“showed a trend”

In a pilot behavioral experiment, ISRIB showed a trend towards enhancement of spatial memory in the Morris water maze Although we did not have a marker of target engagement in the brain for ISRIB, we decided to proceed with a pilot study to test its effects on learning and memory in nontransgenic mice.

On the other hand, PSD, not HSD, showed a trend of correlation with Maintenance Wakefulness Test score at BL.

We concluded that the addition of thalidomide to the CHOP regimen significantly improved the CRR and showed a trend of improving clinical outcome in patients with DLBCL, especially for patients with Bcl-2 positive and Bcl-6 negative B-cell phenotype, without increased toxicity. thalidomide chop diffuse large B-cell lymphoma pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes p

Interestingly, the placebo group showed a trend towards improvement in their follow up depression scores compared to the baseline in the P→T treatment (Group B) (Table 2 ).

The 12 week timepoint was selected as the primary exploratory endpoint based on similar early phase clinical development studies in diabetic nephropathy ( Pergola et al., 2011 , Ruilope et al., 2014 ) and a previous study in subjects with type 2 diabetes that showed a trend for improved glycemic control at 8 weeks which dissipated thereafter ( Skyler et al., 2015 ).

Of note, mRNA amounts of CHI3L1 were highest on pure Th17 cells and showed a trend to decrease in the other CD161+ subsets, suggesting that it could represent a sort of marker of Th17 lymphocytes.

Interestingly, MGMT methylation showed a trend associated with gender, and methylation is lower in males compared with females (OR = 0.76, 95% CI = 0.56–1.03).

In lower-risk MDS patients with 5q deletion who received lenalidomide treatment, unmutated TP53 status showed a trend to predict the achievement of HI and CyR [ 35 ].

In particular, Actinobacteria (phylum), Actinobacteria, unclassified 4C0d.2 and Betaproteobacteria (class), Actinomycetales, unclassified MLE1.12 and Lactobacillales (order), showed a trend towards increased abundance in Trial subjects compared with Control subjects by paired t-test ( Fig. 1B ).

The study by Flood-Page and colleagues ( 57 ) showed a trend towards reducing severe asthma exacerbations with the higher dose of mepolizumab.

Near-miss events (errors without adverse outcome) showed a trend to be more accurately reported by physicians, with medical error found in 12.1% of physician-reported cases (95% CI = [10–15]) and in 9.1% of those reported by patients (95% CI = [2–24] p=0.79).

A prospective randomized versus a sham coil stimulation (silent sham-coiled + active coiled angled 90°) study, using a H shaped coil, specially designed to reach deep brains structures, stimulating with the inhibitory rTMS protocol described above, showed a trend toward a transient clinical benefit in blepharospasm patients.

An opposite pattern emerged for the left CST, where left CST λ ⊥ displayed a negative linear relationship with LI CV , whereas right CST λ ⊥ showed a trend towards a positive linear relation with LI CV .

Among ADA users, the 1-year IRR of TB showed a trend of elevation from 2008 to 2010, followed by a trend of decline.

At 2 h after treatment, sumatriptan showed a trend towards efficacy and 4 h after treatment the effect was highly significant.

Baseline activity showed a trend to higher values after muscle fatigue, as well as reduction through perturbation trials.

Second, a comparison of the number of toys given showed a trend toward children from School A giving more toys than children from School B, showing that children from the middle SES neighborhood gave away more toys than children from the more deprived neighborhood.

Saplings on sandy soil showed a trend toward a larger change in δ 13 C suggesting higher stress than in loamy soil.

Urine Urinary cGMP levels showed a trend toward an increase by Day 7 and were significantly increased by Day 21; urinary ANP levels significantly increased by the end of each treatment period (Table 2 ).

This result was confirmed by a Cochrane meta-analysis, 124 which showed a trend toward increased risk of secondary malignancies in patients receiving ASCT.

The absorption coefficient data of seven DNA samples (293 T, M-293T, PC3, A431, A549, MCF-7, and SNU-1) showed a trend of ice in the THz range but indicated bumps around 1.6 THz.

Those Mecp2 −/y mice receiving low or high Trolox doses, showed a trend towards higher glucose levels and they did no longer differ significantly from PBS-treated or Trolox-receiving WTs (Figure 2C ).

They included 7 RCTs and showed a trend towards an association between PPIs and respiratory infections, although it failed to reach statistical significance (OR 1.42, 95% CI 0.86–2.35; P = 0.17).

However, HLA-A2 + patients with high preexisting or vaccine-induced immunity to E75, showed a trend for shorter PFS.

Background The CvLPRIT study showed a trend for improved clinical outcomes in the complete revascularisation (CR) group in those treated with an immediate, as opposed to staged in-hospital approach in patients with multivessel coronary disease undergoing primary percutaneous intervention (PPCI).