Comparison of PedsQLTM scores between baseline and 12‐weeks posttreatment showed a trend toward improvement on the physical health summary domain of the generic module (median 46.9, interquartile range [IQR] 42.2–60.9 to median 71.9, IQR 51.6–87.5) (Figure 3 ; Supporting Table 5 ).
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Once again, whereas both lixivaptan and R568 monotherapy showed a trend toward reduction of PKA activity, only the combined lixivaptan and R568 treatment statistically significantly reduced PKA activity (65.3% vs.
In allergic participants, BI 705564 treatment showed a trend in wheal size reduction in a skin prick test and complete inhibition of basophil activation.
Median error per provider for the overall recommended procedures showed a trend towards a lower number of errors after exposure to a unique BL course (ie, FFL + e‐learning) than to a traditional FFL course.
When evaluating subjects who completed the 24‐week study period, those in the HDF study arm ( N = 12) showed stable mean weekly dose of ESA over time (baseline: 99 ± 74 IU/kg, week 12: 113 ± 75 IU/kg, week 24: 102 ± 74 IU/kg) while the HDx study arm subjects ( N = 19) showed a trend toward a decrease in weekly ESA dose from week 8 (baseline: 106 ± 87 IU/kg, week 12: 98 ± 102 IU/kg, week 24: 77 ± 103 IU/kg) (Figure 2a ).
Although no significant differences were evident between plant genotypes under the same P conditions, phytase activity in SL‐depleted plants showed a trend to overall higher values than in the wild‐type. 3.4.
Also as shown in Table 1 , the placebo groups had no significant improvement in metabolic parameters, although the BW‐loss group showed a trend towards improvement.
Higher neonatal WMI volume showed a trend towards lower motor scores at 18 months, although not significantly.
Besides, the other three unfavorable risk factors (age >60 years, stage II and elevated LDH) also showed a trend for the distinction of survival.
In our hands, samples from old people or from ET or AD patients showed increased expression of Plin2, but not of Plin5, whereas Plin3 showed a trend to increase as well, especially in frontal cortex and cerebellum, however, without reaching statistical significance.
As a negative control, Fer-1 showed a trend to attenuate the production of lipid peroxidation, and the administration of Fer-1 significantly decreased RT induced lipid peroxidation ( Figure 2g–l ).
Trends were similar to VG results, whereby both AAVs showed similar PAH mRNA levels at the 5 × 10 11 VG/kg dose, but Anc80‐coPAH showed a trend for slightly better transcription than Anc80‐int‐coPAH at the 5 × 10 12 VG/kg dose.
Rats subjected to chronic mild stress showed a trend towards a nonsignificant decrease of mean diffusivity in the bilateral cingulum (Kumar et al., 2014 ).
Though not statistically significant, the level of rScO 2 , pain score, and duration of painful expression in the experimental group showed a trend to return to baseline faster than in the control group, implying the potential soothing effect of white noise in neonates with procedural pain.
While our data showed a trend supporting this conjecture, it was not statistically significant due to the small numbers involved.
Supplementation of GEG to the diet reduced the duration of audible vocalizations in SNL rats significantly, while the other outcome measures showed a trend of inhibition by GEG.
Although the number of patients enrolled in this study was limited, 1‐year follow‐up results showed a trend that patients with isolated central posterior leaflet prolapse and multisegment prolapse but dominated by central segment had more stable MR improvement, which was consistent with other reports. 15 , 16 Four patients had recurrence of moderate or more MR during 1‐year follow‐up.
The HFpEF group also had a significantly higher Charlson Comorbidity Index and showed a trend towards greater frailty (although this was not statistically significant).
Astrocytes showed a trend towards an increased percentage of SRR expressing cells and mean fluorescent intensity at 3 dpi that became significant by 7 dpi.
Moreover, IL2RA (CD25) showed a trend of upregulation in dengue disease (Fig. 1c ).
53 The present study showed a trend towards an increased IPA rate in patients with COPD compared with patients without COPD, although the difference did not reach statistical significance.
Zone 2 VII disease also showed a trend toward increased recurrence risk, but this did not reach statistical significance ( p = 0.158).
The TREM2 R47H/+ femurs also showed a trend toward decreased tissue mineral density (TMD) (Fig. 3 C ) of the cortical bone compared to WT littermates but have similar mechanical and estimated material properties of the femur at 20 months of age by three‐point bending compared to WT mice (Fig. 3 C ).
Overall, the GUHS adolescents showed a trend towards less subcutaneous adipose tissue measured on ultrasound, and an increase in visceral and preperitoneal adipose tissue compared to the Raine Study adolescents.
Although the western blot analysis showed a trend toward increased phosphorylation of these proteins, the quantified values of the protein bands showed no significant differences.