The BV/TV ratio showed a trend similar to BMD ( Figure 6B and C ).
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Again, arc-like and needle-like anhydrous cholesterol crystals showed a trend towards smaller AUC (43.1 ± 9.2 vs 32.9 ± 10.1 in bile without and with the added stones, respectively).
Conversely, the long-chain metabolite α-13′-OH and its isomer M3 showed a trend toward a decrease after treatment; the opposite was found in the placebo group that showed increased levels of α-13′-COOH at the end of the study (Table 3 ).
Only the levels of tph2 were significantly reduced, while the two other isoforms showed a trend towards reduction.
Examination of protein extracts from the hearts of mixed background mice after TAC revealed a trend towards increased expression of many ER stress-activated proteins and chaperones such as binding immunoglobulin protein (BiP), calreticulin, hypoxia up-regulated protein 1 (Hyou1), arginine-rich, mutated in early-stage tumors (ARMET), protein disulfide isomerase (PDI), stromal cell derived factor 2 like 1 (Sdf2l1), as previously described by us 2 , and gene-deleted mice lacking Atf6 or Atf6b showed a trend towards reduced expression of some of these ER stress responsive proteins (Fig. 1e ).
Mutation of the residues, which could be phosphorylated in the SDSDY sequence, showed a trend toward increased responses reaching statistical significance in response to CD3 mAb (shown for 0·25 μg/ml) when all three were mutated (Fig. 2 b, ADADF).
The results showed a trend towards a negative correlation between the initial screw angle and the rate of correction with a p-value of 0.2 ( Fig. 1 ).
Subcutaneous administration of acetazolamide showed a trend towards a reduction in ICP at clinical (19% reduction) and high doses (20% reduction); however, it was not significantly different compared to the 2% and 4% NaCl controls respectively ( Figure 1(c) and ( d ), and Table 2 ).
The species showed a trend toward occupying the best available areas ( Table 3 ).
Although they did not reach significance, our sensitivity analyses also showed a trend towards an inverse association between serum PFNA concentrations and caries prevalence.
Nevertheless, corneal curvature parameters would not remain statistically significant after multiple testing correction but showed a trend to significance.
Runx2 expression also showed a trend towards reduced expression, although this was not statistically significant.
They also showed a trend toward lower WM volume as compared to controls.
This approach was not only well tolerated, and but clinical response showed a trend toward improved survival in melanoma patients who received a combination of lymphokine activated killer cells with IL-2 ( 5 ).
For the procedural task, accuracy was significantly decreased following daytime wakefulness, showed a trend to increase with a daytime nap, and significantly increased across full‐night sleep.
84 In this study, patients with AN showed a trend towards a lower global methylation compared with patients with BN, and no difference was found between patients with BN and controls.
The effect mediated by the biAb showed a trend of being more potent than the bivalent anti-CD19 mAb (88% vs 66% reduction, respectively, of BCR-mediated B-cell proliferation).
The majority of enriched RISC-bound genes showed a trend to downregulation in the whole cell upon infection, which would be consistent with a reduction of transcriptional levels mediated by miRNAs.
The present study showed a trend of increasing soil pH and ρ with the soil depth in each age group (Fig. 3 ), but SOC exhibited the opposite trend, as low soil pH and ρ are more favorable to an accumulation of SOC 27 .
After stimulation with K562 or 772.221 target cell lines, infant lamina propria-derived NK cells showed a trend towards enhanced degranulation compared to adult NK cells (Supplementary Fig. 5 ).
Ang-(1-7) treatment showed a trend to enhance perfusion compared to the control group, however, comparison of AUC values indicated that differences were not significant when compared to the vehicle group (P > 0.05).
Additionally, the hepatocytes exposed to ethanol showed a trend to increased triglyceride content, especially in the WT ( Fig. 4 G).
The level of A-aDO2, RI, Qs/Qt and MMP-9 in the serum of the patients of the two groups showed a trend of first increase and then decrease, but the level of A-aDO2, Qs/Qt and MMP-9 in propofol group was significantly lower than that in sevoflurane group.
Similarly, acyl-CoA synthetase 6-deficient mice, which have significantly lower levels of DHA and higher levels of ARA in the brain, showed a trend toward reduced rotarod performance at 12 months of age ( Fernandez et al., 2018 ).
In addition, hydroxysteroid 11-beta dehydrogenase 2 (Hsd11b2) and placental lactogen II (Prl3b1) showed a trend toward reduced expression in PR neg CD11c placentas, but did not reach levels of significance.