Similar to a previous post-hoc analysis [ 18 ], the rate of FVC decline of patients in GOLD Stages I + II showed a trend toward being higher than that in GOLD III + IV patients in this substudy, but this did not reach statistical significance.
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Consistent with this animal work, we observed that higher total and monounsaturated fat intakes at the previous eating occasion were weakly but significantly associated with decreased intensity ratings and polyunsaturated fat intake showed a trend in the same direction.
Poor oral hygiene showed a trend to be associated to failure rates.
Surprisingly, microarray analysis found that THBD was downregulated in old ovaries; however, qRT-PCR analysis showed a trend toward upregulation ( Table 3 ).
Additionally, when stimulated with VEGF (20 nM), iMDFECs showed a trend of increased total tube length compared with that of the control MSCs, suggesting that the iMDFECs were responsive to angiogenic growth factor (Fig. 1d ).
There were no significant associations of ghrelin haplotypes with BMI or obesity, although haplotype 4 showed a trend for increased obesity risk after adjustment for age and sex ( Table 3 ).
The anti-VEGF plus PDT group also showed a trend of superior visual outcome, but this was not clinically significant [ 49 ].
Although few of these results were statistically significant because of the considerable reduction of the sample size, the results showed a trend of the risk of developing BC being reduced after FTP (Supporting Table 2 [see online supporting information]).
Force-matching error The RMS error data showed a trend towards greater error during pain, although this did not reach significance.
Protein content of ordered lunch and all food orders of the day combined showed a trend, with orders of patients receiving only a verbal prompt or a verbal prompt and verbal praise containing a larger amount of protein than lunch orders of patients in the control condition.
Circulating CD25 int-high FoxP3 high Tregs of patients showed a trend towards increased expression levels of FoxP3 (Fig. 2a ).
The apical release of TNF-α showed a trend for reduction with the ERK1/2 and p38 MAPK inhibitors, but this failed to reach statistical significance ( Fig. 7F ).
Interestingly, these patients showed a trend towards lower levels of poly-GR inclusions (Fig. 6 a), suggesting differential translation or aggregation of these DPR species in the cerebellum.
Using zero inflated negative binomial models, results of the univariable and multivariable analyses in this subgroup (web appendix 5) showed a trend similar to the larger dataset, but with wider confidence intervals, owing to a reduced sample size.
The seizures did not reoccur, but repeat ammonia levels over the ensuing two days showed a trend upwards, 47 μmol/l and 57 μmol/l, respectively.
While this may skew the homing receptor profile in the pneumonia group toward a systemic rather than local type, it is remarkable that, compared with vaccinees, the homing receptor profile in pneumonia showed a trend toward a more mucosa-oriented type, even though only bacteremic patients had been included.
Our results showed a trend of an increase of tail rattles relative to B6 in the C6-1 sub-subconsomic strain, which has the proximal segment of the C6 region, whereas no behavioral change was observed in the C6-2 strain, which has the distal segment of the C6 region.
Linagliptin 5 mg also showed a trend of nonsignificance to improve indexes of β-cell function, including fasting insulin, disposition index (DI), and homeostasis model assessment (HOMA) of IR. 25 Linagliptin as add-on therapy to one oral antidiabetic drug A 52-week, multicenter, open-label study evaluates the efficacy of linagliptin 5 mg once daily as add-on therapy to one background oral antidiabetic drug (OAD), including biguanide, glinide, glitazone, sulphonylurea (SU), and α-glucosidase inhibitor (A-GI), in 618 Japanese patients with T2DM inadequately controlled.
Furthermore, co-administration of DM with oxycodone showed better effects than oxycodone alone in suppressing the SNL-induced activation of astrocytes and microglia in the dorsal horn of spinal cord and also showed a trend to enhance the effect of oxycodone on decreasing the plasma level of proinflammatory cytokines.
Following 120 min of hypoxia the pharmacological agent showed a trend towards an elevation in cardiomyocytes survival without reaching statistical significance. 2.3.
Consistent with working memory, the first experiment showed faster RTs for CRs compared to baseline, but this was not true for the second experiment that instead showed a trend to the opposite.
For both red cells and white cells, R-BMS showed a trend to report features more relevant to diagnosis than NR-BMS groups, with a statistically significant difference demonstrated for white cell forms ( Fig. 6 a and b).
A kinase previously not linked to breast cancer subtypes, TESK2, also showed a trend for more frequently harboring an HFI SNP (rs17853159) in TNBC compared to ER+cancers (16% vs 3%, P-unadjusted = 0.06).
The VAMPIRE (Vacuum Aspiration Thrombus Removal) trial showed a trend toward lower incidence of no-reflow and a significantly higher rate of myocardial blush grade 3 in patients treated with thrombus aspiration compared with standard primary PCI 11 .
63 However, a comprehensive evaluation of baseline VEGF-A levels in several Phase III trials of colorectal, lung, and renal cancers showed a trend toward an adverse prognostic effect with higher VEGF-A levels but showed no predictive value for treatment with bevacizumab. 64 We eagerly await biomarker analysis from the studies of ramucirumab.