“showed a trend”

In contrast, transcriptional activity at H3K4me3/gain H3K27me3 bivalently marked loci did not significantly change between time points, but instead showed a trend toward a steadily reduced median expression which was maintained upon reoxygenation (Additional file 1 : Fig.

Ank KI/KI mice showed a trend but no statistical significance in the increase of intact FGF23 but a significant increase in the inactive C-terminal fragment of FGF23 suggesting that more FGF23 is processed in Ank KI/KI mice.

Conclusion Results of this subgroup analysis showed a trend favoring ramucirumab+docetaxel for median OS, PFS, and improved ORR in East Asian patients, consistent with ITT population results.

Cotreatment with HN showed a trend for an increase in cellular GSH vs TM group but it did not reach statistical significance.

Interestingly, the recently published Pan Canadian Rash trial ( 16 ) on the use of minocycline in the management of skin rash caused by erlotinib in lung cancer showed a trend toward improved survival associated with the early use of minocycline (7.6 and 8 months in prophylactic and reactive use) versus if used only when severe rash appears (6 months).

Factors associated with loss to follow-up On bivariate analysis, ART status, age and patient volume per provider showed a trend towards being predictive of loss to follow-up, and these factors remained predictive on multivariable analysis.

gingivalis showed a trend towards decreased bone density relative to manus from unbrushed control mice, but once arthritis was triggered both groups demonstrated an enhanced bone loss that resulted in destruction of the form and function of the bones analyzed.

As shown in Figure 3 , the IRBP KO animals also showed a trend for longer axial length from P8 onward using the LED non-contact micrometer that became statistically significant at P10 (Appendix 1, panels 3B and 3C).

However, while the annual colony counts of chinstrap and Adélie penguins showed a trend consistent in direction with the results from all-island surveys, the magnitude of estimated population change was markedly different between colony wide and all island counts.

Two imputed SNPs in CDH4 and KRT8P35 showed a trend in interaction with gemcitabine treatment.

Nitrate/nitrite levels in hypergravity-exposed hearts Cardiac nitrate/nitrite levels showed a trend similar to that of eNOS expression and activity (Figure 2B ).

Treatment of Aβ42 alone showed a trend of increase in the basal level of NF-κB activity in BMMs at 0.5, 1, 5, and 10 μM ( Figure 2 A).

The experimental measurements of the corresponding H221L mutation in mouse Kir2.1 channels proved our hypothesis, and the results showed a trend that was similar to that for the mutation from Leu to Ile, which led to faster inhibition dynamics (Fig. 8a, b ) and slower activation dynamics (Fig. 8c, d ).

However, we believe this is unlikely, because both quantitative PCR (qPCR) data from the present soil samples ( 16 ) and phospholipid fatty acid (PLFA) analysis ( 22 ) from the 20-year site showed a trend toward reduced fungal abundance and increased or unaffected bacterial abundance with warming.

While beauvericin showed a trend towards a reduction after the acid treatments, monilformin concentrations were not affected by the treatments.

glabrata peaked in 2004 (30.0%) and in 2007 (46.9%), respectively, then subsided, both showed a trend toward increasing after 2012 ( Fig 2 ).

B2 showed a trend in atherosclerotic lesion area reduction in both 4 mg/kg and T3–15 mg/kg treatment groups but did not reach statistical significance (mean±SEM: 525±3.6% vs. 69.2±14.0% p =1.0 and 43.6±12.0% vs. 69.2±14.0% p =1.15 respectively).

ERα66 was consistent across all passages in vehicle control samples, but showed a trend towards decreased protein expression following EE treatment ( Fig. 3C ).

Treatment participants showed a trend toward greater improvement in emotional well-being compared to control participants.

Although it was shown that spheroids of different donor samples produce different amounts of GAGs and the ratio of bound to released GAG (per spheroid) showed a trend of a positive correlation with tissue regeneration capacity of spheroids, this could not be confirmed by Spearman’s correlation test that only showed a trend and not a statistical significant correlation.

Results for the other subgroups generally showed a trend in favor of galantamine, regardless of age, MMSE values, or DAD values at baseline (Fig. 1 ).

The gastrocnemius and quadriceps muscles from AAV1- Sirt1 -treated mice showed a trend to express higher levels of the oxidative fiber marker MyHC I when compared with AAV1-Null mice, whereas no differences were observed in the levels of MyHC IIa , MyHC IIb , and MyHC IIx ( Figure 2a , b ).

The results showed a trend toward decreased LPS induction of the tested genes by M3G.

Most previous studies using Aprotinin injection in the management of Achilles tendinopathy showed a trend towards improved clinical results [ 97 , 98 ].

In contrast to UFH, LMWH showed a trend toward stronger inhibition of thrombin-induced activation compared to the activation caused by both virus strains, with inhibition of thrombin activation starting at 0.1 μg/mL LMWH and being almost complete at 0.5 μg/mL (Figure 2 ).