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“showed a trend”

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When evaluating subjects who completed the 24‐week study period, those in the HDF study arm ( N = 12) showed stable mean weekly dose of ESA over time (baseline: 99 ± 74 IU/kg, week 12: 113 ± 75 IU/kg, week 24: 102 ± 74 IU/kg) while the HDx study arm subjects ( N = 19) showed a trend toward a decrease in weekly ESA dose from week 8 (baseline: 106 ± 87 IU/kg, week 12: 98 ± 102 IU/kg, week 24: 77 ± 103 IU/kg) (Figure 2a ).
Although the number of patients enrolled in this study was limited, 1‐year follow‐up results showed a trend that patients with isolated central posterior leaflet prolapse and multisegment prolapse but dominated by central segment had more stable MR improvement, which was consistent with other reports. 15 , 16 Four patients had recurrence of moderate or more MR during 1‐year follow‐up.