 0.071].
Time spent in close inspection was significantly affected by the block ( p = 0.014) and showed a trend towards a condition effect ( p = 0.071, both species tended to show more close inspection towards the mirror than the control).
While the ECPR group showed a trend toward better 30-day survival, the difference was not statistically significant compared to the CCPR group ( p = 0.071).
SGM cancer survivors with cardiovascular disease showed a trend ( p = 0.071) toward lower odds of living in a state with protective policies (AOR: 0.89; 95% CI: 0.78–1.01).
The overall model of multiple regression analysis for the predictive value of change in the FEV domain “hunger” score between t0 and t4 and the binary variable psychiatric medication yes or no for weight change was not statistically significant ( R 2 = 0.14; F (2, 30) = 2.49; P = .10), but showed a trend with the biggest influence for the change in the domain “hunger” ( β = 0.325; T = 1.87; P = .071; CI (Confidence Interval) (−0.03; 0.77)).
The hip BMC intervention-by-time interaction showed a trend toward statistical significance ( p = 0.071).
In patients with low TIL levels, the stromal CD8 + IC/CD4 + FOXP3 + IC ratio showed a trend toward being higher in the pCR group (5.9 ± 0.8 vs. 3.2 ± 1.9, p = 0.071).
The Parker mobility score showed a trend ( p = 0.071 ) of being lower in patients with infections.
However, cluster sizes in the networks from the 5–7 RTI group showed a trend towards less increase over time compared to clusters from networks from the 0–2 RTI group (negative binomial GLM: 5–7 RTI group estimate = − 0.3, p = 0.071), which coincided with a higher number of clusters retained in the 5–7 RTI networks.
The experience of financial problems during the pandemic was significantly associated with a 0.29-point reduction of perceived family happiness after controlling for other factors (Model 1: Beta = −0.29, bootstrap SE = 0.12, P = 0.014), whereas the experience of close persons died of COVID-19 infection only showed a trend of association without reaching the threshold of statistical significance (Model 1: Beta = −0.29, bootstrap SE = 0.16, P = 0.071).
However, the change in SWE compared to T0 showed a trend at T1 (7.7 ± 15.7 kPa vs −4.1 ± 12.0 kPa, P = .071) and was significantly different at T2 between sigmoid endoscopic responders and non-responders (9.9 ± 11.5 kPa vs −8.1 ± 11.4 kPa, P = .002; Table 6 , Figure 4 ). 3.5.2.
Additionally, the RE group showed a trend of higher milk fat content compared to the CON group ( P = 0.071) ( Table 2 ).