For the prespecified subgroup analyses, margetuximab plus chemotherapy showed a trend towards greater benefit in prolonging PFS than trastuzumab plus chemotherapy in most of the subgroups ( Figure 4 ).
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miltiorrhiza roots after applying pathogenic fungi showed a trend of first increasing and then decreasing, and the JA content of A-G1 was always higher than that of D-G1 without AM fungi.
Factors Associated With Diabetic Neuropathy in the Study Cohort (See Figure 2 ) The scatter plot with linear regression showed a trend of milder disease severity and shorter diabetes duration in SFN compared to LFN (though not statistically significant).
The content of oleic acid in MUFA was the highest (13.13 % to 20.55 %), which showed a trend of first increasing and then decreasing during fermentation.
In the phase III trial CLEOPATRA, the combination with pertuzumab delayed the median time to development of CNS metastases at the first site of disease progression ( 84 ); in the PHEREXA study, the addition of pertuzumab to trastuzumab and capecitabine showed a trend in PFS benefit ( 85 ); in a single-arm, prospective, phase II study, however, patients with HER2-positive metastatic breast cancer with BMs and CNS progression despite prior radiotherapy received pertuzumab plus high-dose trastuzumab (6 mg/kg weekly), and the CNS-ORR was only 11%, showing a non-significant result ( 67 ).
However, the proportion of acetate showed a trend toward increasing with age, potentially due to variations in dry matter intake (DMI).
The subgroup analysis of Osteoarthritis demonstrated a significant worsening of the opioid therapy compared to placebo ( p = .048), while the Low Back Pain subgroup showed a trend towards an advantage in the opioid group, although it did not reach statistical significance ( p = .052).
The qRT-PCR analysis showed that the relative expression levels of the seven CtWRKY genes were significantly different within 3 h of drought treatment and 48 h of rewatering, and the overall expression pattern showed a trend of first increasing and then decreasing, indicating that these genes may play an important role in the drought stress response.
Our results showed a trend of the pro‐inflammatory cytokine levels being lower in Hispanics as compared to Caucasians, which supports our hypothesis.
Patients who had preoperative plus postoperative radiotherapy showed a trend toward superior local control.
Results of InVEST model As shown in Supplementary Table S8 , the cropland area first decreased in 2002, and then showed a trend of continuous increase, the forest area continued to increase, the shrub area fluctuated, the grassland area continued to decrease, and the water and impervious area increased.
Results showed a trend for high MTA1 expression in primary tumors with muscle/vascular invasion, whereas a lower MTA1 expression was associated in those tumors with only lamina propria invasion ( Figure 5B ).
(2019) showed a trend toward higher MEMR thresholds (measured with a 226 Hz probe) for controls compared with participants reporting tinnitus, indicating weaker MEMR magnitude.
G6PC showed a trend of reduction in male SA/SA liver ( Fig. 6G ), but no changes were seen in young male and female SA/SA liver (Fig.
For the other-oriented Justice Sensitivity Index (JSI), acute lorazepam administration showed a trend toward reducing overall other-oriented JSI scores, although this effect did not reach statistical significance [t(80) = -1.943, p = 0.056].
The latter showed a trend of increasing over time.
As monitoring continued (periods 85–120), the displacement gradually showed a trend of faster increase.
The level of hybrid type glycans in plasma associated with the occurrence of cirrhosis and showed a trend towards increased levels with flaring AIH.
In a differential reinforcement of low-rate behavior study conducted with monkeys, RO5203648 showed a trend toward an increased number of reinforcers obtained, which also led to a significant prolongation of the inter-response time and a reduction in the response rate, effects similar to those of antidepressants ( Revel et al., 2012 ; O'Donnell et al., 2005 ).
In pre-menopausal women, FFM, MM and RF muscle thickness increased significantly, while VL showed a trend.
The AIDSVAX B/E only group showed a trend towards greater fold decline compared to the ALVAC-HIV/AIDSVAX B/E group ( Fig 2E ), indicating that ALVAC-HIV may drive the longevity of V1V2 IgG responses.
They found subgroup involving female showed a trend toward a higher percentage with a complete response.
Although the combined effect of the Karnofsky Index and COVID-19 severity on survival showed a trend toward association, it did not reach statistical significance.
5 A-B, the expression levels of the mitochondrial ETC subunits I, II, and IV showed a trend toward decrease, while the ETC subunits III and V levels remained unchanged.
In this study, the expression of the NPL gene showed a trend of first increasing and then decreasing during macrophage differentiation, while the GALNT12 gene was expressed in tumor samples during the third stage of macrophage differentiation.