Evaluation of the specific differences between the time points with the Wilcoxon Signed Rank test showed a trend toward higher levels of galactosylation upon vaccination of the 6 children with the tetanus booster (median at day 0 = 51.3%, day 14 = 64.7% and day 28 = 62.1%; p value = 0.028).
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However, preliminary DL1-DL4 pharmacokinetic data showed a trend for a negative correlation between LPT dose and VNR clearance (see below), warranting the exploration of an immediate higher and approved LPT dose with the VNR dose used in DL3 in order to confirm potential pharmacokinetic interactions and to decide whether full dose anti-HER2 therapy could be maintained in the final combination.
Persons who were in quarantine for a longer duration showed a trend toward higher CES-D scores; however, this difference did not reach statistical significance (mean CES-D of 17.0±14.2 for those in quarantine >10 days versus 11.2±10.1 for those in quarantine <10 days [p = 0.07]).
A cross-sectional study showed a trend for an increasing prevalence of thinness across different ages (7–9 years) in French children [32] , while an Italian study indicated a slight reduction during a short period (from 2004 to 2006) in the thinness prevalence particularly in males, which are data that are in agreement with our findings [30] .
Up until day 9, the treatment-related responses of the zooplankton community in the SAT 33 and CAT 33 treatments, characterised by more or less the same initial peak concentration, were similar, but after that the SAT 33 treatment showed a trend of recovery in contrast to the CAT 33 treatment (Fig. 2 ).
3.2 Reduced expression of the entire h GH / CSH gene cluster in pre-eclamptic placentas In the pregnancies complicated with PE the placental expression profile of the entire h GH / CSH gene cluster showed a trend of reduced expression compared to the controls ( Fig. 1 A–G).
Expression analysis by quantitative PCR (q-PCR) analysis using different skin tissues from embryonic stage E13 to E21 showed a trend of increased expression as the embryo developed ( Fig. 3B&C ).
Although it did not reach statistical significance, knock down DOK-1 showed a trend of increase in BAL inflammation and airway responsiveness, especially in EPO (+) cells and airway responsiveness at 50 mg/ml methacholine challenge, compared to vehicle-challenged mice ( Figure 2 ).
In the adjuvant therapy group, both univariate and multivariate analysis showed no significant difference in prognosis between the anthracyclin-based regimen and 5FU-based regimen, although patients with the former regimen showed a trend-level improvement in prognosis over those with the latter.
Conversely, patients with spontaneous ICH showed a trend towards benefit from platelet transfusion (OR 1.825, 95% CI 0.892 to 3.734).
The remaining proteins studied here showed a trend or were not associated with any specific site of dissemination (see Table 4 ).
Compared to bottle-fed infants, breast-fed infants showed a trend towards shorter sleep times and greater feed times, with fussing times similar to those reported for infants using Bottle B and higher than for those using Bottle A.
The Antioquian sample showed a trend towards higher BMI with increasing number of copies of the previously reported associated allele, although not reaching statistical significance (TT: 26.35, AT:26.74, AA: 26.82; P = 0.14).
Zinc deficiency showed a trend going in the same direction with prevalence decreasing from 77% to 60% from the poorest to the wealthiest category whereas the risk for vitamin A marginal status was in contrast significantly lower in the poorest category 1.
In the other head positions, the effects showed a trend but failed to achieve statistical significance (F (1,38) = 3.069, p = 0.08, for the "head vertical" condition; F (1,38) = 3.721, p = 0.06 for "left-tilt").
In the same light, the combination of craniectomy plus hypothermia applied immediately after surgery showed a trend towards positive impact on stroke severity against craniectomy alone [ 34 ].
In frozen serum samples, the results showed a trend of significantly decreasing SAA, as well as M-SAA concentrations over time.
ACC1 ( P = 0.057) and MTTP ( P = 0.084) showed a trend toward an interaction effect in the multivariate model including fasting and denervation.
Condom use measured via a single, “yes/no” question about “current” use, was not predictive, while consistent condom use, derived from a series of questions enquiring about condom use by each partner type during a specified timeframe, showed a trend toward halving pregnancy risk in the adjusted analysis.
Local accumulations of the cytoskeletal protein neurofilament L in axonal swellings showed a trend towards being more frequent in of KIF5A –/– motor neurons (12.4 ± 5.1 % of cells), in comparison to KIF5A +/– (9.3 ± 1.0 % of cells), and KIF5A +/+ (4.3 ± 4.0 % of cells) motor neurons, but the difference did not reach statistical significance (Fig. 2 ).
In paired samples, SFMCs showed a trend towards higher IL-6 and IL-8 production compared to PBMCs (Table 1 ) Conclusion Increased TLR expression and signaling on PBMC and SFMC from JIA-ERA patients may exacerbate disease by upregulating IL-6, IL-8 and MMP-3 in response to microbial/ endogenous ligands.
In parallel, the SSNRI bupropion showed a trend for improving cognitive performance in schizophrenia but needs to be further evaluated.
Strikingly, HCF quenching upon application of FR light was completely abolished in the presence of nigericin and DTT and showed a trend of an increase in the presence of tentoxin, a specific inhibitor of thylakoid ATPase (Compare Figure 8 ).
According to them [ 13 ] nonsclerosed glomeruli showed a trend of increased volume in older than in young donors group.
Among the four genes, methylation of the RARβ2 gene was significantly associated with smoking and other three genes showed a trend of association.