Barely Significant
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“showed a trend”

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In the literature

To date, of the 5 military studies with MTBI evaluated in the current review, the influence of APOE-ε4 status on outcome after MTBI remains unclear: one study of 458 active-duty subjects showed a trend of increased prior concussions in ε4-carriers, one study of 87 veterans showed interaction between ε4, PTSD and DNA methylation, one study of 120 veterans showed interactions between ε4 status and diagnosis of TBI and PTSD, one study of 53 active-duty subjects showed a relationship between job status and memory performance associated with ε4-carriers, and one study on cortical thickness was negative.
The remaining 10 proteins showed a trend of up-regulation in both genotypes, but the expression level of ‘Yayu889’ was significantly higher than that in ‘Zhenghong532’ at all four time points, including two CML proteins, two LRR-RLK proteins, RING-H2 finger protein ATL2A, nematode resistance protein-like HSPRO2, putative serine/threonine-protein kinase-like protein CCR3, protein LYK5, MAP kinase kinase (MKK), and glutathione- S -transferase (GST).