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showed a trendp = 0.0210.4× alpha
Bipolar disorder polygenic risk score, childhood adversity and symptom dimensions BD-PRS showed a trend-level association with the positive dimension (β = −0.49, 95% CI = [−0.875, −0.102], p = 0.021) but no association with the negative (β = 0.09, 95% CI = [−0.288, 0.474], p = 0.654), manic (β = −0.19, 95% CI = [−0.582, 0.208], p = 0.387) or depressive dimensions (β = −0.20, 95% CI = [−0.585, 0.178], p = 0.330).
showed a trendp = 0.0210.4× alpha
Parent-child interaction frequency showed a trend towards significance in univariate analysis ( p = 0.021) but did not reach significance in multivariate analysis ( p = 0.117), suggesting it may still play a role in mitigating developmental risks. 3.8 ROC curve analysis of parents' electronic ST habits, young children's screen exposure and parent-child interaction on language development delay in young children The ROC curve analysis indicated that father's and mother's daily ST, along with total entertainment time, showed moderate discriminatory ability for predicting language development delays in young children ( Table 7 ).
showed a trendp = 0.0220.4× alpha
Discussion Our analysis of 6155 patients (mean follow-up: 5.47 years) found that raloxifene showed a trend toward lower TKR risk vs. bisphosphonates in crude analysis (HR 0.62, 95% CI 0.42–0.93, p = 0.022), but this association became non-significant in the traditional adjusted Cox model (aHR 0.71, 95% CI 0.47–1.07, p = 0.102).
showed a trendp = .0230.5× alpha
Specifically, they gave less negative evaluations of the negative scenes (this was significant for the category Distress t (11.36) = 3.64, p < .001, with trends in the same direction for scratch ( p = .034) and yawn ( p = .014)) and less positive ratings following positive scenes (which was significant for grooming t (11.36) = 3.44, p = .001 and showed a trend in play ( p = .023).
showed a trendP=0.0230.5× alpha
During a mean follow-up period of 34.6 months, the high-threshold group showed a trend toward a higher incidence of HB capture threshold of ≥2.5 V (50% vs. 14%; P=0.023), HBP abandonment (29% vs. 8.6%; P=0.091), lead revision (21% vs. 2.9%; P=0.065), and clinical events (all-cause death, heart failure hospitalization, and new-onset or progression of atrial fibrillation; 50% vs. 23%; P=0.089) than the low-threshold group.
showed a trendp = 0.0240.5× alpha
The ABR P1 latency showed a trend toward prolongation, with a significant difference observed at certain frequencies (two-way ANOVA, interaction: F (5, 95) = 2.72, p = 0.024; Šidák post hoc test: p = 0.0028, Cohen d = 2.58 at 8.00 kHz, p = 0.0089, Cohen d = 1.58 at 11.33 kHz, p = 0.019, Cohen d = 1.18 at 16.00 kHz, p < 0.0001, Cohen d = 2.74 at 22.65 kHz, p < 0.0001, Cohen d = 2.46 at 32.00 kHz; Fig 2D ).
showed a trendp = 2.56 × 10 −20.5× alpha
Meta-analysis integrating the results from the first and second cohorts demonstrated that mLOX was significantly increased in female suicide decedents compared to female controls (p = 2.66 × 10 −21 , OR = 4.00, 95%CI = 3.00–5.33), while mLOY showed a trend of rather protective associations with male suicide decedents (p = 2.56 × 10 −2 , OR = 0.71, 95%CI = 0.52–0.96) (Fig. 2 and Supplementary Table S3 ).