Additionally, most of the detected miRNAs, including the selected miR-150-5p and miR-23b-3p, did not reach the conventional significance threshold of adjusted p -values < 0.05, but they showed a trend toward significance with p < 0.05.
Although there was no notable disparity in the levels of HDL‐C between the two groups, the levels of TC and LDL‐C in the SA group showed a trend of increase compared to the NSA group, with certain time points showing significant differences (TC, at the fourth to eighth month, p < 0.05; LDL‐C, at the fourth, fifth, and eighth month, p < 0.05).
Although total motor score and total phonic score showed a trend toward higher scores in the comorbid allergic disease group, no statistical differences were observed between the two groups (all p > 0.05).
After the rTMS treatment, the robotic rTMS group showed a trend-level decrease in the BDI scores (z = − 1.95, p = 0.05), whereas the manual rTMS group did not (z = − 1.48, p = 0.14).
38 , 39 Although the PLR values in the experimental group showed a trend toward being lower than those in the control group, this difference was not statistically significant ( P > .05), which may be related to sample size or the sensitivity of PLR values as an inflammatory marker. 40 Because a pivotal pro-inflammatory cytokine, IL-6, plays a central role in mediating acute-phase responses and inflammation. 19 This study found that IL-6 levels did not significantly increase in the experimental group after treatment, although they significantly increased in the control group ( P value < .05).
Notably, serum Nrf-2 levels in the EtOH group showed a trend toward elevation without significant change ( p > 0.05), whereas GPX4 levels exhibited a trend toward reduction without significant change ( p > 0.05).
With the increase of calcium concentration, soil contents of TC, TN, TP, AK, C:N, C:P, and N:P showed no significant differences ( p >0.05), while soil water-soluble calcium and exchangeable calcium exhibited significant differences and showed a trend of gradually increasing content ( p <0.05).
When stratified by EGFR mutation status, immunotherapy was associated with significantly longer OS in the EGFR wild-type subgroup ( p = 0.004) and showed a trend toward improved OS in the EGFR-mutant subgroup ( p = 0.05) (Supplementary Fig.
Secondary ROIs In making all decisions younger pilots showed a trend for greater activity in the bilateral insula (1.36±0.86) compared to older pilots (0.67±0.49; t (17) = −2.17, p = .050).
As shown in Figure 1 B SERCA2a mRNA levels were significantly higher in diabetic compared to non-diabetic animals and showed a trend towards a further in crease in insulin-treated animals (both p < 0.05 vs control).
Lower household income showed a trend toward association with higher FCR ( P =.05).
In addition, a cluster of frontal electrodes showed a trend ( p < 0.05) toward decreased amplitude and phase advance.
Almost reaching significance was the presence of PETs other than gastrinomas in patients with an MEN1-related death (47% vs 33%, p = 0.058), whereas thyroid disease showed a trend toward higher occurrence in patients with a non-MEN1-related death (0 vs 2.95%, p = 0.050).
Among the 10 platinum agent assays, 2 assays (Oxaliplatin 1, Cisplatin 1) showed a trend of higher AUCs in cell lines with BRCA alterations (unadjusted P < 0.05, adjusted P ≧ 0.05), while no assays showed lower AUCs.
Although analysis of the total tube length per unit area showed a trend toward a longer total tube length in mr‐NPNT‐containing than BSA‐containing control Matrigel, the difference was not significant (Figure 8C and 8E ; n=4, P > 0.05).
Meanwhile, the Anti-CTLA4 group showed a trend of rapid tumor growth after eight days of treatment, indicating that the therapeutic effect of Anti-CTLA4 alone was not satisfactory ( P > 0.05), while the combination treatment with X-PDT or RT could achieve better tumor suppression effect due to the immune system activation by X-PDT.
While ICU LOS in PROSEVA study showed a trend in favour of PP ( P = 0.05) ICU LOS, similar to our study demonstrated no significant difference between two groups (mean difference − 2.23, 95% CI, -5.33-0.87; 4 studies, n = 212).
Similarly, the area under the curve (AUC) of the 3 mg/kg or 10 mg/kg ciclamilast-treated and the 0.1 mg/kg MTX-treated groups also showed a trend toward less paw edema compared with the vehicle-treated rats (each P < 0.05 or 0.01) ( Figure 1 ). 3.2.
Furthermore, the expression of HO-1 protein in the iAs, Mn, and iAs+Mn groups showed a trend similar to that of Nrf2 protein expression (p < 0.05, 0.01, 0.001; see S4 Table , panel B and Fig 4C ).
Pooled analysis of 11 studies involving 818 participants in the prevention cohort showed a trend toward reduction in the need for RRT in the ANP group (OR 0.45; 95% CI 0.21–0.99; P =0.05).
Levene’s test for homogeneity of variances on Day 5 scores showed a trend towards significance but did not reach the conventional threshold ( F (1, 28) = 4.209, P = 0.05).
Still, the post-hoc tests showed a trend that time spent SED relative to LPA and MVPA was larger in DWP than in DWoP (Cohen’s d = 0.36, p = 0.05).
Notably, putrescine levels were significantly higher in the probiotic group at both weeks 4 and 8 ( P < 0.05), whereas glycine levels showed a trend toward increase at week 12 ( P = 0.050), following the probiotic-only phase.
Regarding fibrosis indicators, although PCSK9i use showed a trend toward improvement in Δ APRI (β = −0.021) and Δ FIB-4 (β = −0.19), these associations did not reach statistical significance in the adjusted model ( P > 0.05).
In the airway analysis, the volume increased by 6.2% ( p = 0.327), while the area showed a trend toward improvement (20%; p = 0.050), approaching statistical significance.