“showed a trend”

This showed a trend towards improved survival for patients with baseline sSema4D < 41.74 ng/mL (log-rank 4.045, p = 0.044; Figure 3 B).

Although we did not observe a 3‐way interaction of group × condition × response ( F (3,105) = 2.041, p = 0.113, partial η 2 = 0.055), we observed that irrespective of the stimulus condition the low perceivers showed a trend towards increased confidence in reporting the absence of the target compared to the high perceivers (significant group × response: F (1,35) = 4.382, p = 0.044 partial η 2 = 0.111, with post hoc pairwise comparisons yes: F (1,35) = 0.698, p = 0.409, partial η 2 = 0.020; no: F (1,35) = 2.696, p = 0.110, partial η 2 = 0.072) (Figure 3E ).

At 10 mo, Rer1 showed a trend towards a significantly reduced expression in 5XFAD female mice (Fig. 5 K) (Genotype: F(1,10) = 5.315, p = 0.044; RGs: F(2,20) = 0.402, p = 0.674; Genotype*RGs: F(2,20) = 0.537, p = 0.593).

Upweighted genes for subcortical-cortical connections showed a trend for enrichment for genes associated with increased PD risk (15 shared genes, p = 0.044 (uncorrected for multiple comparisons), Supplementary Results 6 ) but not those associated with AD (p = 0.762) or DLB (p = 0.998).

Consistent with the results of previous studies, the patients with primary giant GISTs who underwent surgery after IM treatment in this study showed a trend of better OS ( P = 0.044) than those who underwent IM alone.

Positive surgical margin rates showed a trend toward improvement over time ( χ 2 = 12.9, df = 6, p = 0.044).

In contrast with the NHANES data, the current study showed a trend for decreased ST with increasing age for women up to 70 years of age ( p = 0.044).

Patients with VaMCI showed a trend toward higher ratio of 8-ISO to LPH compared to that of CAD controls (0.15±0.66 versus – 0.05±0.45 (F (1, 104) = 4.145, p = 0.044) ( Fig. 1 ).

On the other hand, mean pre-treatment HbA 1c was higher in mucinous (5.9% ± 0.4%) compared with non-mucinous (5.7% ± 0.3%, P = 0.007) adenocarcinomas and showed a trend to increasing concentrations from early (5.6%) to both advanced (5.8%, P = 0.044) and metastatic (5.8%, P = 0.020) CRC stages in non-diabetic patients (Anova test: F = 3.9, P = 0.021) (Figure 1 ).

Similarly, patients with high SII (above median) showed a trend toward worse survival, though with borderline significance (log-rank test, p = 0.044) (Fig. 6 ).

The Kaplan–Meier survival curve also showed a trend toward poorer survival in patients with COVID-19 and diabetes whose leukocytes were > 5.37 × 10 9 /L than for those whose leukocytes were ≤ 5.37 × 10 9 /L ( P = 0.0448), and the HR was 1.784 (95% CI 1.014–3.140) (Fig. 1 c).

Among females aged 16–18 years, infection was more frequently associated with attending college and rural schools, and showed a trend towards increasing prevalence with increasing social deprivation ( P =0.045).

A recent meta-analysis, taking into consideration twenty-eight trials enrolling 11,880 patients on DPP-4 inhibitors, showed a trend to reduced risk of fractures (odds ratio [MH-OR] 0.60, 95%CI 0.37–0.99, P = 0.045) in these patients compared to those on placebo [ 325 ].

In contrast, patients with a dilated left atrium (LAVi ≥ 40 mL/m 2 ) showed a trend toward worse outcomes with propafenone, including higher 1-month mortality (HR 3.6, p = 0.045) and slower cardioversion (median 18 h vs. 6.4 h with amiodarone, p = 0.05) ( 56 ).

And the 12-month DoR rate in OG and CG was 50.0% (95% CI: 27.1–69.2%) and 22.2% (95% CI: 3.4–51.3%), which showed a trend toward marginal statistical significance ( χ 2 =4.034, P =0.045).

The effect of the global index of myelin content change on EDSS only showed a trend toward statistical significance ( p = 0.045; beta‐coefficient = 0.53; Table 2 ; significance confirmed with ordinal regression: p = 0.04).

Analyses on specific metabolizer phenotypes showed a trend for higher frequency of CYP2D6 ultrarapid metabolizers (UMs) in remitters compared with non-remitters in patients with TRD (χ 2 = 4.76, p = 0.045), but not in patients without TRD (χ 2 = 0.02, p = 1.00, Supplementary Table S9 ).

In addition, exploratory biomarker analyses, including the assessment of EGFR gene copy number by FISH, EGFR and p-AKT protein expression by IHC, EGFR, K-RAS and D-RAF mutational status, showed a trend towards a better survival outcome for gefitinib in patients with high EGFR-gene-copy number (HR 0.61 for high copy number and HR 1.16 for low copy number, P = .045), while patients with EGFR mutations obtained higher RR than wild-type patients (37.5% versus 2.6%) [ 31 ].

Further analysis showed a trend towards a higher utilization of non-excisional techniques in males ( p = 0.045) and a significant association between co-morbidities and the use of excisional techniques ( p = 0.049) (Table 1 ).

The top differentially expressed protein was potassium voltage-gated channel subfamily Q member 3 (KCNQ3) (Log 2 FC = −0.481, p = 2.10 × 10 −09 , FDR = 5.93 × 10 −06 ), which also showed a trend to downregulation in Western blot ( p = 0.045, Bonferroni adjusted p = 0.090).

More TILs (cut-off ≥ 300/mm 2 ) in patients with MBC showed a trend for better prognosis (HR, 0.26; 95%CI, 0.07–0.97; p = 0.045), and this trend become stronger in MBC with squamous cell cancer (HR, 0.07; 95%CI, 0.008–0.64; p = 0.018).

However, we did not observe a significant prognostic impact of HR FISH as defined by the R2‐ISS classification in NDMM patients, and in RRMM, HR FISH showed a trend toward shorter PFS (median: 6.5 vs. 11.6 months, p = 0.045) and OS (median: 19.7 months vs. not reached, p = 0.11) (Supporting Information S1: Figure S2 ).

D1R-KO mice also showed a trend for lower performance compared to D1R-dWT mice (main effect of animal group, p = 0.045; D1R-KO vs.

Hierarchical multivariable logistic regression analysis accounting for regional differences revealed that the presence of chronic kidney disease was associated with higher rates of statin non-prescription (OR 1.87, 95% confidence interval, 1.69–2.08, p value <0.001), and higher age (per 1-year increase) showed a trend for prescription of low-intensity statin (OR 1.00, 95% confidence interval, 1.00–1.01, p value = 0.045) within the subset of PCI patients (N = 4,853) enrolled after the year 2011.

This analysis revealed that learning-related changes in MT showed a trend toward significant correlation with changes in beta ERD in P-SMC ( β = 0.036, p = 0.045; with all conditions included, β = 0.030, p = 0.089; Fig.