Hypocretin ( Hcrt ), also known as orexin, which was detectable only in the NTS in the present data set, was downregulated in SHR versus WKY rats at the hypertension onset and showed a trend toward normalization by 24 wk ( Fig. 6 F ).
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SARS-CoV-2-Δ8 infection showed a trend of increasing IFN signaling (IFNλ3, interferon-stimulated gene [ISG15], and MX1, P values 0.4337, 0.1126, and 0.2285, respectively) as compared to WT at 3 dpi, while reducing IFN-stimulated gene levels (IFNλ3, ISG15, IFIT1, OAS1, and XAF1) at 6 dpi.
Globally, the mortality risk of successive younger birth cohorts also showed a trend of differences among SDI quintiles.
In the present study, the transient group had a higher incidence of adverse events after the first vaccination, whereas the persistent group showed a trend toward a higher incidence of adverse events after the second or third vaccination.
RAI calculations for the stratified groups showed a trend for most subgroups valuing screening start age and risk of dying from breast cancer as the most important attributes.
Co-administration of laminarin and zymosan in the knee joint of C57bl/6 mice showed a trend to a decrease of 99m Tc uptake in the early phase of inflammation in a laminarin-treated knee, compared with an untreated knee, at 4 hours and 1 day after administration, but did not reach statistical significance (Fig. 5b ).
Effect of crop succession on soil enzyme activity Soil urease activity in millets of different cropping years and rotations showed a trend of increasing and then decreasing with the fertility period (Fig. 3 ), the urease activity of the CK treatment continued to increase up to the filling stage, while that of the continuous cropping treatments began to decrease after the flowering stage.
Aligned with the human serum results, the ASAH2 protein expression in 3xTg AD liver showed a trend toward increased levels in the early stage (three-month-old) compared to NonTg (Figure 3A ).
Hypopharyngeal cancer also showed a trend towards risk elevation (RR = 2.15), though it was not statistically significant.
Although the deviations were large, the results showed a trend that choroidal thinning was suppressed as the administration dose increased.
In external validation cohorts, Hcit showed a trend as a risk factor for incident diabetes (HR = 1.05, 95% CI = 0.74–1.48) in MDC.
Tumor size and clinical staging data at the time of diagnosis also showed a trend toward earlier diagnosis; thyroid cancer patients diagnosed during 1993–1998 were diagnosed earlier than those diagnosed during 1979–1992 [ 38 ].
As can be seen from Figure 7 , the COD and turbidity of the trial and control group showed a trend of rapid decline at first, then became stable, and slowly rose at last, indicating that a too long sedimentation time was not conducive to coagulation.
The TFC showed a trend of fluctuating decline, and decreased from 1.70 ± 0.04 mg/mL to 0.82 ± 0.04 mg/mL at 0–10 h, and then increased at 10–14 h.
The analysis of the mean proliferation index (PI) showed a trend for a significant difference between the 45,X and 46,X+der(X)/der(Y) cell lineages; however, there were no intra-individual differences.
In addition to the first signal, a second SNP, rs10181773, showed a trend toward association exclusively in the low sun-exposed population.
The results showed a trend towards a decrease in salivary cortisol levels after both therapies, in most cases with no counterproductive effects or increased stress.
The present study showed a trend toward dorsal surgical therapy.
Even if no significant differences were eventually found in FFGR and FFRS, the CKS curve showed a trend for higher readmission rate, with the curves’ gap more pronounced between 12 and 36 months of follow-up.
We also proved that patients showed a trend toward functional improvement.
While patients who received nutritional supplements alone showed a trend toward enhanced cognition compared to those who received no intervention, the multidomain approach emerged as the most effective.
This study showed a trend toward better outcomes in the TH group than in the normothermia group, without increased systemic complications [ 20 ].
Subgroup analysis by intervention types showed a trend for lower ORR of lung NETs treated with ICI monotherapy (ORR: 2.7%; 0.0–63.7) compared with combinations (p-value: 0.056).
The sxtA4− genotype showed a trend of emerging as the season progressed, in which it was recorded at a higher-than-usual frequency in June (~35% on 23 June 22) and Sept 2022 ( Figure 8 A), during prime bloom season.
Meanwhile, however, distributions of fill factor (FF) values showed a trend that is close to that of PCE distributions.