In fact, D‐dimer showed a trend towards lower plasma concentrations in children and young adults randomized to weekends off efavirenz‐based ART in one of these studies 50 , which was unexpected, but similar to our findings of lower D‐dimer in sub optimally adherent participants in START.
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Conclusion In this study, we showed a trend for lower connectivity between genes in the gene coexpression networks of colorectal adenoma and carcinoma as well as aldosterone producing adenoma and uterine leiomyoma.
The SPECT results showed a trend in favor of the ASC-treated patients in terms of the differences between ASCs and placebo group for change from baseline in percent LV with stress defect.
However, LP2 showed a trend towards agglomeration and formation of fragile spheres and dust particles during the process.
In DM1, each 3a allele showed a trend towards reduced somatic expansion and delayed onset but was significantly associated with both measures in meta-analysis of Huntington’s disease and DM1.
B-cell depletion using an anti-CD20 antibody in a small cohort showed a trend in reducing inflammation, although nonsignificant 42 .
β-actin mRNA also showed a trend of decrease on Fmr1-KO polysomes which was not statistically significant (Fig. 4d ).
Although our results showed a trend of higher percentages of Th1Th17 CM lymphocytes at baseline in DMF patients who develop at least one relapse during the first 12 months of follow-up, our study presents an important limitation in the number of DMF patients who had relapses.
While the cerebrum and cerebellum showed a trend toward decreased GBA activity, it was not significant ( Fig 3C and 3D ).
Asap1 GT /GT cultures showed a trend towards increased Alcian Blue staining compared to wild-type controls ( Fig 6A ).
Treatment with any of the agents as a monotherapy showed a trend toward increased survival time (median survival of 62 and 59.5 days for mAb or A2ARi, respectively), whereas the combination caused a significant increase in median survival time (69 days) over both immunoglobulin G (IgG) + Mock (58 days) and any of the treatments alone ( Fig. 6J ), supporting a favorable additive effect on survival by blocking different nodes of the adenosine signaling pathway.
In addition, diastolic function showed a trend towards improvement, although LAP did not reach statistical significance.
Sensitivity analyses with longer follow-up period showed a trend towards lower overall mortality associated with AAD usage.
The aCRT algorithm showed a trend toward better performance in terms of clinical outcomes and electromechanical remodeling compared to the conventional optimization methods requiring extra time and cost for cumbersome measurements.
Furthermore, patients with high TMB showed a trend towards prolonged survival (Fig. 3 a-d) (Table 2 ).
The analysis procedure was as follows: (a) The program obtained a gene across the max‐log ( p ‐value) from all SNPs within a 20‐kb interval; (b) Genes were ranked via the p ‐value for the association test; (c) The list of ranked genes was used to calculate enrichment scores (ES) of the pathways, and the ES showed a trend in which the genes in the pathways were located from the top of the list of entire ranked genes; (d) A phenotype label permutation and normalization were performed to obtain the ES distribution, and correct the gene and gene set variations; (e) False discovery rate (FDR) was performed for multiple tests based on the ES distributions generated by permutation tests. 2.6 Network and network clustering analyses of genes associated with insomnia A pathway‐based analysis can identify genes and pathways that are associated with insomnia.
In addition, the ratio of Bcl-2 to Bax was significantly decreased in the Ad-RNF10 group (P<0.05) and showed a trend towards a slight increase in the group infected with Ad-shRNF10, but there was no significant difference (P>0.05) ( Fig. 2A, C and D ).
Girls and children from families with less than one acre of land showed a trend toward being associated with VAD [ Table 1 ].
In addition, the high-trait-anxiety group showed a trend to display toward higher levels of state anxiety than the low-trait-anxiety group.
The result of self-care just showed a trend of increase after the nurse-led care [37] . 3.5.3.
Also, thirteen patients of the preferred group (68%) did not show a significant change in post-intervention depression, although three could not recover due to floor effects and eight showed a trend of (non-significant) improvement in depression.
Male aviary chicks showed a trend toward faster body mass gain than females, which was however not found to be statistically significant ( Table 2 ).
All of the main lactate producers showed a trend of increased relative abundance.
In the previous studies based on Japanese populations, 71–85% of BW reduction achieved with SGLT2 inhibitors resulted from fat loss as assessed with BIA 14 , 15 , 16 , 17 , and the reduction rates seemed to be dependent on the “treatment period.” The studies 16 , 17 showed a trend toward a greater reduction rate at 6 or 12 months than that at 3 months.
As indicated in Figure 4 A–E and Table 3 , the AutoDock scores of compounds 3 and 5 showed a trend similar to their IC 50 values in vitro.