Additionally, ALP staining and activity assays revealed significantly higher ALP activity in the up‐LNC000133‐Exo group compared with the control group, while the sh‐LNC000133‐Exo group showed a trend toward inhibited ALP activity ( p < 0.05) (Figure 5C,D ).
Transcriptomic analysis showed that 48 steroidogenesis pathway genes in the livers of HC mice exhibited significant expression changes ( p < 0.05), and 42 of these genes showed a trend of reversal after GP treatment, with 32 genes being significantly reversed ( p < 0.05).
All variables that were significant (p < 0.01) or showed a trend toward significance (p < 0.05) in univariate analyses were included in the regression analyses (details of the included variables are presented in the results section).
Family communication satisfaction regarding the illness showed a trend toward near significance (p>0.05), with HD patients being more satisfied (mean=2.1, SD=1.2).
With the addition of CSN, the WS value of the pH-responsive film showed a trend of decreasing ( p < 0.05).
Notably, improvement at the tongue base in the head rotation position showed a trend toward improvement (overall P = 0.050 ), suggesting a possible treatment effect in this subgroup.
Yolk height, thick albumen height, and haugh units were unaffected by the treatment, while thin albumen height showed a trend towards reduction in the PRSE group at weeks 47 and 49 (P = 0.05).
However, a history of AF showed a trend toward lower levels (MR 0.90, 95% CI 0.81–1.00, P = 0.05).
The PCR group also showed a trend toward shorter hospital stays (median 7 vs. 8 days; p = 0.050) (Table 6 ).
Supplements Seventy per cent of BLCF infants were given multivitamin or vitamin D supplements, compared with 48 % of SW infants, which showed a trend towards statistical significance ( P = 0·05).
Compared with the C group, the E group showed a trend of a significant decrease in triglyceride ( P < .05), lymphocyte count ( P < .05), fasting glucose ( P = .07), and plasma MMP-2 ( P < .05), while MMP-9 ( P < .05), hydroxyproline ( P < .001), and muscle strength ( P < .01) significantly increased.
Texture and aftertaste acceptance showed a trend similar to that of sweetness intensity ( p < 0.05).
Although there was no notable disparity in the levels of HDL‐C between the two groups, the levels of TC and LDL‐C in the SA group showed a trend of increase compared to the NSA group, with certain time points showing significant differences (TC, at the fourth to eighth month, p < 0.05; LDL‐C, at the fourth, fifth, and eighth month, p < 0.05).
A high quotient (≥3.0) was linked to a 2.3-fold higher risk of rejection (95% CI 1.2–4.5; P =0.014) and showed a trend toward worse graft survival (HR 1.9; 95% CI 1.0–3.6; P =0.050).
In addition, we evaluated changes for genes NefH and Ngf, also involved in axonal function, growth, maintenance and neuron survival ( Ryden et al., 1997 ; Hayakawa et al., 2012 ; Turney et al., 2016 ; Fornaro et al., 2020 ) although changes between vehicle and boldine SCI samples were not significant and only showed a trend ( Supplementary Figures 9G, H ; p > 0.05).
Transport/geographic barriers showed a trend toward being more common in LMIC studies ( p = 0.05).
Notably, putrescine levels were significantly higher in the probiotic group at both weeks 4 and 8 ( P < 0.05), whereas glycine levels showed a trend toward increase at week 12 ( P = 0.050), following the probiotic-only phase.
Infantis showed a trend characterized by a high APC from 2008–2010 (p < 0.05) followed by a lower APC from 2010–2018 (p > 0.05) (see Suppl.
At 18 WPV, both CD4 + ( Figure 1 A) and CD8 + ( Figure 1 B) T cells showed a trend increase ( p > 0.05) in the frequency of IFN-γ mRNA positive cells in both MLV and Combo vaccinated groups compared to control animals.
The genus Butyricicoccus showed a trend toward lower abundance in the Control group but did not reach statistical significance after FDR correction ( P < 0.05, q -value = 0.055) ( Figure 4B ).
While PPRH2 showed a trend toward greater single-agent activity, these differences were statistically significant only when comparing DOTAP to PPRH2 ( p < 0.05) and Sc9 to PPRH2 ( p < 0.01) ( Figure 3 A), indicating that this concentration was appropriately sub-cytotoxic for combination studies.
MiR-21 showed a trend of upregulation (>1.6-fold, p<0.05) only at 12 h post-OGD.
After SLBZP treatment, however, these parameters showed a trend towards normal levels ( p < 0.05).
Those who had reported more difficulty in attending 'suitable' courses showed a trend significant at the p < 0.05 level for less confidence in arthroscopy and sports medicine.
Compared with the FMT‐spost group, transplanting feces from pre‐inoculation group also showed a trend of shrinking tumor volume, though not reaching the statistic threshold ( P > 0.05).