Within the first hours of treatment, trastuzumab alone slightly reduced cell migration, whereas pertuzumab showed a trend toward a reduction ( Figure 4A ).
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In line with these findings, NRF2 target genes showed a trend towards reduced expression in K. pneumoniae infected cells, when treated with the ROS-scavenger NAC.
In this study, the CAT activity in the mycelia of heat-resistant strain and heat-sensitive strain showed a trend of first increasing and then decreasing with the increase of high temperature treatment time ( Fig. 5. ).
Although showing no significant difference in brain clearance compared to the other monomeric Aβ species, the C-terminally truncated Aβ1-34 consistently showed a trend for a higher brain efflux.
In Figure 9 , the overall food ecological security index showed a trend of first decline and then rise from 2015 to 2010.
As the particle size of wheat bran flour decreased, the bread hardness showed a trend of firstly decreasing and then increasing.
One immunoglobulin dose-comparative study (400 mg/kg daily given for 3 days versus, for 6 days) showed a trend for greater benefit in the prolonged treatment course in terms of median time taken to be able to walk with aid, but this result did not reach statistical significance [ 53 ].
COVID-19 patients with vaccination showed a trend of lower incidence of severe COVID-19 when compared to unvaccinated groups (3/67 (4.5%, 95% CI 0.9–12.5%) vs. 11/92 (12.0%, 95% CI 6.1–20.4%), odds ratio (OR) 0.35, 95% CI 0.09–1.29, p = 0.10); however, the association did not reach statistical significance.
The pre- and post-tests were administered 10 weeks apart and the results showed a trend toward a change in approach to a cooperative style of conflict management, however the difference was not statistically significant [ 19 ].
As the amount of the corncob increased, the reduced iron grade and recovery ratio showed a trend of first increasing and then decreasing.
Indeed, regarding the neuroimaging data, several regions showed a trend for perfusion differences such as the insula and the medial orbitofrontal cortex, which may have reached significance if more participant scans were available.
The relative beam walk performance determined by average time to cross a beam during the test period compared to the initial pretreatment average time to cross the beam (seconds) showed a trend of improvement after 3 months of treatment and at increased dosage, although no significant differences were witnessed between FA (vehicle)- and DMF–Resv-treated mice ( Figure 5B ).
Cohort C showed a trend toward a longer survival time compared to cohort B, but the difference was not significant.
The generated charge (integration of the current profiles) showed a trend toward increasing K uptake ( Figure S11 ).
Another interesting observation is that patients assigned as TIL‐low by KM grading but TIL‐high by DeepTILs showed a trend toward better PFS compared to TIL‐low subgroups by both approaches.
Expression of miR-223-3p in each group was determined through qPCR assay, then it turned out that that expression in model group was notably higher than normal group, the miR-223-3p expression in HF-EA group was significantly lower than the one of model, besides that, when it was compared with the anti-miRNA group, the miR-223-3p expression in HF-EA+anti-miRNA group showed a trend of greatly decline.
The following measures showed a trend towards worsening function with increasing age: ambulation time, gait cycle, number of steps, and gait velocity (eFigure 1, links.lww.com/WNL/B946 ).
Dengue fever mainly occurs in southern provinces in China and its epidemic showed a trend of high incidence in 2019.
In regard to the efficacy of sequential treatment with TFTD and regorafenib administered in the forward or reverse sequence, it is generally considered that there are no differences in the conventional parameters of efficacy, whichever of the two agents is used first [ 9 – 12 ], while some reports showed that patients who received TFTD after regorafenib treatment showed a trend towards a longer PFS than those who received it prior to regorafenib [ 24 ].
The backtracking found that if the value path of the average salary growth rate showed a trend of rising first and then falling, the final reserve status would be “worse;” if it showed a trend of first falling and then rising, the final reserve status would be “better.” According to the above research conclusions, in order to actively respond to the aging population and consolidate the fund reserves of basic pension insurance, the following inspirations can be obtained.
Although this variant is classified as one of the C1INH benign variants ( https://www.ncbi.nlm.nih.gov/clinvar/variation/254786/ ) and yielded conflicting results with age-related macular degeneration ( 35 ), interestingly, it showed a trend of association with susceptibility to staphylococcal aureus colonization of the nose ( 36 ).
The body weight of mice in the oseltamivir, LNT-L, LNT-M and LNT-H groups showed a trend of first decreasing and then increasing.
Although no statistically significant difference ( P = 0.94) in mortality data was observed between MCAO/r and iTBS groups at the end of experiment, iTBS treatment showed a trend of delaying the death of cerebral I/R injury mice.
Levels of macrophage isg15 expression showed a trend of first increasing and then decreasing (Fig. 4 B).
Moreover, the heatmap plot showed that a part of genes in the normal, model and didymin group showed a trend: down, up, and down; the other part showed an opposite trend ( Figure 5B ).