0.17% among females; P < 0.001) and the frequency by age groups showed a trend to increase until 40 years of age (Fig. 1 ), being much higher in people below that age (0.58%) compared to people aged > 40 years (0.05%; p < 0.001).
( 13 ) who state that the preoperative outcomes in the second period of surgeries [2016–2018]showed a trend towards better performance than in the first period [2013–2015], with shorter hospital (6.34±2.84 vs. 9.50±6.37 days, P<0.001), and ICU stays (1.15±0.59 vs. 1.94±2.08 days), and decreasing complication rates (19.40% vs. 45.80%, P=0.001), with an advantage in oncological results: 3-year OS of 73.5% [95% confidence interval (CI): 65.0–83.1%] vs. 57.4% (95% CI: 44.8–73.5%; P=0.047).
The UDVA value showed a trend of improvement in the control group ( p < 0.001), and the changes to SE and residual myopia were significantly lower in the control group (both p < 0.001).
The H2 blocker group also showed a trend toward poorer PFS (HR = 1.987, P < 0.001) and OS compared with those without antacid use (HR = 3.380, P = 0.226).
Patients with moderate and severe TR showed a trend towards a lower BMI (TR 0 29.8±5.5 kg/m 2 vs TR 1 27.9±4.9 kg/m 2 , TR 2 26.7±5.1 kg/m 2 and TR 3 26.9±5.0; p<0.001).
11 ) in the presence of FABP1 because the apparent K m for 4’-OH-diclofenac formation by CYP2C9 in the presence of hFABP1 (5.8 ± 1.5 μ M) only showed a trend for an increase ( P = 0.0011, 0.0729, 0.0416 for paired replicate experiments) when compared with in the absence of hFABP1 (1.4 ± 0.2 μ M) ( Supplemental Fig. 11 ; Table 2 ).
In contrast, the RABV-exposed group showed a trend towards lower frequencies of RABV-specific IFN-γ-secreting T cells at different timepoints with a significant decrease at M6 ( p = 0.0012) compared to the RABV-unexposed group (Fig. 5B ).
Both concentrations of FermCAE also showed a trend towards better antioxidant activity compared to respective concentrations of AQE, with a significant difference between the 2.5% extract groups ( p = 0.0014).
We performed Gene Set Enrichment Analysis (GSEA) on the differentially expressed genes and found that, compared with the NC group, the OGD + VK1 group showed a trend toward suppression of the cellular response to reactive oxygen species pathway ( p = 0.0017; p.adjust = 0.1457).
Enzymatic activity assays for SPHK1/2 showed a trend toward reduced activity ( Figure 1 D, p = 0.0018), indicating a decrease in both expression and activity of SPHK in human FRDA fibroblast cell lines.
The IVW analysis showed a trend-causing relationship between the brain cortex surficial area and succinylcarnitine levels ( β = 2.62 × 10 −05 , CI: 9.62 × 10 −06 to 4.24 × 10 −05 , p = 0.0019).
In addition, the number of days before maximum daily pollen occurrence showed a trend towards earlier pollen release during later years (R 2 = 0.287, p = 0.0019). 3.2.3.
The first class constantly maintained a higher and stable CF level, named the “Stable group”, with a proportion of 72.5%; The second class showed a trend of decline (Slope= -0.09, P = 0.002), was named the “Slow decline group”, with a proportion of 25.8%.
Fluid therapy with Plasmalyte-148 showed a trend toward faster DKA resolution at 24 hours (69% vs. 36%; OR 4.24, 95% CI 1.68-10.72; p = 0.002) compared to sodium chloride, though the difference at 48 hours was not statistically significant [ 15 ].
LT also showed a trend of reducing the risk of MS in multinomial logistic regression (Model 1, OR = 0.203, 95% CI: 0.072 to 0.569, P = 0.002; Model 2, OR = 0.149, 95% CI: 0.056 to 0.399, P < 0.001).
In contrast, the BP slope in the IH patients showed a trend towards a decrease with each hour (−0.3 mmHg/hr) during the first 24 hours, and this change was different from not only the same time period in controls (p=0.002, Figure 1 ), but also when compared to hours 25–44 in the IH patients (p=0.001).
Those who received chemotherapy also showed a trend for receiving tamoxifen (43.1% vs. 34.6%, P = 0.002).
Subgroup analysis by age showed a trend toward greater effect in <50-year-old participants ( p = 0.002) ( Supplementary Table S2 ).
In addition, larger tumor diameters (≥20 mm) showed a trend toward higher sensitivity (100% vs. 50%, p = 0.002) and concordance rate (100% vs. 80%, p = 0.002).
Nevertheless, the prevalence of dyslipidemia showed a trend of decreasing in boys (from 33.3 to 26.6%; P=0.002) and maintained in girls (from 28.4 to 30.2%; P=0.465), mainly due to a substantial decrease in hypo-HDL-cholesterolemia (9% reduction in boys, 5% reduction in girls).
The distribution of the dosing error among the referring health facilities (all the 13 [100%] patients from private hospitals, 66.7% from PHF, 60% from SHF, and 45.5% from THF) showed a trend of better performance ( p = 0.002) by the THFs.
The Wilcoxon signed rank test was not significant ( p =0.086), but showed a trend pointing into the same direction as the parametric mixed-effects model, which compares mean values ( p =0.002).
NLR also showed a trend ( p = 0.002), while BMI and lymphocyte count were not significantly associated (Fig.
Expression of miR-193a-3p was negatively correlated with that of CCND1 The result of the Pearson correlation analysis (two-tailed) showed a trend of negative correlation between miR-193a-3p and CCND1 in the RNA-sequencing database ( P = 0.002, R = −0.154) ( Fig. 6C ).
The incidence of scarring across the grades—grades I–IV (with distinctions based on lesion size)—showed a trend towards increased scarring with higher lesion grades, with rates ranging from 3.3% in grade I to 50.0% in grade IV lesions larger than 10 cm2 (p=0.002).