“showed a trend”

A randomized proof-of-concept study indicated that secukinumab reduced lesion activity in MS patients and showed a trend toward reduced relapse rates [ 31 ].

Interestingly, both RANTES and MCP-1 levels showed a trend toward higher inflammatory cytokine values in low respect to high pressure group, but they were not significant.

The staining results showed a trend of increasing intensity of ChREBP with HCC malignant progression as defined by histopathological diagnosis (Fig. 1 b).

While treatment with emollient therapy showed a trend toward increased weight gain, especially in the younger patients, this effect did not reach statistical significance, and time to clinical recovery from the acute phase of illness was not measurably impacted.

Patients’ time of death was significantly associated with outcomes negative affect (alive beta: .066; deceased >3 months ago beta: –.289; time of death unknown beta: .086; deceased ⩽3 months ago as reference category), satisfaction with life (alive beta: –1.38; deceased >3 months ago beta: .984; time of death unknown beta: –1.70), subjective distress (alive beta: .424; deceased >3 months ago beta: –1.13; time of death unknown beta: .360) and psychological impairment (alive beta: .615; deceased >3 months ago beta: .456; time of death unknown beta: 1.83); patients’ time of death showed a trend to be associated with anxiety (alive beta: .011; deceased >3 months ago beta: –1.55; time of death unknown beta: .982).

In the esophageal cohort, 23 patients were enrolled, and a 6 gene IFNγ signature was tested, and showed a trend toward predicting for response to ICI ( 34 ).

Primary ACC tumors (n=107) in comparison to metastases (n=23) showed a trend of higher median number of CD3 + − (8.5 vs. 5.4 per HPF) as well as CD3 + CD4 + − and CD3 + CD8 + T cells ( figure 2A–C , online supplementary table S2 ).

Moreover, levels of TGF-β1 and amphiregulin in lung tissue showed a trend towards an increase in GP-SLIT treatment in the presence of VitD3 (Fig. 6E ).

The 200-μl group also had similar miR-451a concentration as in 50-μl and 100-μl, but for miR-23a-3p and miR-103a-3p it showed a trend towards normalization.

The possible explanation is that the air pollution level in Shanghai of 2013–2015 showed a trend of rising, but it has been persistently declining in Lanzhou since 2013 [ 36 ].

Mice receiving S29434 also showed a trend of reduced Kv2.1 oligomerization ( Fig. 5 h ), albeit this was predictably less effective than local viral infection.

When hormone levels in male and female subjects were related to the respective titer increases/decreases, testosterone concentrations in males showed a trend toward negative correlation with titer increases from d0 to d28, and positive correlation with baseline NT titers and decline rates.

The microvascular permeability in WT → Bam32 −/− mice showed a trend of increase compared to WT → WT mice, which shared the same WT neutrophils but had different genotypes of endothelial background, and this reached significance at 15 min after superfusion with WKYMVm ( Figure 2B ).

Longitudinal samples collected over time of children with CF showed a trend toward less stability in the microbial composition of older children, possibly related to increased exacerbations and infection with traditional CF pathogens.

In follow‐up post‐hoc tests, all active intensities showed a trend of decreased CBF in the targeted left M1 area (Figure 3 h).

Similarly, flowers protected from UV showed a trend of reduced UV-B reflectance, but the difference was not significant ( N = 50, V = 812, P = 0.09; Fig. 2 ).

Furthermore, determination of the proliferation and cell death patterns showed no significant differences between control and mutant limb mesoderm, although mutant limbs showed a trend to lower proliferation ( n = 3 WT and 5 DKOs; fig.

NT-proBNP also showed a trend almost parallel to that of CTR ( Fig. 2a ).

Although Tukey post hoc tests did not find significant differences, the data pattern still showed a trend for a “wrong-hand effect”: Mixed left-handers tended to have higher accuracy for right-hand stimuli ( M = 91% ± 2%) than for left-hand stimuli ( M = 86% ± 2%); mixed right-handers tended to have higher accuracy for left-hand stimuli ( M = 92% ± 2%) than for right-hand stimuli ( M = 83% ± 6%).

Western blot and immunohistochemical staining for PCNA in representative liver sections of Mdr2-/- mice with or without cholesterol supplementation showed a trend similar to that for wild-type mice (Figures 6(c) and 6(d) ).

With increasing catalyst dose, the oil content of oily sludge in the ozone-catalyzed oxidation groups both showed a trend of first decreasing and then increasing.

Urinary Burden The mean 24-hour urine volume on treatment showed a trend to increase with tolvaptan dose, with values ranging from approximately 4750 ml for tolvaptan MR 20 mg to 7400 ml for tolvaptan MR 120 mg and IR 90+30 mg ( Figure 5 a).

The pheta1 heterozygous ( pheta1 +/− ) and homozygous ( pheta1 −/− ) animals showed a trend of reduced tracer uptake, compared to the WT control animals, but the difference did not reach statistical significance ( Fig. 3 B) (Chi-square test; sample sizes are shown in the figure).

In female participants, the associations between energy intake or physical activity and sarcopenia after adjusting for confounding factors showed a trend similar to that of males ( Table 3 ).

During wet periods, the mean soil moisture in the P1 site profiles showed a trend of first increasing and then decreasing with depth, with values of 27.3%, 41.2%, 32.5%, 33.1%, and 31.0% for the 0–10, 10–20, 20–30, 30–40, and 40–50 cm depths, respectively.