58<sup>th</sup> EASD Annual Meeting of the European Association for the Study of Diabetes : Stockholm, Sweden, 19 - 23 September 2022.

Diabetologia · 2022 · PMC9362525 · PMID 35920845

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.1400

boldest claim

The sentences

an increasing trendp<0.01actually significant

Results: MiR-148a-3p expression was significantly upregulated in islets from GK rats and an increasing trend was observed with increasing GK age (GK (11.5 weeks) vs GK (6 weeks): p<0.01, n≥3, and GK (13 weeks) vs W(Wistar) or GK (6 weeks): p<0.0001, n≥5).

also in 63,971 other papers

a significant trendp=0.022actually significant

Compared to no-DKD, RI was higher in all DKD PHs, being the highest in MA-DKD and with a significant trend of RI >0.70 prevalence to increase across PHs (p=0.022). aTRV3D and aPRV3D significantly differed across PHs (p<0.0001 for both).

also in 9,775 other papers

nearly reached significancep=0.087so close (0.05 < p ≤ 0.1)

Shc1 , encoding protein p66, was downregulated by 34% (p=0.05, n=4) after 48h, while a 26% reduction in Ncf1 gene, encoding p47phox, nearly reached significance after 96h (p=0.087, n=3).

also in 125 other papers

failed to reach significancep=0.09so close (0.05 < p ≤ 0.1)

Changes in HbA1c between the intervention groups was attenuated and failed to reach significance (p=0.09) after adjustment for age, sex and BMI changes.

also in 4,113 other papers

showed a trendp=0.09so close (0.05 < p ≤ 0.1)

Patients were also stratified using TIR, with largely similar findings.Participants with eGDR <8mg/kg -1 .min -1 showed a trend towards higher mean basal PS expression, but not P-selectin, compared with higher eGDR (PS 1216±1152 vs 458±163, p=0.09 ) .

also in 53,322 other papers

did not reach statistical significanceP=0.14not close (p > 0.1)

Pre-vaccination HbA1c was inversely related to peak-IgG, although the relationship did not reach statistical significance (r= -0.33; P=0.14).

also in 111,027 other papers

a positive trendno p-value reported

With the increase in MVPA time, the multifactor control rate showed a positive trend.

also in 11,005 other papers

borderline non-significantno p-value reported

Empagliflozin improved cardiac remodelling parameters via reduction of LVEDD at all time points in EFFORT-1, reaching significance only at week 24 with difference -7.88 (95% CI; -12.2, -3.61) from placebo, whereas borderline non-significant differences were shown at week 48 [-4.40 (95% CI; -8.84, 0.042)].

also in 434 other papers

failed to reach statistical significanceno p-value reported

Interestingly, in this analysis the difference in HbA1c reductions at with lower eGFR failed to reach statistical significance but a trend toward attenuated glucose lowering effects was noted.

also in 6,035 other papers

nominally significantno p-value reported

Across the 3 cohorts all 21 proteins with nominally significant P-values show positive association with DKD progression ( Figure 1 ).

also in 7,732 other papers

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